Q88SF0 (GALT_LACPL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Galactose-1-phosphate uridylyltransferase
Short name=Gal-1-P uridylyltransferase
EC=2.7.7.12

Alternative name(s):
UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	lp_3480

Organism

Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)

Taxonomic identifier

220668 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	487 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential HAMAP MF_00571.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 487	487	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_0000169910

Sequences

	Sequence		Length	Mass (Da)
	Q88SF0 [UniParc]. Last modified June 6, 2003. Version 1. Checksum: 70748FD7C6277E8B	FASTA	487	54,243
	10 20 30 40 50 60 MTSLDQFVTA VIASPSQYTE LDRIYVHNRV LGLVGEGDPI AASDDQLTSL TDALVKTAIQ 70 80 90 100 110 120 NGKIEATQSD EDILADQLMD LVTPLPSVLN QRFWDKYQVS PQTATDYFFN LSKANDYIKT 130 140 150 160 170 180 RAIAKNVVFP AKTPFGDLEI TINLSKPEKD PKAIAAARNQ PQDGYPLCQL CMQNEGYLGR 190 200 210 220 230 240 LGYPARSNHR IIRLTLGGNT WGFQYSPYAY FNEHSIFLDQ EHRPMVINRQ TFTNLLEIVQ 250 260 270 280 290 300 QFPHYFVGSN ADLPIVGGSM LSHEHYQGGR HEFPMMKAPI ARTIDLGIAG VKAGIVKWPM 310 320 330 340 350 360 STIRLTSQDL VALTDAAVKI HETWKNYSDE SVDVRAYTDG TRHHTTTPIA RKVGDDYVLD 370 380 390 400 410 420 IVLRDNQTSA EFPDGIFHPH QDVQHIKKEN IGLIEVMGRA ILPARLKTEL AEVGKYLLDQ 430 440 450 460 470 480 PNQMVAMHQA WAAQLKATNT ITADNVTTVI DTAVGNVFAR VLADAGVFKW DDAGEAAFDR FVAAMHD

References

[1]

"Complete genome sequence of Lactobacillus plantarum WCFS1." Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P., Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J., Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M., Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M., Siezen R.J. Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003) [PubMed: 12566566] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-793 / NCIMB 8826 / WCFS1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL935263 Genomic DNA. Translation: CCC80448.1.
RefSeq	NP_786688.1. NC_004567.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1063432.
GenomeReviews	Gene locus lp_3480 in contig AL935263_GR.
KEGG	lpl:lp_3480.
NMPDR	fig|220668.1.peg.2822.
PATRIC	22252596. VBILacPla27411_2896.
Phylogenomic databases
HOGENOM	HBG337915.
OMA	TWGFQYS.
ProtClustDB	PRK05270.
Enzyme and pathway databases
BioCyc	LPLA220668:LP_3480-MONOMER.
Family and domain databases
HAMAP	MF_00571. GalP_UDP_trans. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR023425. GalP_uridyl_Trfase_II_CS. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
KO	K00965.
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. GalT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_LACPL

Accession

Primary (citable) accession number: Q88SF0
Secondary accession number(s): F9UUE6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 6, 2003
Last sequence update:	June 6, 2003
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program