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Q88SD8 (AROD_LACPL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate dehydratase

Short name=3-dehydroquinase
EC=4.2.1.10
Alternative name(s):
Type I DHQase
Gene names
Name:aroD
Ordered Locus Names:lp_3493
OrganismLactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Taxonomic identifier220668 [NCBI]
Taxonomic lineageBacteriaFirmicutesLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length252 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP MF_00214

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP MF_00214

Subunit structure

Homodimer By similarity. HAMAP MF_00214

Sequence similarities

Belongs to the type-I 3-dehydroquinase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2522523-dehydroquinate dehydratase HAMAP MF_00214
PRO_0000138798

Sites

Active site1441Proton acceptor By similarity
Active site1711Schiff-base intermediate with substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q88SD8 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 584337A6FD3058FE

FASTA25227,216
        10         20         30         40         50         60 
MQPAIKLRNI ELGSCRPKLA VPITGTTIND ILAATTPILA AQPDVVEWRI DFFKDVTNPE 

        70         80         90        100        110        120 
QLKSAGQQLR QALGDIALLT TFRTKGEGGE LALSDTEYFK LCETVLDGGF TDALDVERYH 

       130        140        150        160        170        180 
DEQAVKQIVA AAHEHQVVVI MSNHDFDKTP AVAEIVKRLT SMVDYGADVA KMAVMPQSVE 

       190        200        210        220        230        240 
DVLTLLTATN IARQTLPQPV ITMSMGDLGK VSRLAGEVFG SCLSFATVGA ASAPGQIALE 

       250 
NLRPELEDLK LN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL935263 Genomic DNA. Translation: CCC80461.1.
RefSeqNP_786701.1. NC_004567.1.

3D structure databases

ProteinModelPortalQ88SD8.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1062990.
GenomeReviewsGene locus lp_3493 in contig AL935263_GR.
KEGGlpl:lp_3493.
NMPDRfig|220668.1.peg.2835.
PATRIC22252622. VBILacPla27411_2909.

Phylogenomic databases

HOGENOMHBG732926.
OMAIAKIAVM.
ProtClustDBPRK02412.

Enzyme and pathway databases

BioCycLPLA220668:LP_3493-MONOMER.

Family and domain databases

HAMAPMF_00214. AroD.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR001381. DHquinase_I.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK03785.
PfamPF01487. DHquinase_I. 1 hit.
[Graphical view]
TIGRFAMsTIGR01093. AroD. 1 hit.
PROSITEPS01028. DEHYDROQUINASE_I. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROD_LACPL
AccessionPrimary (citable) accession number: Q88SD8
Secondary accession number(s): F9UUF9
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: June 1, 2003
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families