Reviewed, UniProtKB/Swiss-Prot Q88S49 (RHAB_LACPL)

Names and origin

Protein names

Recommended name:
    Rhamnulokinase
    EC=2.7.1.5
Alternative name(s):
    Rhamnulose kinase

Gene names

Name:	rhaB
Ordered Locus Names:	lp_3595

Organism

Lactobacillus plantarum [Complete proteome] [HAMAP]

Taxonomic identifier

1590 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	488 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate. HAMAP MF_01535
Pathway	Carbohydrate degradation; L-rhamnose degradation; glycerone phosphate from L-rhamnose: step 2/3. HAMAP MF_01535
Sequence similarities	Belongs to the rhamnulokinase family.

Ontologies

Keywords
Biological process	Rhamnose metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rhamnose catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW rhamnulokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 488	488	Rhamnulokinase HAMAP MF_01535		PRO_0000090536
Regions
	Region	234 – 236	3	Substrate binding By similarity
Sites
	Binding site	12	1	ATP By similarity
	Binding site	257	1	ATP By similarity
	Binding site	294	1	Substrate By similarity
	Binding site	302	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q88S49-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 1155DC33710FD9FA	FASTA	488	55,266
	10 20 30 40 50 60 MKSYIAVDIG ASSGRLMLGQ QKRGQLTLKE VHRFSNGFAM KDGHDRWDVD HLIHEIFKGL 70 80 90 100 110 120 EKVKKMGIKD VELGIDTWAV DYVLVGENGH KLEDPISYRD KRTHNAIQQL TSDLPKEYIY 130 140 150 160 170 180 EKTGIQFQDF NTLYQLYKEN HDLLAKTDKI MMMPDYLGYV LTGNAVTEIT NASTTQMLNL 190 200 210 220 230 240 RVGLFDKDLL GKVNVSQDQF PRLVESGSVL GNVSHKWHTQ YDIPEVEVVT VATHDTASAV 250 260 270 280 290 300 VGTPGEGDRW AFLSSGTWSL LGTELNVPEN GLQAFHENYT NEWGAYGTYR FLKNIMGLWV 310 320 330 340 350 360 AQCVRHELGD QYSFGELADL AQQVRPFQQF IDINDERFTN PENMIKELQD YCRETKQTIP 370 380 390 400 410 420 ETPGELFQAI YSNLSLFYAN ELNKLDRILG YHIDTLNIVG GGSNVALMNQ LTSTLANIKV 430 440 450 460 470 480 VAGPSEATAV GNIMVQMITS DEVENIGAGR RLIETSFDLK RYLPETNKYG DILKEYQRFL TNKSKEMV

References

[1]

"Complete genome sequence of Lactobacillus plantarum WCFS1." Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P., Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J., Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M., Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M., Siezen R.J. Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003) [PubMed: 12566566] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-793 / NCIMB 8826 / WCFS1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL935262 Genomic DNA. Translation: CAD65672.1.
RefSeq	NP_786794.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1062088.
GenomeReviews	Gene locus lp_3595 in contig AL935263_GR.
KEGG	lpl:lp_3595.
NMPDR	fig|220668.1.peg.2928.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q88S49.
OMA	Q88S49. EIHRFKN.
Enzyme and pathway databases
BioCyc	LPLA220668:LP_3595-MON.
BRENDA	2.7.1.5. 593.
Family and domain databases
HAMAP	MF_01535. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018484. Carb_kinase_FGGY_N. IPR013449. Rhamnulokinase. [Graphical view]
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR02627. rhamnulo_kin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RHAB_LACPL

Accession

Primary (citable) accession number: Q88S49

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 12, 2005
Last sequence update:	June 1, 2003
Last modified:	June 16, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)