Reviewed, UniProtKB/Swiss-Prot Q88RQ6 (HEM6_PSEPK)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen 3 oxidase, aerobic
    EC=1.3.3.3
Alternative name(s):
    Coproporphyrinogen III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase

Gene names

Name:	hemF
Ordered Locus Names:	PP_0073

Organism

Pseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]

Taxonomic identifier

160488 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Coproporphyrinogen 3 oxidase, aerobic		PRO_0000109911

Sequences

	Sequence		Length	Mass (Da)
	Q88RQ6-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 1B3BCDE865A949F2	FASTA	303	34,393
	10 20 30 40 50 60 MTSRTEAVKA YLLDLQDRIC SALETEDGGA RFVEDAWVRE AGGGGRTRVI GEGNVIEKGG 70 80 90 100 110 120 VNFSHVFGSG LPPSASAHRP ELAGRGFEAL GVSLVIHPHN PHVPTSHANV RFFIAEKEGE 130 140 150 160 170 180 EAVWWFGGGF DLTPYYGNEE DCIHWHRVAE QACAPFGADV YPRYKAWCDR YFHLKHRGEP 190 200 210 220 230 240 RGIGGLFFDD LNEWDFDTCF AFIRAIGDAF VDAYLPIVQR RKNTPYTPQQ REFQEYRRGR 250 260 270 280 290 300 YVEFNLVYDR GTLFGLQSGG RTESILMSLP PQVRWGYDWK AAPGSEEARL TEYFLQDRDW LGQ

References

[1]

"Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440." Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H., Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M., Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F., Madupu R., Nelson W.C., White O. , Peterson J.D., Khouri H.M., Hance I., Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A., Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M. Environ. Microbiol. 4:799-808(2002) [PubMed: 12534463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE015451 Genomic DNA. Translation: AAN65707.1.
RefSeq	NP_742243.1.
3D structure databases
SMR	Q88RQ6. Positions 1-301.
ModBase	Search...
Genome annotation databases
GeneID	1043554.
GenomeReviews	Gene locus PP_0073 in contig AE015451_GR.
KEGG	ppu:PP_0073.
NMPDR	fig|160488.1.peg.73.
TIGR	PP_0073.
Phylogenomic databases
HOGENOM	Q88RQ6.
Enzyme and pathway databases
BioCyc	PPUT160488:PP_0073-MON.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
LinkHub	Q88RQ6.

Entry information

Entry name

HEM6_PSEPK

Accession

Primary (citable) accession number: Q88RQ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 14, 2003
Last sequence update:	June 1, 2003
Last modified:	November 4, 2008
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)