Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q88QX8 (MASZ_PSEPK)

Last modified November 3, 2009. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Malate synthase G
    EC=2.3.3.9
Gene names
Name: glcB
Ordered Locus Names: PP_0356
OrganismPseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]
Taxonomic identifier160488 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length725 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP MF_00641

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP MF_00641

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the malate synthase family. GlcB subfamily.

Ontologies

Keywords
   Biological processGlyoxylate bypass
Tricarboxylic acid cycle
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglyoxylate cycle

Inferred from electronic annotation. Source: HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmalate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 725725Malate synthase G HAMAP MF_00641
PRO_0000166893

Sites

Active site3401Proton acceptor By similarity
Active site6311Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q88QX8-1 [UniParc].

Last modified April 30, 2003. Version 1.
Checksum: 8363F218E6116AE1

FASTA72578,347
        10         20         30         40         50         60 
MTGYVQVGGL QVAKVLYDFV NNEAIPGTGI VAEQFWAGAE KIINDLAPKN KALLAKRDEL 

        70         80         90        100        110        120 
QAKIDAWHQA RKGQAHDAAA YKAFLQEIGY LLPQADDFQA TTQNVDEEIA HMAGPQLVVP 

       130        140        150        160        170        180 
VMNARFALNA ANARWGSLYD ALYGTDAISD EGGAEKGQGY NKVRGDKVIA FARAFLDEAA 

       190        200        210        220        230        240 
PLAAGSHVDS TGYRIEGGKL VVALKGGSNT GLRDDAQLIG FHGDAAAPTA VLLKHNGLHF 

       250        260        270        280        290        300 
EIQVDASTPV GSTDAAGVKD ILMESALTTI MDCEDSVAAV DADDKVIVYR NWLGLMKGDL 

       310        320        330        340        350        360 
AESVSKGGKT FTRTMNPDRE YAAPNGGSVT LHGRSLLFVR NVGHLMTNPA ILDAQGNEIP 

       370        380        390        400        410        420 
EGIQDGLFTN LIALHNLNGN TSRKNTRSGS VYIVKPKMHG PEEVAFATEI FSQVEDLLGM 

       430        440        450        460        470        480 
PRNTVKVGIM DEERRTTVNL KSCIKAAAER VVFINTGFLD RTGDEIHTSM EAGAVVRKGA 

       490        500        510        520        530        540 
MKNEKWIGAY ENNNVDVGLA TGLQGRAQIG KGMWAMPDLM AAMLEQKIAH PLAGANTAWV 

       550        560        570        580        590        600 
PSPTAATLHA LHYHKVDVQA RQRELASRTP ASVDDILAIP LAADTNWSAE EIRNELDNNA 

       610        620        630        640        650        660 
QGILGYVVRW IDQGVGCSKV PDINNVGLME DRATLRISAQ LLANWLRHGV VSQEQVLESL 

       670        680        690        700        710        720 
KRMAVVVDQQ NAGDPLYRPM APNFDDNVAF QAAVELVVEG GKQPNGYTEP VLHRRRREFK 


ARNGL 

« Hide

Cross-references

Sequence databases

AE015451 Genomic DNA. Translation: AAN65987.1.
RefSeqNP_742523.1.

3D structure databases

HSSPHSSP built from PDB template 1N8I based on UniProtKB Q50596.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ88QX8.

Genome annotation databases

GeneID1044063.
GenomeReviewsGene locus PP_0356 in contig AE015451_GR.
KEGGppu:PP_0356.
NMPDRfig|160488.1.peg.353.
TIGRPP_0356.

Phylogenomic databases

HOGENOMQ88QX8.
OMAPKMHGPD.

Enzyme and pathway databases

BioCycPPUT160488:PP_0356-MON.

Family and domain databases

HAMAPMF_00641.
[Tree]
InterProIPR011076. Malate_synth-like_core.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view]
PANTHERPTHR21631:SF1. Malate_synthase. 1 hit.
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01345. malate_syn_G. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMASZ_PSEPK
AccessionPrimary (citable) accession number: Q88QX8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: April 30, 2003
Last modified: November 3, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents