Reviewed,
UniProtKB/Swiss-Prot Q88QV6 (PQQC_PSEPK)
Last modified
November 4, 2008.
Version 37.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Pyrroloquinoline-quinone synthase EC=1.3.3.11 Alternative name(s): Coenzyme PQQ synthesis protein C Pyrroloquinoline quinone biosynthesis protein C | ||||
| Gene names |
| ||||
| Organism | Pseudomonas putida (strain KT2440) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 160488 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas |
Protein attributes
| Sequence length | 251 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. |
| Catalytic activity | 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H(2)O(2) + 2 H(2)O. |
| Pathway | Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. |
| Sequence similarities | Belongs to the pqqC family. |
Ontologies
Keywords | |
|---|---|
| Biological process | PQQ biosynthesis |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW pyrroloquinoline quinone biosynthetic processInferred from electronic annotation. Source: HAMAP |
| Molecular function | pyrroloquinoline-quinone synthase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 251 | 251 | Pyrroloquinoline-quinone synthase | PRO_0000219984 | |||
Sequences
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References
| [1] | "Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440." Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H., Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M., Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F., Madupu R., Nelson W.C., White O. Fraser C.M.Environ. Microbiol. 4:799-808(2002) [PubMed: 12534463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| AE015451 Genomic DNA. Translation: AAN66009.1. | |
| RefSeq | NP_742545.1. |
3D structure databases | |
| SMR | Q88QV6. Positions 7-246. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1044088. |
| GenomeReviews | Gene locus PP_0378 in contig AE015451_GR. |
| KEGG | ppu:PP_0378. |
| NMPDR | fig|160488.1.peg.375. |
| TIGR | PP_0378. |
Phylogenomic databases | |
| HOGENOM | Q88QV6. |
Enzyme and pathway databases | |
| BioCyc | PPUT160488:PP_0378-MON. |
Family and domain databases | |
| HAMAP | MF_00654. [Tree] |
| InterPro | IPR016084. Haem_Oase-like_multi-hlx. IPR011845. PQQ_synth_PqqC. IPR004305. TENA/THI4/PQQ_synth_PqqC. [Graphical view] |
| Gene3D | G3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit. |
| Pfam | PF03070. TENA_THI-4. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR02111. PQQ_syn_pqqC. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | PQQC_PSEPK | ||||||||
| Accession | Primary (citable) accession number: Q88QV6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


