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Q88QC7 (SPEA_PSEPK) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Biosynthetic arginine decarboxylase

Short name=ADC
EC=4.1.1.19
Gene names
Name:speA
Ordered Locus Names:PP_0567
OrganismPseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]
Taxonomic identifier160488 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length637 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the biosynthesis of agmatine from arginine By similarity. HAMAP-Rule MF_01417

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01417

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01417

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01417

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 637637Biosynthetic arginine decarboxylase HAMAP-Rule MF_01417
PRO_0000149972

Regions

Region290 – 30011Substrate-binding Potential

Amino acid modifications

Modified residue1101N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q88QC7 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: E59F5EA60F345738

FASTA63771,043
        10         20         30         40         50         60 
MSVRRTRKDD GSQWTVADSR SVYGIRHWGA GYFAINEAGR VEVRPNGPQS APIDLFEQVD 

        70         80         90        100        110        120 
ELRQSGLSLP LLVRFPDILQ DRVRQLTGAF DANIARLEYQ SQYTALYPIK VNQQEAVVEN 

       130        140        150        160        170        180 
IIATQNVSIG LEAGSKPELL AVLALAPKGG TIVCNGYKDR EFIRLALMGQ KLGHNVFIVI 

       190        200        210        220        230        240 
EKESEVALVI EEAAELKVKP QVGLRVRLSS LASSKWADTG GEKSKFGLSA AQLLSVVQRF 

       250        260        270        280        290        300 
RDAGLDQGIR LLHFHMGSQI ANLADYQHGF KEAIRYYGEL RALGLPVDHI DVGGGLGVDY 

       310        320        330        340        350        360 
DGTHSRNASS INYDMDDYAG VVVGMLKEFC DAQGLPHPHI FSESGRSLTA HHAMLVIQVT 

       370        380        390        400        410        420 
DVEKHNDDVP TIENKEALPE TVQWLVDLLG PTDIEMVTET YWRATHYMGD VAAQYADGKL 

       430        440        450        460        470        480 
SLGEKALAEQ CYFAVCRRLH NSLKARQRSH RQVLDELNDK LADKYICNFS VFQSLPDTWA 

       490        500        510        520        530        540 
IGQVLPIIPL HRLDEEPMRR AVLQDLTCDS DGKINQYVDE QSIETSMPVH AVKEGEDYLL 

       550        560        570        580        590        600 
GVFLVGAYQE ILGDMHNLFG DTDSVNIYQN ADGSVYHAGI ETHDTIEDML RYVHLSPEEL 

       610        620        630 
MTHYRDKVAS AKITARERTQ YLDALRLGLT RSSYLSS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015451 Genomic DNA. Translation: AAN66194.1.
RefSeqNP_742730.1. NC_002947.3.

3D structure databases

ProteinModelPortalQ88QC7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING160488.PP_0567.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN66194; AAN66194; PP_0567.
GeneID1044357.
KEGGppu:PP_0567.
PATRIC19939209. VBIPsePut30601_0605.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1166.
HOGENOMHOG000029191.
KOK01585.
OMAMIHFHIG.
OrthoDBEOG676Z0R.
ProtClustDBPRK05354.

Enzyme and pathway databases

BioCycPPUT160488:GIXO-585-MONOMER.

Family and domain databases

Gene3D2.40.37.10. 2 hits.
HAMAPMF_01417. SpeA.
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR000183. Orn/DAP/Arg_de-COase.
[Graphical view]
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR01273. speA. 1 hit.
PROSITEPS00879. ODR_DC_2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEA_PSEPK
AccessionPrimary (citable) accession number: Q88QC7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families