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Protein

Probable malate:quinone oxidoreductase 1

Gene

mqo1

Organism
Pseudomonas putida (strain KT2440)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase 3 (mqo3), Probable malate:quinone oxidoreductase 2 (mqo2), Probable malate:quinone oxidoreductase 1 (mqo1)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciPPUT160488:GIXO-782-MONOMER.
UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductase 1UniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQO 1UniRule annotation
Malate dehydrogenase [quinone] 1UniRule annotation
Gene namesi
Name:mqo1UniRule annotation
Synonyms:mqo-1
Ordered Locus Names:PP_0751
OrganismiPseudomonas putida (strain KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000556 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 502502Probable malate:quinone oxidoreductase 1PRO_0000128732Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi160488.PP_0751.

Structurei

3D structure databases

ProteinModelPortaliQ88PU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEAKAEDW.
OrthoDBiEOG6X6R8Z.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q88PU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQNESVDVV LVGAGIMSAT LAVLLKELDP TLKLEVVEAM DSGAAESSNP
60 70 80 90 100
WNNAGTGHAG LCELNYTPQA ADGSIDIKKA VHINTQFEVS RQFWAYLTKK
110 120 130 140 150
GNFGSARAFI NPVPHLSYVE GDKGVSFLKK RFELLKQHHA FAEMEYTEDK
160 170 180 190 200
AVMNDWMPLM MPGRPADQHI AATRVAKGTD VNFGALTNKL LKLLGDSPDA
210 220 230 240 250
QVKYSKKVVG LRRNGSGWTV SIKDVNSGGS REVDARFVFL GAGGAALPLL
260 270 280 290 300
QLSGIPESKG FGGFPVSGQW LRCDNPEIVK QHQAKVYSQA AVGAPPMSVP
310 320 330 340 350
HLDTRVVDGK TSLLFGPYAG FTTKFLKHGS LMDLPLSVRM GNIGPMLAVA
360 370 380 390 400
RDNMDLTKYL VSEVMQSMEQ RLEALRRFYP QAKAEDWRLE VAGQRVQIIK
410 420 430 440 450
KDPKKGGVLQ FGTELVSAQD GSLAALLGAS PGASVTVSIM LELIERCFPE
460 470 480 490 500
QAKGAWAAKL KEIFPAREKT LATDAALYHK ISADNDAALD LAESSPAAKH

YA
Length:502
Mass (Da):54,282
Last modified:June 1, 2003 - v1
Checksum:iBCEA30DACCA736E3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN66376.1.
RefSeqiNP_742912.1. NC_002947.4.
WP_010951993.1. NC_002947.4.

Genome annotation databases

EnsemblBacteriaiAAN66376; AAN66376; PP_0751.
GeneIDi1044587.
KEGGippu:PP_0751.
PATRICi19939635. VBIPsePut30601_0805.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN66376.1.
RefSeqiNP_742912.1. NC_002947.4.
WP_010951993.1. NC_002947.4.

3D structure databases

ProteinModelPortaliQ88PU7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160488.PP_0751.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN66376; AAN66376; PP_0751.
GeneIDi1044587.
KEGGippu:PP_0751.
PATRICi19939635. VBIPsePut30601_0805.

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEAKAEDW.
OrthoDBiEOG6X6R8Z.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.
BioCyciPPUT160488:GIXO-782-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KT2440.

Entry informationi

Entry nameiMQO1_PSEPK
AccessioniPrimary (citable) accession number: Q88PU7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: May 11, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.