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Q88PS4 (PTA_PSEPK) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:PP_0774
OrganismPseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]
Taxonomic identifier160488 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length695 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity.

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subunit structure

Homohexamer By similarity.

Subcellular location

Cytoplasm Potential.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similarities

In the N-terminal section; belongs to the CobB/CobQ family.

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 695695Phosphate acetyltransferase
PRO_0000405550

Regions

Region374 – 695322Phosphate acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
Q88PS4 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: CE730933D3FFC209

FASTA69574,643
        10         20         30         40         50         60 
MQTFFIAPTD FGVGLTSISL GLVRTLERAG LKVGFFKPIA QPHPGDTGPE RSTELVARTH 

        70         80         90        100        110        120 
GIKPPVPLSL AHVERMLGDG QLDELLEEII RLYQQACVGN DVVVVEGMVP TRHASYAARV 

       130        140        150        160        170        180 
NLHLAKSLDA EVILVSAPEN EVLSELSGRV ELQAQLFGGP RDPKVLGVIL NKVRTDESMA 

       190        200        210        220        230        240 
DFATRLREHS PLLRGNDFRL LGCIPYQPEL NAPRTRDVAE LLGAQVLNAG DYEQRRMSKI 

       250        260        270        280        290        300 
IICARTVANT VPLLTSGTLV VTPGDRDDII LAVSLAAING VPLAGLLLTS DSKPDVRILG 

       310        320        330        340        350        360 
LCRGALQAGL PILSVSTGSY DTANQLNSLN REIPVDDRER AEFITDFVAS HLDAAWLHQR 

       370        380        390        400        410        420 
CGTPRELRLS PAVFRYQLIQ RAQQANKRIV LPEGAEPLLV QAAAICQARG IARCVLLAKP 

       430        440        450        460        470        480 
EDVDAVARAQ GITLPPGLEI LDPELIRGRY VEPMVELRKS KNLNAPMAEQ QLEDPVVIGT 

       490        500        510        520        530        540 
MMLALDEVDG LVSGLVHSTA NTIRPALQLI KTAPGSSLVS SVFFMLFPEQ VLVYGDCVMN 

       550        560        570        580        590        600 
PHPSAAELAE IAQQSAASAQ AFGIAPRVAM ISYSSDSASD EEVEKVREAT RLAQDAAQEL 

       610        620        630        640        650        660 
LIDGPLQYDA AANPAIAREL APASPVAGRA TVFVFPDLNT GNTTHKAVQR SADGVSLGPM 

       670        680        690 
LQGLRKPVND LPRGAQVDDI VHTIALTAIQ ASVAR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015451 Genomic DNA. Translation: AAN66399.1.
RefSeqNP_742935.1. NC_002947.3.

3D structure databases

ProteinModelPortalQ88PS4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING160488.PP_0774.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN66399; AAN66399; PP_0774.
GeneID1044613.
KEGGppu:PP_0774.
PATRIC19939685. VBIPsePut30601_0830.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0280.
HOGENOMHOG000053797.
KOK13788.
OMAKPIAQPH.
OrthoDBEOG6BKJ5W.

Enzyme and pathway databases

BioCycPPUT160488:GIXO-805-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

Gene3D3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTA_PSEPK
AccessionPrimary (citable) accession number: Q88PS4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: June 1, 2003
Last modified: June 11, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways