Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphate acetyltransferase

Gene

pta

Organism
Pseudomonas putida (strain KT2440)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in acetate metabolism.By similarity

Catalytic activityi

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphate acetyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. acetyl-CoA biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciPPUT160488:GIXO-805-MONOMER.
UniPathwayiUPA00340; UER00459.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate acetyltransferase (EC:2.3.1.8)
Alternative name(s):
Phosphotransacetylase
Gene namesi
Name:pta
Ordered Locus Names:PP_0774
OrganismiPseudomonas putida (strain KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000556 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 695695Phosphate acetyltransferasePRO_0000405550Add
BLAST

Interactioni

Subunit structurei

Homohexamer.By similarity

Protein-protein interaction databases

STRINGi160488.PP_0774.

Structurei

3D structure databases

ProteinModelPortaliQ88PS4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni374 – 695322Phosphate acetyltransferaseAdd
BLAST

Domaini

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site (By similarity).By similarity

Sequence similaritiesi

In the N-terminal section; belongs to the CobB/CobQ family.Curated
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.Curated

Phylogenomic databases

eggNOGiCOG0280.
HOGENOMiHOG000053797.
KOiK13788.
OMAiKPIAQPH.
OrthoDBiEOG6BKJ5W.

Family and domain databases

Gene3Di3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamiPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFiPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsiTIGR00651. pta. 1 hit.

Sequencei

Sequence statusi: Complete.

Q88PS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTFFIAPTD FGVGLTSISL GLVRTLERAG LKVGFFKPIA QPHPGDTGPE
60 70 80 90 100
RSTELVARTH GIKPPVPLSL AHVERMLGDG QLDELLEEII RLYQQACVGN
110 120 130 140 150
DVVVVEGMVP TRHASYAARV NLHLAKSLDA EVILVSAPEN EVLSELSGRV
160 170 180 190 200
ELQAQLFGGP RDPKVLGVIL NKVRTDESMA DFATRLREHS PLLRGNDFRL
210 220 230 240 250
LGCIPYQPEL NAPRTRDVAE LLGAQVLNAG DYEQRRMSKI IICARTVANT
260 270 280 290 300
VPLLTSGTLV VTPGDRDDII LAVSLAAING VPLAGLLLTS DSKPDVRILG
310 320 330 340 350
LCRGALQAGL PILSVSTGSY DTANQLNSLN REIPVDDRER AEFITDFVAS
360 370 380 390 400
HLDAAWLHQR CGTPRELRLS PAVFRYQLIQ RAQQANKRIV LPEGAEPLLV
410 420 430 440 450
QAAAICQARG IARCVLLAKP EDVDAVARAQ GITLPPGLEI LDPELIRGRY
460 470 480 490 500
VEPMVELRKS KNLNAPMAEQ QLEDPVVIGT MMLALDEVDG LVSGLVHSTA
510 520 530 540 550
NTIRPALQLI KTAPGSSLVS SVFFMLFPEQ VLVYGDCVMN PHPSAAELAE
560 570 580 590 600
IAQQSAASAQ AFGIAPRVAM ISYSSDSASD EEVEKVREAT RLAQDAAQEL
610 620 630 640 650
LIDGPLQYDA AANPAIAREL APASPVAGRA TVFVFPDLNT GNTTHKAVQR
660 670 680 690
SADGVSLGPM LQGLRKPVND LPRGAQVDDI VHTIALTAIQ ASVAR
Length:695
Mass (Da):74,643
Last modified:June 1, 2003 - v1
Checksum:iCE730933D3FFC209
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN66399.1.
RefSeqiNP_742935.1. NC_002947.3.

Genome annotation databases

EnsemblBacteriaiAAN66399; AAN66399; PP_0774.
GeneIDi1044613.
KEGGippu:PP_0774.
PATRICi19939685. VBIPsePut30601_0830.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN66399.1.
RefSeqiNP_742935.1. NC_002947.3.

3D structure databases

ProteinModelPortaliQ88PS4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160488.PP_0774.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN66399; AAN66399; PP_0774.
GeneIDi1044613.
KEGGippu:PP_0774.
PATRICi19939685. VBIPsePut30601_0830.

Phylogenomic databases

eggNOGiCOG0280.
HOGENOMiHOG000053797.
KOiK13788.
OMAiKPIAQPH.
OrthoDBiEOG6BKJ5W.

Enzyme and pathway databases

UniPathwayiUPA00340; UER00459.
BioCyciPPUT160488:GIXO-805-MONOMER.

Family and domain databases

Gene3Di3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamiPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFiPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsiTIGR00651. pta. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KT2440.

Entry informationi

Entry nameiPTA_PSEPK
AccessioniPrimary (citable) accession number: Q88PS4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: June 1, 2003
Last modified: February 4, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.