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Protein

Phosphate acetyltransferase

Gene

pta

Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in acetate metabolism.By similarity

Catalytic activityi

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathwayi: acetyl-CoA biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes acetyl-CoA from acetate.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphate acetyltransferase (pta)
This subpathway is part of the pathway acetyl-CoA biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes acetyl-CoA from acetate, the pathway acetyl-CoA biosynthesis and in Metabolic intermediate biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciPPUT160488:G1G01-850-MONOMER
UniPathwayiUPA00340; UER00459

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate acetyltransferase (EC:2.3.1.8)
Alternative name(s):
Phosphotransacetylase
Gene namesi
Name:pta
Ordered Locus Names:PP_0774
OrganismiPseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000556 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004055501 – 695Phosphate acetyltransferaseAdd BLAST695

Proteomic databases

PRIDEiQ88PS4

Interactioni

Subunit structurei

Homohexamer.By similarity

Protein-protein interaction databases

STRINGi160488.PP_0774

Structurei

3D structure databases

ProteinModelPortaliQ88PS4
SMRiQ88PS4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni374 – 695Phosphate acetyltransferaseAdd BLAST322

Domaini

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site (By similarity).By similarity

Sequence similaritiesi

In the N-terminal section; belongs to the CobB/CobQ family.Curated
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.Curated

Phylogenomic databases

eggNOGiENOG4105C6K Bacteria
COG0280 LUCA
COG0857 LUCA
HOGENOMiHOG000053797
KOiK13788
OMAiTPLMFEY

Family and domain databases

Gene3Di3.40.1390.20, 1 hit
InterProiView protein in InterPro
IPR010766 DRTGG
IPR016475 P-Actrans_bac
IPR027417 P-loop_NTPase
IPR004614 P_AcTrfase
IPR002505 PTA_PTB
IPR028979 Ser_kin/Pase_Hpr-like_N_sf
PfamiView protein in Pfam
PF07085 DRTGG, 1 hit
PF01515 PTA_PTB, 1 hit
PIRSFiPIRSF006107 PhpActrans_proteobac, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF75138 SSF75138, 1 hit
TIGRFAMsiTIGR00651 pta, 1 hit

Sequencei

Sequence statusi: Complete.

Q88PS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTFFIAPTD FGVGLTSISL GLVRTLERAG LKVGFFKPIA QPHPGDTGPE
60 70 80 90 100
RSTELVARTH GIKPPVPLSL AHVERMLGDG QLDELLEEII RLYQQACVGN
110 120 130 140 150
DVVVVEGMVP TRHASYAARV NLHLAKSLDA EVILVSAPEN EVLSELSGRV
160 170 180 190 200
ELQAQLFGGP RDPKVLGVIL NKVRTDESMA DFATRLREHS PLLRGNDFRL
210 220 230 240 250
LGCIPYQPEL NAPRTRDVAE LLGAQVLNAG DYEQRRMSKI IICARTVANT
260 270 280 290 300
VPLLTSGTLV VTPGDRDDII LAVSLAAING VPLAGLLLTS DSKPDVRILG
310 320 330 340 350
LCRGALQAGL PILSVSTGSY DTANQLNSLN REIPVDDRER AEFITDFVAS
360 370 380 390 400
HLDAAWLHQR CGTPRELRLS PAVFRYQLIQ RAQQANKRIV LPEGAEPLLV
410 420 430 440 450
QAAAICQARG IARCVLLAKP EDVDAVARAQ GITLPPGLEI LDPELIRGRY
460 470 480 490 500
VEPMVELRKS KNLNAPMAEQ QLEDPVVIGT MMLALDEVDG LVSGLVHSTA
510 520 530 540 550
NTIRPALQLI KTAPGSSLVS SVFFMLFPEQ VLVYGDCVMN PHPSAAELAE
560 570 580 590 600
IAQQSAASAQ AFGIAPRVAM ISYSSDSASD EEVEKVREAT RLAQDAAQEL
610 620 630 640 650
LIDGPLQYDA AANPAIAREL APASPVAGRA TVFVFPDLNT GNTTHKAVQR
660 670 680 690
SADGVSLGPM LQGLRKPVND LPRGAQVDDI VHTIALTAIQ ASVAR
Length:695
Mass (Da):74,643
Last modified:June 1, 2003 - v1
Checksum:iCE730933D3FFC209
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA Translation: AAN66399.1
RefSeqiNP_742935.1, NC_002947.4
WP_010952014.1, NC_002947.4

Genome annotation databases

EnsemblBacteriaiAAN66399; AAN66399; PP_0774
GeneIDi1044613
KEGGippu:PP_0774
PATRICifig|160488.4.peg.830

Similar proteinsi

Entry informationi

Entry nameiPTA_PSEPK
AccessioniPrimary (citable) accession number: Q88PS4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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