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Q88PS4

- PTA_PSEPK

UniProt

Q88PS4 - PTA_PSEPK

Protein

Phosphate acetyltransferase

Gene

pta

Organism
Pseudomonas putida (strain KT2440)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Involved in acetate metabolism.By similarity

    Catalytic activityi

    Acetyl-CoA + phosphate = CoA + acetyl phosphate.

    Pathwayi

    GO - Molecular functioni

    1. phosphate acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. acetyl-CoA biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciPPUT160488:GIXO-805-MONOMER.
    UniPathwayiUPA00340; UER00459.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphate acetyltransferase (EC:2.3.1.8)
    Alternative name(s):
    Phosphotransacetylase
    Gene namesi
    Name:pta
    Ordered Locus Names:PP_0774
    OrganismiPseudomonas putida (strain KT2440)
    Taxonomic identifieri160488 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000000556: Chromosome

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 695695Phosphate acetyltransferasePRO_0000405550Add
    BLAST

    Interactioni

    Subunit structurei

    Homohexamer.By similarity

    Protein-protein interaction databases

    STRINGi160488.PP_0774.

    Structurei

    3D structure databases

    ProteinModelPortaliQ88PS4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni374 – 695322Phosphate acetyltransferaseAdd
    BLAST

    Domaini

    The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.By similarity

    Sequence similaritiesi

    In the N-terminal section; belongs to the CobB/CobQ family.Curated
    In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.Curated

    Phylogenomic databases

    eggNOGiCOG0280.
    HOGENOMiHOG000053797.
    KOiK13788.
    OMAiKPIAQPH.
    OrthoDBiEOG6BKJ5W.

    Family and domain databases

    Gene3Di3.40.1390.20. 1 hit.
    3.40.50.300. 1 hit.
    InterProiIPR010766. DRTGG.
    IPR016475. P-Actrans_bac.
    IPR027417. P-loop_NTPase.
    IPR004614. P_AcTrfase.
    IPR002505. PTA_PTB.
    IPR028979. Ser_kin/Pase_Hpr_N_like.
    [Graphical view]
    PfamiPF07085. DRTGG. 1 hit.
    PF01515. PTA_PTB. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006107. PhpActrans_proteobac. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    SSF75138. SSF75138. 1 hit.
    TIGRFAMsiTIGR00651. pta. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q88PS4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQTFFIAPTD FGVGLTSISL GLVRTLERAG LKVGFFKPIA QPHPGDTGPE    50
    RSTELVARTH GIKPPVPLSL AHVERMLGDG QLDELLEEII RLYQQACVGN 100
    DVVVVEGMVP TRHASYAARV NLHLAKSLDA EVILVSAPEN EVLSELSGRV 150
    ELQAQLFGGP RDPKVLGVIL NKVRTDESMA DFATRLREHS PLLRGNDFRL 200
    LGCIPYQPEL NAPRTRDVAE LLGAQVLNAG DYEQRRMSKI IICARTVANT 250
    VPLLTSGTLV VTPGDRDDII LAVSLAAING VPLAGLLLTS DSKPDVRILG 300
    LCRGALQAGL PILSVSTGSY DTANQLNSLN REIPVDDRER AEFITDFVAS 350
    HLDAAWLHQR CGTPRELRLS PAVFRYQLIQ RAQQANKRIV LPEGAEPLLV 400
    QAAAICQARG IARCVLLAKP EDVDAVARAQ GITLPPGLEI LDPELIRGRY 450
    VEPMVELRKS KNLNAPMAEQ QLEDPVVIGT MMLALDEVDG LVSGLVHSTA 500
    NTIRPALQLI KTAPGSSLVS SVFFMLFPEQ VLVYGDCVMN PHPSAAELAE 550
    IAQQSAASAQ AFGIAPRVAM ISYSSDSASD EEVEKVREAT RLAQDAAQEL 600
    LIDGPLQYDA AANPAIAREL APASPVAGRA TVFVFPDLNT GNTTHKAVQR 650
    SADGVSLGPM LQGLRKPVND LPRGAQVDDI VHTIALTAIQ ASVAR 695
    Length:695
    Mass (Da):74,643
    Last modified:June 1, 2003 - v1
    Checksum:iCE730933D3FFC209
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015451 Genomic DNA. Translation: AAN66399.1.
    RefSeqiNP_742935.1. NC_002947.3.

    Genome annotation databases

    EnsemblBacteriaiAAN66399; AAN66399; PP_0774.
    GeneIDi1044613.
    KEGGippu:PP_0774.
    PATRICi19939685. VBIPsePut30601_0830.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015451 Genomic DNA. Translation: AAN66399.1 .
    RefSeqi NP_742935.1. NC_002947.3.

    3D structure databases

    ProteinModelPortali Q88PS4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 160488.PP_0774.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN66399 ; AAN66399 ; PP_0774 .
    GeneIDi 1044613.
    KEGGi ppu:PP_0774.
    PATRICi 19939685. VBIPsePut30601_0830.

    Phylogenomic databases

    eggNOGi COG0280.
    HOGENOMi HOG000053797.
    KOi K13788.
    OMAi KPIAQPH.
    OrthoDBi EOG6BKJ5W.

    Enzyme and pathway databases

    UniPathwayi UPA00340 ; UER00459 .
    BioCyci PPUT160488:GIXO-805-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1390.20. 1 hit.
    3.40.50.300. 1 hit.
    InterProi IPR010766. DRTGG.
    IPR016475. P-Actrans_bac.
    IPR027417. P-loop_NTPase.
    IPR004614. P_AcTrfase.
    IPR002505. PTA_PTB.
    IPR028979. Ser_kin/Pase_Hpr_N_like.
    [Graphical view ]
    Pfami PF07085. DRTGG. 1 hit.
    PF01515. PTA_PTB. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006107. PhpActrans_proteobac. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    SSF75138. SSF75138. 1 hit.
    TIGRFAMsi TIGR00651. pta. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KT2440.

    Entry informationi

    Entry nameiPTA_PSEPK
    AccessioniPrimary (citable) accession number: Q88PS4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 8, 2011
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3