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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Pseudomonas putida (strain KT2440)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciPPUT160488:GIXO-1059-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:PP_1027
OrganismiPseudomonas putida (strain KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000556 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 459459Exodeoxyribonuclease 7 large subunitPRO_0000197867Add
BLAST

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi160488.PP_1027.

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229265.
KOiK03601.
OMAiFRQNATR.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q88P26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKDPFERLG LDREVLTVSQ LNGRARVLLE DVFRSVWVEG EISNLARPAS
60 70 80 90 100
GHMYFTLKDS GAQVRCALFR QNATRVRQAL RDGLAVRVRG KVSLFEGRGD
110 120 130 140 150
YQLILDTVEP AGDGALRLAF EALKEKLGAE GLFSAERKKP LPAHPQRIGI
160 170 180 190 200
ITSPTGAVIR DIISVFGRRA PQVELNLIPT AVQGREAIAQ IVRAIRLADS
210 220 230 240 250
LGFDALILAR GGGSLEDLWC FNEEAVARAV AACVTPIVSA VGHETDVSIS
260 270 280 290 300
DFVADVRAPT PSAAAELLAP DNSGLRQRLD GLQRRLLLRM QNRLTHDRLR
310 320 330 340 350
LESLTRRLRH PGERLRQRAQ RLDDLDMRLR RAFMLNLNQR RERLARLDAR
360 370 380 390 400
LAAQHPGRNL KLLNQRLDSL AERLPRAMRE VLKDRRQRFQ AQLQTLQVVS
410 420 430 440 450
PLATLARGYS ILLDEQGQAI RSAEQTRNGQ RLTARLNEGE LLVRVEDNHL

TPVTLSLLD
Length:459
Mass (Da):51,388
Last modified:June 6, 2003 - v1
Checksum:i5ADBA8C23F3C25EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN66652.1.
RefSeqiNP_743188.1. NC_002947.4.
WP_010952206.1. NC_002947.4.

Genome annotation databases

EnsemblBacteriaiAAN66652; AAN66652; PP_1027.
GeneIDi1044154.
KEGGippu:PP_1027.
PATRICi19940208. VBIPsePut30601_1090.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN66652.1.
RefSeqiNP_743188.1. NC_002947.4.
WP_010952206.1. NC_002947.4.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160488.PP_1027.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN66652; AAN66652; PP_1027.
GeneIDi1044154.
KEGGippu:PP_1027.
PATRICi19940208. VBIPsePut30601_1090.

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229265.
KOiK03601.
OMAiFRQNATR.

Enzyme and pathway databases

BioCyciPPUT160488:GIXO-1059-MONOMER.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEX7L_PSEPK
AccessioniPrimary (citable) accession number: Q88P26
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 6, 2003
Last sequence update: June 6, 2003
Last modified: September 7, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.