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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciPPUT160488:G1G01-1100-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:PP_1027
OrganismiPseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001978671 – 459Exodeoxyribonuclease 7 large subunitAdd BLAST459

Proteomic databases

PRIDEiQ88P26

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi160488.PP_1027

Structurei

3D structure databases

SMRiQ88P26
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVS Bacteria
COG1570 LUCA
HOGENOMiHOG000229265
KOiK03601
OMAiNARRRWP

Family and domain databases

CDDicd04489 ExoVII_LU_OBF, 1 hit
HAMAPiMF_00378 Exonuc_7_L, 1 hit
InterProiView protein in InterPro
IPR003753 Exonuc_VII_L
IPR020579 Exonuc_VII_lsu_C
IPR025824 OB-fold_nuc-bd_dom
PANTHERiPTHR30008 PTHR30008, 1 hit
PfamiView protein in Pfam
PF02601 Exonuc_VII_L, 1 hit
PF13742 tRNA_anti_2, 1 hit
TIGRFAMsiTIGR00237 xseA, 1 hit

Sequencei

Sequence statusi: Complete.

Q88P26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKDPFERLG LDREVLTVSQ LNGRARVLLE DVFRSVWVEG EISNLARPAS
60 70 80 90 100
GHMYFTLKDS GAQVRCALFR QNATRVRQAL RDGLAVRVRG KVSLFEGRGD
110 120 130 140 150
YQLILDTVEP AGDGALRLAF EALKEKLGAE GLFSAERKKP LPAHPQRIGI
160 170 180 190 200
ITSPTGAVIR DIISVFGRRA PQVELNLIPT AVQGREAIAQ IVRAIRLADS
210 220 230 240 250
LGFDALILAR GGGSLEDLWC FNEEAVARAV AACVTPIVSA VGHETDVSIS
260 270 280 290 300
DFVADVRAPT PSAAAELLAP DNSGLRQRLD GLQRRLLLRM QNRLTHDRLR
310 320 330 340 350
LESLTRRLRH PGERLRQRAQ RLDDLDMRLR RAFMLNLNQR RERLARLDAR
360 370 380 390 400
LAAQHPGRNL KLLNQRLDSL AERLPRAMRE VLKDRRQRFQ AQLQTLQVVS
410 420 430 440 450
PLATLARGYS ILLDEQGQAI RSAEQTRNGQ RLTARLNEGE LLVRVEDNHL

TPVTLSLLD
Length:459
Mass (Da):51,388
Last modified:June 6, 2003 - v1
Checksum:i5ADBA8C23F3C25EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA Translation: AAN66652.1
RefSeqiNP_743188.1, NC_002947.4
WP_010952206.1, NC_002947.4

Genome annotation databases

EnsemblBacteriaiAAN66652; AAN66652; PP_1027
GeneIDi1044154
KEGGippu:PP_1027
PATRICifig|160488.4.peg.1090

Similar proteinsi

Entry informationi

Entry nameiEX7L_PSEPK
AccessioniPrimary (citable) accession number: Q88P26
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2003
Last sequence update: June 6, 2003
Last modified: May 23, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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