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Protein

Probable malate:quinone oxidoreductase 2

Gene

mqo2

Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase 3 (mqo3), Probable malate:quinone oxidoreductase 2 (mqo2), Probable malate:quinone oxidoreductase 1 (mqo1)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductase 2UniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQO 2UniRule annotation
Malate dehydrogenase [quinone] 2UniRule annotation
Gene namesi
Name:mqo2UniRule annotation
Synonyms:mqo-2
Ordered Locus Names:PP_1251
OrganismiPseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000556 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001287331 – 527Probable malate:quinone oxidoreductase 2Add BLAST527

Interactioni

Protein-protein interaction databases

STRINGi160488.PP_1251.

Structurei

3D structure databases

ProteinModelPortaliQ88NF9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiPQHDMAL.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q88NF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQAHAAETKK VDVLLVGGGI MSSTLAVWLH ELEPSWSMEM VERLDGVAEE
60 70 80 90 100
SSNGWNNAGT GHSALAELNY TPEDKDGNVN ISKAIEINEA FQISRQFWSW
110 120 130 140 150
QVRQGVLKNP HSFINTTPHM SFVWGDDNIK FLKKRYDALQ ASPLFRPMQY
160 170 180 190 200
SEDHAQIAKW VPLMMEGRDP NQKLAVTWTP IGTDVNFGEI TRQFVGHLQT
210 220 230 240 250
QKGFELKLSS EVQDITRNKD GSWHVEYKNL KDGTESATDA KFLFIGAGGG
260 270 280 290 300
ALKLLQKSGI PEAKEYAGFP VGGSFLVTEN PTVAMQHMAK AYGIASTGAP
310 320 330 340 350
PMSVPHLDTR VLDGKRVILF GPFATFSTKF LKNGSYLDLL SSTTTHNVWP
360 370 380 390 400
MTKVGIDQYP LVEYLAGQLM LSDDDRFEAL RTYFPNAKKE EWRLWQAGQR
410 420 430 440 450
VQIIKRDAEK GGVLKLGTEV VASEDRTIAG LLGASPGAST AAPIMLHVLE
460 470 480 490 500
TVFKEKVATP EWQAKIKEIV PSYGTKLNDS AAATQKEWNY TAEVLQLGKP
510 520
PVIDASVEFG GAASKPVESK PENDMAL
Length:527
Mass (Da):58,117
Last modified:June 1, 2003 - v1
Checksum:iF7E5B8231255BF0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN66875.1.
RefSeqiNP_743411.3. NC_002947.4.
WP_061405581.1. NC_002947.4.

Genome annotation databases

GeneIDi1042466.
KEGGippu:PP_1251.
PATRICi19940697. VBIPsePut30601_1327.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN66875.1.
RefSeqiNP_743411.3. NC_002947.4.
WP_061405581.1. NC_002947.4.

3D structure databases

ProteinModelPortaliQ88NF9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160488.PP_1251.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1042466.
KEGGippu:PP_1251.
PATRICi19940697. VBIPsePut30601_1327.

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiPQHDMAL.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMQO2_PSEPK
AccessioniPrimary (citable) accession number: Q88NF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: November 2, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.