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Protein

Probable malate:quinone oxidoreductase 2

Gene

mqo2

Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase 3 (mqo3), Probable malate:quinone oxidoreductase 2 (mqo2), Probable malate:quinone oxidoreductase 1 (mqo1)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciPPUT160488:G1G01-1338-MONOMER
UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductase 2UniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQO 2UniRule annotation
Malate dehydrogenase [quinone] 2UniRule annotation
Gene namesi
Name:mqo2UniRule annotation
Synonyms:mqo-2
Ordered Locus Names:PP_1251
OrganismiPseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000556 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001287331 – 527Probable malate:quinone oxidoreductase 2Add BLAST527

Proteomic databases

PRIDEiQ88NF9

Interactioni

Protein-protein interaction databases

STRINGi160488.PP_1251

Structurei

3D structure databases

ProteinModelPortaliQ88NF9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiEPIAATK

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 2 hits
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

Q88NF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQAHAAETKK VDVLLVGGGI MSSTLAVWLH ELEPSWSMEM VERLDGVAEE
60 70 80 90 100
SSNGWNNAGT GHSALAELNY TPEDKDGNVN ISKAIEINEA FQISRQFWSW
110 120 130 140 150
QVRQGVLKNP HSFINTTPHM SFVWGDDNIK FLKKRYDALQ ASPLFRPMQY
160 170 180 190 200
SEDHAQIAKW VPLMMEGRDP NQKLAVTWTP IGTDVNFGEI TRQFVGHLQT
210 220 230 240 250
QKGFELKLSS EVQDITRNKD GSWHVEYKNL KDGTESATDA KFLFIGAGGG
260 270 280 290 300
ALKLLQKSGI PEAKEYAGFP VGGSFLVTEN PTVAMQHMAK AYGIASTGAP
310 320 330 340 350
PMSVPHLDTR VLDGKRVILF GPFATFSTKF LKNGSYLDLL SSTTTHNVWP
360 370 380 390 400
MTKVGIDQYP LVEYLAGQLM LSDDDRFEAL RTYFPNAKKE EWRLWQAGQR
410 420 430 440 450
VQIIKRDAEK GGVLKLGTEV VASEDRTIAG LLGASPGAST AAPIMLHVLE
460 470 480 490 500
TVFKEKVATP EWQAKIKEIV PSYGTKLNDS AAATQKEWNY TAEVLQLGKP
510 520
PVIDASVEFG GAASKPVESK PENDMAL
Length:527
Mass (Da):58,117
Last modified:June 1, 2003 - v1
Checksum:iF7E5B8231255BF0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA Translation: AAN66875.1
RefSeqiNP_743411.3, NC_002947.4
WP_061405581.1, NC_002947.4

Genome annotation databases

EnsemblBacteriaiAAN66875; AAN66875; PP_1251
GeneIDi1042466
KEGGippu:PP_1251
PATRICifig|160488.4.peg.1327

Similar proteinsi

Entry informationi

Entry nameiMQO2_PSEPK
AccessioniPrimary (citable) accession number: Q88NF9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
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