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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Pseudomonas putida (strain KT2440)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei137 – 1371UniRule annotation
Active sitei542 – 5421UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciPPUT160488:GIXO-1546-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:PP_1505
OrganismiPseudomonas putida (strain KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000556 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 875875Phosphoenolpyruvate carboxylasePRO_0000166614Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi160488.PP_1505.

Structurei

3D structure databases

ProteinModelPortaliQ88MR4.
SMRiQ88MR4. Positions 7-875.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q88MR4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDIDVRLRE DVHVLGELLG ETIRQQHGDA FLQKIEDIRH SAKADRRGPG
60 70 80 90 100
EQLSSTLADL AEEDLLPVAR AFNQFLNLAN MAEQYQLIRR RDADQPEPFE
110 120 130 140 150
AQVLPELLGR LKQAGHSNDA LARQLAKLDI QLVLTAHPTE VARRTLIQKY
160 170 180 190 200
DAIAGQLAAQ DHRDLTPAER QQVRERLRRL IAEAWHTEEI RRTRPTPVDE
210 220 230 240 250
AKWGFAVIEH SLWHAIPSHL RKVDKALLEA TGLRLPLEAA PIRFASWMGG
260 270 280 290 300
DRDGNPNVTA AVTREVLLLA RWMAADLFLR DIDALAAELS MQQANDTLRK
310 320 330 340 350
QVGDSAEPYR AVLKQLRDRL RATRAWAHSA LTSNQPAGAD VLVDNRELIA
360 370 380 390 400
PLELCYQSLH ECGMGVIAEG PLLDCLRRAV TFGLFLGRLD VRQDAARHRD
410 420 430 440 450
ALTEITDYLG LGRYADWDEE QRIAFLQAEL KNRRPLLPAH FKPQADTAEV
460 470 480 490 500
LATCREVAAA PAASLGSYVI SMAGAASDVL AVQLLLKEAG LTRPMRVVPL
510 520 530 540 550
FETLADLDNA GPVMQRLLGL PGYRAGLRGP QEVMIGYSDS AKDAGTTAAA
560 570 580 590 600
WAQYRAQENL VRICAEHQVE LLLFHGRGGT VGRGGGPAHA AILSQPPGSV
610 620 630 640 650
AGRFRTTEQG EMIRFKFGLP GIAEQNLNLY LAAVLEATLL PPPPPQPAWR
660 670 680 690 700
EVMDQLAADG VQAYRSVVRE NPDFVEYFRQ STPEQELGRL PLGSRPAKRR
710 720 730 740 750
AGGIESLRAI PWIFGWTQTR LMLPAWLGWE TALTNALARG QGELLAQMRE
760 770 780 790 800
QWPFFRTRID MLEMVLAKAD AQIAEAYDER LVQPHLRPLG AHLRDLLSQS
810 820 830 840 850
CQVVLGLTGQ PVLLAHSPET LEFISLRNTY LDPLHRLQAE LLARSRSREA
860 870
ALDSPLEQAL LVTVAGIAAG LRNTG
Length:875
Mass (Da):96,964
Last modified:June 1, 2003 - v1
Checksum:i173B89B82C761F07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN67126.1.
RefSeqiNP_743662.1. NC_002947.3.
WP_010952597.1. NC_002947.3.

Genome annotation databases

EnsemblBacteriaiAAN67126; AAN67126; PP_1505.
GeneIDi1045514.
KEGGippu:PP_1505.
PATRICi19941238. VBIPsePut30601_1596.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN67126.1.
RefSeqiNP_743662.1. NC_002947.3.
WP_010952597.1. NC_002947.3.

3D structure databases

ProteinModelPortaliQ88MR4.
SMRiQ88MR4. Positions 7-875.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160488.PP_1505.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN67126; AAN67126; PP_1505.
GeneIDi1045514.
KEGGippu:PP_1505.
PATRICi19941238. VBIPsePut30601_1596.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciPPUT160488:GIXO-1546-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KT2440.

Entry informationi

Entry nameiCAPP_PSEPK
AccessioniPrimary (citable) accession number: Q88MR4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: April 29, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.