Reviewed, UniProtKB/Swiss-Prot Q88LW9 (G6PI1_PSEPK)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase 1
      Short name=GPI 1
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase 1
      Short name=PGI 1
    Phosphohexose isomerase 1
      Short name=PHI 1

Gene names

Name:	pgi1
Synonyms:	pgi-1
Ordered Locus Names:	PP_1808

Organism

Pseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]

Taxonomic identifier

160488 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	554 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 554	554	Glucose-6-phosphate isomerase 1 HAMAP MF_00473		PRO_0000180711
Sites
	Active site	359	1	Proton donor By similarity
	Active site	390	1	By similarity
	Active site	518	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q88LW9-1 [UniParc]. Last modified May 23, 2003. Version 1. Checksum: 088DD58137B3C135	FASTA	554	61,384
	10 20 30 40 50 60 MAFYRTPHDV TALPAWKALQ QHREAMRGFS MSEAFAADAK RFDQFSLSAC GLFLDYSKNL 70 80 90 100 110 120 ITEQSRDLLV NLANEVGLQD AIKSMFSGEI INASEGRPVL HTALRRPVGD KLSVNGVNVM 130 140 150 160 170 180 PEVHKVLNQI TELVGRIHDG LWRGYSEKPI TDVVNIGIGG SFLGPELVSE ALLPYAQRGV 190 200 210 220 230 240 RCHYLANIDG SEFHELSANL RAETTLFIVS SKSFNTLETL KNAMAARTWY LAQGGSEAEL 250 260 270 280 290 300 YRHFIAVSSN KAAAVAFGIR EENIFPMWDW VGGRYSLWSA IGLPIALAIG TANFKELLSG 310 320 330 340 350 360 AYTMDQHFQT APFDKNMPVL LALLGVWYGN FWDANSHAIL PYDHYLRNIT KHLQQLDMES 370 380 390 400 410 420 NGKSVLQDGT PVKTDTGPVI WGGVGCNGQH AYHQLLHQGT QLIPADFIVP VVSFNPVADH 430 440 450 460 470 480 HQWLYANCLS QSQALMLGKT REEAEAELRA KGLNEADIEK LAPHKVIPGN RPSNTLVVER 490 500 510 520 530 540 ISPRRLGALV AMYEHKVFVQ SVIWGINAFD QWGVELGKEL GKSVYQRLVG SLEDSAEDGS 550 TQGLINYFRG KHRG

References

[1]

"Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440." Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H., Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M., Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F., Madupu R., Nelson W.C., White O. , Peterson J.D., Khouri H.M., Hance I., Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A., Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M. Environ. Microbiol. 4:799-808(2002) [PubMed: 12534463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE015451 Genomic DNA. Translation: AAN67427.1.
RefSeq	NP_743963.1.
3D structure databases
HSSP	HSSP built from PDB template 1IAT based on UniProtKB P06744.
ModBase	Search...
Protein-protein interaction databases
STRING	Q88LW9.
Genome annotation databases
GeneID	1043294.
GenomeReviews	Gene locus PP_1808 in contig AE015451_GR.
KEGG	ppu:PP_1808.
NMPDR	fig|160488.1.peg.1793.
TIGR	PP_1808.
Phylogenomic databases
HOGENOM	Q88LW9.
OMA	HDASTEG.
Enzyme and pathway databases
BioCyc	PPUT160488:PP_1808-MON.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI1_PSEPK

Accession

Primary (citable) accession number: Q88LW9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 23, 2003
Last sequence update:	May 23, 2003
Last modified:	November 3, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)