Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase 1

Gene

pgi1

Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase 1 (pgi1), Glucose-6-phosphate isomerase 2 (pgi2)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei359Proton donorBy similarity1
Active sitei390By similarity1
Active sitei518By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase 1 (EC:5.3.1.9)
Short name:
GPI 1
Alternative name(s):
Phosphoglucose isomerase 1
Short name:
PGI 1
Phosphohexose isomerase 1
Short name:
PHI 1
Gene namesi
Name:pgi1
Synonyms:pgi-1
Ordered Locus Names:PP_1808
OrganismiPseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000556 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001807111 – 554Glucose-6-phosphate isomerase 1Add BLAST554

Interactioni

Protein-protein interaction databases

STRINGi160488.PP_1808.

Structurei

3D structure databases

ProteinModelPortaliQ88LW9.
SMRiQ88LW9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiENOG4107QP8. Bacteria.
COG0166. LUCA.
HOGENOMiHOG000261370.
KOiK01810.
OMAiNNIGEDY.

Family and domain databases

CDDicd05015. SIS_PGI_1. 1 hit.
cd05016. SIS_PGI_2. 1 hit.
Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase. 1 hit.
InterProiView protein in InterPro
IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
IPR035476. SIS_PGI_1.
IPR035482. SIS_PGI_2.
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiView protein in Pfam
PF00342. PGI. 1 hit.
PRINTSiPR00662. G6PISOMERASE.
PROSITEiView protein in PROSITE
PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q88LW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFYRTPHDV TALPAWKALQ QHREAMRGFS MSEAFAADAK RFDQFSLSAC
60 70 80 90 100
GLFLDYSKNL ITEQSRDLLV NLANEVGLQD AIKSMFSGEI INASEGRPVL
110 120 130 140 150
HTALRRPVGD KLSVNGVNVM PEVHKVLNQI TELVGRIHDG LWRGYSEKPI
160 170 180 190 200
TDVVNIGIGG SFLGPELVSE ALLPYAQRGV RCHYLANIDG SEFHELSANL
210 220 230 240 250
RAETTLFIVS SKSFNTLETL KNAMAARTWY LAQGGSEAEL YRHFIAVSSN
260 270 280 290 300
KAAAVAFGIR EENIFPMWDW VGGRYSLWSA IGLPIALAIG TANFKELLSG
310 320 330 340 350
AYTMDQHFQT APFDKNMPVL LALLGVWYGN FWDANSHAIL PYDHYLRNIT
360 370 380 390 400
KHLQQLDMES NGKSVLQDGT PVKTDTGPVI WGGVGCNGQH AYHQLLHQGT
410 420 430 440 450
QLIPADFIVP VVSFNPVADH HQWLYANCLS QSQALMLGKT REEAEAELRA
460 470 480 490 500
KGLNEADIEK LAPHKVIPGN RPSNTLVVER ISPRRLGALV AMYEHKVFVQ
510 520 530 540 550
SVIWGINAFD QWGVELGKEL GKSVYQRLVG SLEDSAEDGS TQGLINYFRG

KHRG
Length:554
Mass (Da):61,384
Last modified:May 23, 2003 - v1
Checksum:i088DD58137B3C135
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA. Translation: AAN67427.1.
RefSeqiNP_743963.1. NC_002947.4.
WP_010952844.1. NC_002947.4.

Genome annotation databases

EnsemblBacteriaiAAN67427; AAN67427; PP_1808.
GeneIDi1043294.
KEGGippu:PP_1808.
PATRICifig|160488.4.peg.1907.

Similar proteinsi

Entry informationi

Entry nameiG6PI1_PSEPK
AccessioniPrimary (citable) accession number: Q88LW9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: May 23, 2003
Last modified: August 30, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families