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Q88LV4 (GCH11_PSEPK) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 1

EC=3.5.4.16
Alternative name(s):
GTP cyclohydrolase I 1
Short name=GTP-CH-I 1
Gene names
Name:folE1
Ordered Locus Names:PP_1823
OrganismPseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]
Taxonomic identifier160488 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length190 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP-Rule MF_00223

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP-Rule MF_00223

Subunit structure

Homopolymer By similarity. HAMAP-Rule MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 190190GTP cyclohydrolase 1 1 HAMAP-Rule MF_00223
PRO_0000119430

Sequences

Sequence LengthMass (Da)Tools
Q88LV4 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: E65550A866122653

FASTA19021,388
        10         20         30         40         50         60 
MRFFPTGRSM SLEQNYTEIL SQIGEDVSRE GLLDTPKRAA KAMKYLCRGY EQTLEEVTNN 

        70         80         90        100        110        120 
ALFSSDNSEM VLVRDIELYS MCEHHMLPFI GKAHVAYLPK GKVLGLSKVA RIVDMYARRL 

       130        140        150        160        170        180 
QIQENLSRQI AEAVQQVTGA AGVAVVVEAK HMCMMMRGVE KQNSTMITSV MLGEFRDNAA 

       190 
TRSEFLSLIK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015451 Genomic DNA. Translation: AAN67442.1.
RefSeqNP_743978.1. NC_002947.3.

3D structure databases

ProteinModelPortalQ88LV4.
SMRQ88LV4. Positions 18-190.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING160488.PP_1823.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN67442; AAN67442; PP_1823.
GeneID1043278.
KEGGppu:PP_1823.
PATRIC19941898. VBIPsePut30601_1923.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
HOGENOMHOG000221222.
KOK01495.
OMAPIIGRAW.
OrthoDBEOG6XHC8G.
ProtClustDBPRK09347.

Enzyme and pathway databases

BioCycPPUT160488:GIXO-1868-MONOMER.
UniPathwayUPA00848; UER00151.

Family and domain databases

HAMAPMF_00223. FolE.
InterProIPR001474. GTP_CycHdrlase_I.
IPR018234. GTP_CycHdrlase_I_CS.
IPR020602. GTP_CycHdrlase_I_dom.
[Graphical view]
PANTHERPTHR11109. PTHR11109. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. folE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGCH11_PSEPK
AccessionPrimary (citable) accession number: Q88LV4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways