ID   Q88L44_PSEPK            Unreviewed;       556 AA.
AC   Q88L44;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 118.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   OrderedLocusNames=PP_2091 {ECO:0000313|EMBL:AAN67705.1};
OS   Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS   / KT2440).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=160488 {ECO:0000313|EMBL:AAN67705.1, ECO:0000313|Proteomes:UP000000556};
RN   [1] {ECO:0000313|EMBL:AAN67705.1, ECO:0000313|Proteomes:UP000000556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440
RC   {ECO:0000313|Proteomes:UP000000556};
RX   PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA   Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA   Martins dos Santos V.A., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA   Brinkac L., Beanan M., DeBoy R.T., Daugherty S., Kolonay J., Madupu R.,
RA   Nelson W., White O., Peterson J., Khouri H., Hance I., Chris Lee P.,
RA   Holtzapple E., Scanlan D., Tran K., Moazzez A., Utterback T., Rizzo M.,
RA   Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D.,
RA   Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N.,
RA   Dusterhoft A., Tummler B., Fraser C.M.;
RT   "Complete genome sequence and comparative analysis of the metabolically
RT   versatile Pseudomonas putida KT2440.";
RL   Environ. Microbiol. 4:799-808(2002).
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DR   EMBL; AE015451; AAN67705.1; -; Genomic_DNA.
DR   RefSeq; NP_744241.1; NC_002947.4.
DR   RefSeq; WP_010953092.1; NC_002947.4.
DR   AlphaFoldDB; Q88L44; -.
DR   STRING; 160488.PP_2091; -.
DR   PaxDb; 160488-PP_2091; -.
DR   GeneID; 83681398; -.
DR   KEGG; ppu:PP_2091; -.
DR   PATRIC; fig|160488.4.peg.2205; -.
DR   eggNOG; COG0515; Bacteria.
DR   eggNOG; COG0631; Bacteria.
DR   HOGENOM; CLU_034273_0_0_6; -.
DR   OrthoDB; 9801841at2; -.
DR   PhylomeDB; Q88L44; -.
DR   BioCyc; PPUT160488:G1G01-2229-MONOMER; -.
DR   Proteomes; UP000000556; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00143; PP2Cc; 1.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   PANTHER; PTHR43895; CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED; 1.
DR   PANTHER; PTHR43895:SF168; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF13672; PP2C_2; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00332; PP2Cc; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS51746; PPM_2; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:AAN67705.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000556};
KW   Transferase {ECO:0000313|EMBL:AAN67705.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        534..554
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..228
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
FT   DOMAIN          225..527
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   556 AA;  62087 MW;  E1E69E8046DD5694 CRC64;
     MSLQLSFAQA SATGPRAENQ DALRLVTPAP ELAASKGYLF ALADGVSQCT DGGLAARASL
     QALALDYYAT PATWSVAQAL DRLLLAQNRW LRAQGSGQPL LTTLSALVLR GRRFTLAHVG
     DCRVYRWHEG NLQCLSEDHV WDQPGMQHVL KRALGLDQHL LVDYLEGELQ PGECFLLLSD
     GVWASLGEQH IQAVLREQTD LQLAADTLVA SAHLSGSKDN ASALLVQVEQ LGTANLGDTL
     AQLQQWPVPG PLREGQVIDG WQVETLHAHS RQSLLYKVRD SQNQPWLLKT LPTAREQEPG
     AAQGLLLEEW FLRRIAGRHF PELHAASQRQ HLYYVMREYP GQNLAALLAE QGPLPLPQWL
     EVARQLLQAV GVLHRRNLLH RDIKPDNLHL GRDGQLRLLD FGLAYCPGLS EDPLHELPGT
     PSYIAPEAFD GHPPSPRQDL YAVGVTLYHL LTGHYPYGEV EAFQRPRFGQ PVNAARYRPD
     LPEWLQHNLL QAVASDPAQR FETAEHWLLL LERGDRQELP SRPRPLLERE PLKVWRTLAL
     LSLLINLILL FTLLKG
//