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Q88IY7 (UPPP_PSEPK) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:PP_2862
OrganismPseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]
Taxonomic identifier160488 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length277 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 277277Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151182

Regions

Transmembrane44 – 6421Helical; Potential
Transmembrane86 – 10621Helical; Potential
Transmembrane110 – 13021Helical; Potential
Transmembrane184 – 20421Helical; Potential
Transmembrane215 – 23521Helical; Potential
Transmembrane250 – 27021Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q88IY7 [UniParc].

Last modified June 20, 2003. Version 1.
Checksum: 82BFB2A820D710EF

FASTA27730,730
        10         20         30         40         50         60 
MMDFWTAFQA IILGVVEGLT EFLPISSTGH QIIVADLIGF GGERAMAFNI IIQLAAILAV 

        70         80         90        100        110        120 
VWEFRSKIFE VVFGLTNQPK ARRFTGNLLL AFMPAVVLGV LFADLIHEYL FNPVTVAAAL 

       130        140        150        160        170        180 
VVGGVIMLWA ERREHRVEVD HVDDMRWSHA LKIGFIQCLA MIPGTSRSGS TIIGGLLFGL 

       190        200        210        220        230        240 
SRKAATEFSF FLAMPTMVGA AVYSGYKYRD LFQPGDLPVF ALGFVTSFIF AMIAVRALLK 

       250        260        270 
FIANHSYAAF AWYRIVFGLF ILATWQFGWV DWSTAHG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015451 Genomic DNA. Translation: AAN68470.1.
RefSeqNP_745006.1. NC_002947.3.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING160488.PP_2862.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN68470; AAN68470; PP_2862.
GeneID1042766.
KEGGppu:PP_2862.
PATRIC19944178. VBIPsePut30601_3034.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAWRKISSS.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycPPUT160488:GIXO-2938-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_PSEPK
AccessionPrimary (citable) accession number: Q88IY7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2003
Last sequence update: June 20, 2003
Last modified: May 14, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families