Reviewed, UniProtKB/Swiss-Prot Q88IS4 (MQO3_PSEPK)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase 3
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor] 3
    MQO 3

Gene names

Name:	mqo3
Synonyms:	mqo-3
Ordered Locus Names:	PP_2925

Organism

Pseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]

Taxonomic identifier

160488 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	539 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 539	539	Probable malate:quinone oxidoreductase 3 HAMAP MF_00212		PRO_0000128734

Sequences

	Sequence		Length	Mass (Da)
	Q88IS4-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 526AB47EF530CA77	FASTA	539	59,671
	10 20 30 40 50 60 MKITIKPKLA MAGLALAIGM LNAQAAETRK VDVLLVGGGI MSSTLAVWLN ELEPGWSMEM 70 80 90 100 110 120 VERLDKVAEE SSNGWNNAGT GHSALAELNY TPEKDGKIDI SKAVEINESF QVTRQFLAWQ 130 140 150 160 170 180 VKQGVLKNPH SFINTTPHMS FVWGDDNIRF LKKRYEALQA SPLFKPMQYS EDHEQIRKWV 190 200 210 220 230 240 PLMMEGRDPN QKLAVTWTPI GTDVNFGEIT RQYVGYLQTR PNFDLKLSSE VQDITRNDDG 250 260 270 280 290 300 SWHVEYKNLK NGSKAATDAR FLFIGAGGAA LPLLQKSGID EAKNYGGFPV GGSFLVTDNP 310 320 330 340 350 360 AIAQRHMAKA YGIAATGAPP MSVPHLDTRV LDGKRLILFG PFATFSTKFL KQGSLLDLLA 370 380 390 400 410 420 STSVHNAWPM VRVGVREFDL VQYLIGQVLQ SDDDRFEALR TYFPEAKKED WRLWQAGQRV 430 440 450 460 470 480 QIIKKDEALG GVLKLGTEVV TSRDGSIAGL LGASPGASTA APIMLDVLNK VFKNKVASPE 490 500 510 520 530 WQAKIKQIIP SYGIRLNDHP DQLEKEWAYT NEVLQLEPPV SPQRPESIRP ADSQGVASR

References

[1]

"Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440." Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H., Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M., Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F., Madupu R., Nelson W.C., White O. , Peterson J.D., Khouri H.M., Hance I., Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A., Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M. Environ. Microbiol. 4:799-808(2002) [PubMed: 12534463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015451 Genomic DNA. Translation: AAN68533.1.
RefSeq	NP_745069.1.
3D structure databases
SMR	Q88IS4. Positions 26-303.
ModBase	Search...
Protein-protein interaction databases
STRING	Q88IS4.
Genome annotation databases
GeneID	1042853.
GenomeReviews	Gene locus PP_2925 in contig AE015451_GR.
KEGG	ppu:PP_2925.
NMPDR	fig|160488.1.peg.2899.
TIGR	PP_2925.
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	GDDNIRF.
PhylomeDB	Q88IS4.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO3_PSEPK

Accession

Primary (citable) accession number: Q88IS4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	June 1, 2003
Last modified:	February 9, 2010
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)