ID   Q88EU0_PSEPK            Unreviewed;       563 AA.
AC   Q88EU0;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 126.
DE   SubName: Full=Sensor histidine kinase/response regulator {ECO:0000313|EMBL:AAN69941.1};
GN   OrderedLocusNames=PP_4363 {ECO:0000313|EMBL:AAN69941.1};
OS   Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS   / KT2440).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=160488 {ECO:0000313|EMBL:AAN69941.1, ECO:0000313|Proteomes:UP000000556};
RN   [1] {ECO:0000313|EMBL:AAN69941.1, ECO:0000313|Proteomes:UP000000556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440
RC   {ECO:0000313|Proteomes:UP000000556};
RX   PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA   Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA   Martins dos Santos V.A., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA   Brinkac L., Beanan M., DeBoy R.T., Daugherty S., Kolonay J., Madupu R.,
RA   Nelson W., White O., Peterson J., Khouri H., Hance I., Chris Lee P.,
RA   Holtzapple E., Scanlan D., Tran K., Moazzez A., Utterback T., Rizzo M.,
RA   Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D.,
RA   Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N.,
RA   Dusterhoft A., Tummler B., Fraser C.M.;
RT   "Complete genome sequence and comparative analysis of the metabolically
RT   versatile Pseudomonas putida KT2440.";
RL   Environ. Microbiol. 4:799-808(2002).
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DR   EMBL; AE015451; AAN69941.1; -; Genomic_DNA.
DR   RefSeq; NP_746477.1; NC_002947.4.
DR   RefSeq; WP_010955086.1; NC_002947.4.
DR   AlphaFoldDB; Q88EU0; -.
DR   STRING; 160488.PP_4363; -.
DR   PaxDb; 160488-PP_4363; -.
DR   GeneID; 83678927; -.
DR   KEGG; ppu:PP_4363; -.
DR   PATRIC; fig|160488.4.peg.4637; -.
DR   eggNOG; COG2208; Bacteria.
DR   eggNOG; COG3437; Bacteria.
DR   HOGENOM; CLU_000445_43_7_6; -.
DR   OrthoDB; 9811749at2; -.
DR   PhylomeDB; Q88EU0; -.
DR   BioCyc; PPUT160488:G1G01-4641-MONOMER; -.
DR   Proteomes; UP000000556; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR43156:SF13; PROTEIN ICFG; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:AAN69941.1};
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000556};
KW   Transferase {ECO:0000313|EMBL:AAN69941.1}.
FT   DOMAIN          8..124
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   MOD_RES         57
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   563 AA;  62118 MW;  912388C53E89CB07 CRC64;
     MPAEQALTVL VAEDSAVDRL LLAQIVRRQG HQVFTAENGE QAVALYLERR PQLVLLDALM
     PVMDGFEAAR QIKALAGEAL VPIIFLTSLN EEEGLVRCLE AGGDDFMAKP YSAVILAAKI
     RAMDRLRRLQ ATVLEQRDQI TRHHHHLLNE QRVAKAVFDK VAHSGCLSAP NIRYLQSPYA
     LFNGDLMLAA FTPAGDMRVL LGDFTGHGLP AAVGAMPMAE VFYGMTAKGY GMAQILREMN
     AKLKRILPVD MFCCALLLNL SMQRGSVEVW NGGMPDGYRL SVDGQVLSAL SSRHLPLGIL
     AAERFDDSTE VLPLAPGERL LLLSDGVIDT ADDQECLFGV QRLRAVLADN RDPVKLFDEL
     MLALERFGGQ PRDDISLCDI RMFTAEERVA APMIYSDSGR SSPLDWSLSF EVRGESLKRF
     NPVPYLVQLL QEIHGLRART GNLHSVLSEL YSNALEHGVL GLDSQLKRDV QGFTDYYQER
     ARRLGSLTEG FVSIDFKVEP HGGGGRLMIE VRDSGAGFDV QRVLARPSPD QGLSGRGLNL
     VRQLASDARW SEGGRCAHVE FVW
//