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Q88DF7 (PNCB_PSEPK) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:PP_4868
OrganismPseudomonas putida (strain KT2440) [Complete proteome] [HAMAP]
Taxonomic identifier160488 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence caution

The sequence AAN70437.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205839

Sequences

Sequence LengthMass (Da)Tools
Q88DF7 [UniParc].

Last modified July 5, 2005. Version 2.
Checksum: AD30738BE61C3089

FASTA40146,218
        10         20         30         40         50         60 
MSESAFAERI VHNLLDTDFY KLTMMQGVLH NYPDADVEWE FRCRNGEDLR PYLGEIRNQL 

        70         80         90        100        110        120 
ERLADLTLDD GQLAFLERIS FLKPDFLRFL RLFRFNLRYV HVGIENDQLF LRLKGPWLHV 

       130        140        150        160        170        180 
ILFEVPLLAI ISEVRNRNLH PHMRLAEARD QLYRKFDWLR AHASDDELAE LQVADFGTRR 

       190        200        210        220        230        240 
RFSSRVQEEV ARVLRDDFPG RFVGTSNVDL AWKLDIKPLG TMAHEWIMAH QQLGPRLIDS 

       250        260        270        280        290        300 
QIAALDCWVR EYRGLLGIAL TDCITMDAFL GDFDLYFAKL FDGLRHDSGE PVAWAEKAIA 

       310        320        330        340        350        360 
HYQKLGIDPM TKTLVFSDGL NLTRSLEIFR ALRGRINVSF GIGTNLTCDI PGVAPMNIVL 

       370        380        390        400 
KMTDCNGAPV AKISDEAAKT QCRDENFVAY MRHVFKVPSK E 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015451 Genomic DNA. Translation: AAN70437.1. Different initiation.
RefSeqNP_746973.1. NC_002947.3.

3D structure databases

ProteinModelPortalQ88DF7.
SMRQ88DF7. Positions 1-397.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING160488.PP_4868.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN70437; AAN70437; PP_4868.
GeneID1043392.
KEGGppu:PP_4868.
PATRIC19948538. VBIPsePut30601_5200.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycPPUT160488:GIXO-4962-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_PSEPK
AccessionPrimary (citable) accession number: Q88DF7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: July 5, 2005
Last modified: March 19, 2014
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways