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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPPUT160488:G1G01-5433-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:PP_5089
OrganismiPseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Taxonomic identifieri160488 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000556 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515931 – 578Arginine--tRNA ligaseAdd BLAST578

Proteomic databases

PRIDEiQ88CU1

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi160488.PP_5089

Structurei

3D structure databases

ProteinModelPortaliQ88CU1
SMRiQ88CU1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi127 – 137"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q88CU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDTIRQLIQ QALTQLVTDG VLPEGLSPAI QVENARDKTH GDFASNIAMM
60 70 80 90 100
LAKPAGMKPR DLAEKLINAL PASADISKVE IAGPGFLNFF QNTDALANRL
110 120 130 140 150
DAALADAHLG ARKAGPAQKV VIDMSAPNLA KEMHVGHLRS TIIGDSVARV
160 170 180 190 200
LEFLGDNVIR QNHVGDWGTQ FGMLMAYLQE NPITSDELSD LENFYRAAKK
210 220 230 240 250
RFDESEEFAT RARGLVVKLQ AGDPECLALW TRFKDISLSH CQKTYELLNV
260 270 280 290 300
KLTMADVMGE SAYNDDLANV VADLKAKGLL VEDQGAQCVF LEEFKNSDGD
310 320 330 340 350
PLPVIVQKAD GGYLYATTDL AAVRYRSNVL KADRALYFVD QRQALHFNQV
360 370 380 390 400
FEVARRAGFV GHPMQMEHMG FGTMNGADGR PFKTRDGGTV KLIDLLTEAK
410 420 430 440 450
ERAYALVKEK NPSLADDELR HIGEVVGIGA VKYADLSKHR TSDYSFNFEL
460 470 480 490 500
MLNFEGNTAP YLLYAYTRVA GVFRKLGKGF DEVDGKIVLQ AAHEQDLAAR
510 520 530 540 550
LAQFGEILNN VAEKGTPHVL CSYLYDLAGL FSSFYENCPI LAAETPSQQQ
560 570
SRLRLAALTG RTLKQGLELL GLETLERM
Length:578
Mass (Da):63,669
Last modified:June 1, 2003 - v1
Checksum:i3EB8E057F3D392E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015451 Genomic DNA Translation: AAN70654.1
RefSeqiNP_747190.1, NC_002947.4
WP_010955633.1, NC_002947.4

Genome annotation databases

EnsemblBacteriaiAAN70654; AAN70654; PP_5089
GeneIDi1041719
KEGGippu:PP_5089
PATRICifig|160488.4.peg.5432

Similar proteinsi

Entry informationi

Entry nameiSYR_PSEPK
AccessioniPrimary (citable) accession number: Q88CU1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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