ID   Q88CF9_PSEPK            Unreviewed;       951 AA.
AC   Q88CF9;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 96.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:AAN70787.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:AAN70787.1};
DE            EC=4.6.1.6 {ECO:0000313|EMBL:AAN70787.1};
GN   Name=cyaA {ECO:0000313|EMBL:AAN70787.1};
GN   OrderedLocusNames=PP_5222 {ECO:0000313|EMBL:AAN70787.1};
OS   Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS   / KT2440).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=160488 {ECO:0000313|EMBL:AAN70787.1, ECO:0000313|Proteomes:UP000000556};
RN   [1] {ECO:0000313|EMBL:AAN70787.1, ECO:0000313|Proteomes:UP000000556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440
RC   {ECO:0000313|Proteomes:UP000000556};
RX   PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA   Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA   Martins dos Santos V.A., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA   Brinkac L., Beanan M., DeBoy R.T., Daugherty S., Kolonay J., Madupu R.,
RA   Nelson W., White O., Peterson J., Khouri H., Hance I., Chris Lee P.,
RA   Holtzapple E., Scanlan D., Tran K., Moazzez A., Utterback T., Rizzo M.,
RA   Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D.,
RA   Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N.,
RA   Dusterhoft A., Tummler B., Fraser C.M.;
RT   "Complete genome sequence and comparative analysis of the metabolically
RT   versatile Pseudomonas putida KT2440.";
RL   Environ. Microbiol. 4:799-808(2002).
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DR   EMBL; AE015451; AAN70787.1; -; Genomic_DNA.
DR   RefSeq; NP_747323.1; NC_002947.4.
DR   RefSeq; WP_010955744.1; NC_002947.4.
DR   AlphaFoldDB; Q88CF9; -.
DR   STRING; 160488.PP_5222; -.
DR   PaxDb; 160488-PP_5222; -.
DR   GeneID; 83682963; -.
DR   KEGG; ppu:PP_5222; -.
DR   PATRIC; fig|160488.4.peg.5570; -.
DR   eggNOG; COG3072; Bacteria.
DR   HOGENOM; CLU_013280_0_0_6; -.
DR   OrthoDB; 5571448at2; -.
DR   PhylomeDB; Q88CF9; -.
DR   BioCyc; PPUT160488:G1G01-5572-MONOMER; -.
DR   Proteomes; UP000000556; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047805; F:cytidylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IEA:InterPro.
DR   InterPro; IPR000274; Adenylate_cyclase_1.
DR   InterPro; IPR024685; Adenylate_cyclase_1_N.
DR   PANTHER; PTHR38760; ADENYLATE CYCLASE; 1.
DR   PANTHER; PTHR38760:SF1; ADENYLATE CYCLASE; 1.
DR   Pfam; PF12633; Adenyl_cycl_N; 1.
DR   Pfam; PF01295; Adenylate_cycl; 1.
DR   PIRSF; PIRSF001444; Adenylate_cycl; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:AAN70787.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000556}.
FT   DOMAIN          20..216
FT                   /note="Adenylate cyclase class-I N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12633"
SQ   SEQUENCE   951 AA;  108384 MW;  571D31AD454DA650 CRC64;
     MNHPHEIRPD LDEGIDRKVL ATLRARFLHL NQGRLQRAKE GLSTRQQQVL SLLPLLFHVN
     HPLLPGYVSG STPAGVSAYE PSAELVADAQ RLARSFTYKA QHGNPPRPIH GLFLMGSLGS
     LAQAEHSDMD LWVCHAPGLP EQLLGELRRK CQLLEAWAAS LGAEAHFFLI DTQGFAQGQR
     DGQLGSDDCG TTQHYLLLDE FYRTTLWLAG RTPLWWLVPV YEEHNYYSYT QTLLSKRFIR
     SQEALDLGNL AHIPPGEFVG AGLWQLFKGI DSPYKSLLKL LLTEAYASEH PAVRCLSLDY
     KQAVFANQLD LDELDPYVMV YRRIERYLLQ RGETARLELV RRSLYLKVNK KLSDQGRSHG
     WQRRLLQRLA DEWGWDQRQL ALLDSRSQWK VQQVAVERRE LVAELNLSYR FLSQFARTQN
     ASSRADQRDL NVLGRRLYAA FERRAGKVEV INPGIAPDLA EDTLTLVQAP NRKEPGSYHW
     ELYSGNLSTH EVQHFSPMKR CRELLELLTW AHRNGVIDSS TRMALHPGAS DLGEFELFNL
     LGCLRQSIPL PLPTVSEVRL LQPSVADEVL LLVNVGVDPL RHHRDLNVLM TTERTDALSY
     AGVRENLVLT LDQVTVNSWN EVLVQRYDGE HALVRCLRDF LNSPAQRGHR PRVRVRCFCQ
     SRAQPIGQRV EEIFDTVQLL RDQGLHHRYL LQVAQHTHVL ELLPEHVSLT TLAEHEALLA
     YLGEERSVYS PLYLDANALQ DHDLRLVLEQ GRPACIQVFY RLQGGWADVY VLDEYNALWQ
     QRLPLHDEAH LLLPLQRFLR SVVMRRDARL PLDSLRPASL DIHFAQLLPT GPGKARSIEP
     RLAPAEGSDQ PYYEVQAIIQ AGVAGVAHVT LYCDQQEFSE LEHGEQLYAV VARQIIGQRR
     GAERYRCYIT DLDLSELLDD RLGATQVYLS YKRVLEQALN EGLEQVLAQG A
//