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Protein

Aminomethyltransferase

Gene

gcvT

Organism
Pseudomonas syringae pv. tomato (strain DC3000)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciPSYR223283:GJIX-312-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Alternative name(s):
Glycine cleavage system T proteinUniRule annotation
Gene namesi
Name:gcvTUniRule annotation
Synonyms:gcvT-1
Ordered Locus Names:PSPTO_0316
OrganismiPseudomonas syringae pv. tomato (strain DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002515 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 360360AminomethyltransferasePRO_0000122588Add
BLAST

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Protein-protein interaction databases

STRINGi223283.PSPTO_0316.

Structurei

3D structure databases

ProteinModelPortaliQ88AS0.
SMRiQ88AS0. Positions 4-359.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0404.
HOGENOMiHOG000239381.
KOiK00605.
OMAiMAWSIAW.
OrthoDBiEOG6T1WS5.
PhylomeDBiQ88AS0.

Family and domain databases

Gene3Di2.40.30.110. 1 hit.
3.30.1360.120. 1 hit.
HAMAPiMF_00259. GcvT.
InterProiIPR006223. GCS_T.
IPR022903. GCS_T_bac.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR029043. GcvT/YgfZ_C.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PANTHERiPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamiPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006487. GcvT. 1 hit.
SUPFAMiSSF101790. SSF101790. 1 hit.
TIGRFAMsiTIGR00528. gcvT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q88AS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQRTPLFDL HLALGAKMVD FGGWDMPLHY GSQVEEHHQV RRDCGVFDVS
60 70 80 90 100
HMNVIDVLGR EAKAWLRRLL ANDVDKLKTP GRALYSAMLD EQAGVIDDMI
110 120 130 140 150
VYLTADGYRL VVNAATGAKD LAWMQSQLGD FDVQLLARSE MAMLAIQGPQ
160 170 180 190 200
ARNRIAQLVS SARAELIRQL KPFEGLDDGD WFIARTGYTG EDGLEIMLPA
210 220 230 240 250
DEAQRFFNEL VGAGISPIGL GARDTLRLEA GMNLYGQDIG EHVSPLASNM
260 270 280 290 300
AWSIAWEPAE RDFIGRQALE SERAEGTAFK LVGLVLEERG VLRAHQVVRV
310 320 330 340 350
AEIGEGEITS GSFSPTLSKS IALARVPMAT ADRAEVEIRG KWYPVRVVQP
360
AFVRHGKTLI
Length:360
Mass (Da):39,665
Last modified:May 30, 2003 - v1
Checksum:iB3794951DC3A1E0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA. Translation: AAO53861.1.
RefSeqiNP_790166.1. NC_004578.1.
WP_005763440.1. NC_004578.1.

Genome annotation databases

EnsemblBacteriaiAAO53861; AAO53861; PSPTO_0316.
GeneIDi1181925.
KEGGipst:PSPTO_0316.
PATRICi19991802. VBIPseSyr93040_0329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA. Translation: AAO53861.1.
RefSeqiNP_790166.1. NC_004578.1.
WP_005763440.1. NC_004578.1.

3D structure databases

ProteinModelPortaliQ88AS0.
SMRiQ88AS0. Positions 4-359.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi223283.PSPTO_0316.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO53861; AAO53861; PSPTO_0316.
GeneIDi1181925.
KEGGipst:PSPTO_0316.
PATRICi19991802. VBIPseSyr93040_0329.

Phylogenomic databases

eggNOGiCOG0404.
HOGENOMiHOG000239381.
KOiK00605.
OMAiMAWSIAW.
OrthoDBiEOG6T1WS5.
PhylomeDBiQ88AS0.

Enzyme and pathway databases

BioCyciPSYR223283:GJIX-312-MONOMER.

Family and domain databases

Gene3Di2.40.30.110. 1 hit.
3.30.1360.120. 1 hit.
HAMAPiMF_00259. GcvT.
InterProiIPR006223. GCS_T.
IPR022903. GCS_T_bac.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR029043. GcvT/YgfZ_C.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PANTHERiPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamiPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006487. GcvT. 1 hit.
SUPFAMiSSF101790. SSF101790. 1 hit.
TIGRFAMsiTIGR00528. gcvT. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DC3000.

Entry informationi

Entry nameiGCST_PSESM
AccessioniPrimary (citable) accession number: Q88AS0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: May 30, 2003
Last modified: May 27, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.