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Q88AS0 (GCST_PSESM) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aminomethyltransferase

EC=2.1.2.10
Alternative name(s):
Glycine cleavage system T protein
Gene names
Name:gcvT
Synonyms:gcvT-1
Ordered Locus Names:PSPTO_0316
OrganismPseudomonas syringae pv. tomato (strain DC3000) [Complete proteome] [HAMAP]
Taxonomic identifier223283 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP-Rule MF_00259

Catalytic activity

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP-Rule MF_00259

Subunit structure

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.

Sequence similarities

Belongs to the GcvT family.

Ontologies

Keywords
   Molecular functionAminotransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycine catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_functionaminomethyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

transaminase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 360360Aminomethyltransferase HAMAP-Rule MF_00259
PRO_0000122588

Sequences

Sequence LengthMass (Da)Tools
Q88AS0 [UniParc].

Last modified May 30, 2003. Version 1.
Checksum: B3794951DC3A1E0D

FASTA36039,665
        10         20         30         40         50         60 
MGQRTPLFDL HLALGAKMVD FGGWDMPLHY GSQVEEHHQV RRDCGVFDVS HMNVIDVLGR 

        70         80         90        100        110        120 
EAKAWLRRLL ANDVDKLKTP GRALYSAMLD EQAGVIDDMI VYLTADGYRL VVNAATGAKD 

       130        140        150        160        170        180 
LAWMQSQLGD FDVQLLARSE MAMLAIQGPQ ARNRIAQLVS SARAELIRQL KPFEGLDDGD 

       190        200        210        220        230        240 
WFIARTGYTG EDGLEIMLPA DEAQRFFNEL VGAGISPIGL GARDTLRLEA GMNLYGQDIG 

       250        260        270        280        290        300 
EHVSPLASNM AWSIAWEPAE RDFIGRQALE SERAEGTAFK LVGLVLEERG VLRAHQVVRV 

       310        320        330        340        350        360 
AEIGEGEITS GSFSPTLSKS IALARVPMAT ADRAEVEIRG KWYPVRVVQP AFVRHGKTLI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016853 Genomic DNA. Translation: AAO53861.1.
RefSeqNP_790166.1. NC_004578.1.

3D structure databases

ProteinModelPortalQ88AS0.
SMRQ88AS0. Positions 4-359.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING223283.PSPTO_0316.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO53861; AAO53861; PSPTO_0316.
GeneID1181925.
KEGGpst:PSPTO_0316.
PATRIC19991802. VBIPseSyr93040_0329.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0404.
HOGENOMHOG000239381.
KOK00605.
OMAMAWSIAW.
OrthoDBEOG6T1WS5.
ProtClustDBPRK00389.

Enzyme and pathway databases

BioCycPSYR223283:GJIX-312-MONOMER.

Family and domain databases

Gene3D2.40.30.110. 1 hit.
3.30.1360.120. 1 hit.
HAMAPMF_00259. GcvT.
InterProIPR006223. GCS_T.
IPR022903. GCS_T_bac.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PANTHERPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFPIRSF006487. GcvT. 1 hit.
TIGRFAMsTIGR00528. gcvT. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGCST_PSESM
AccessionPrimary (citable) accession number: Q88AS0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: May 30, 2003
Last modified: April 16, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families