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Protein

Aminomethyltransferase

Gene

gcvT

Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase

Enzyme and pathway databases

BioCyciPSYR223283:G1G0D-312-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Alternative name(s):
Glycine cleavage system T proteinUniRule annotation
Gene namesi
Name:gcvTUniRule annotation
Synonyms:gcvT-1
Ordered Locus Names:PSPTO_0316
OrganismiPseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002515 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001225881 – 360AminomethyltransferaseAdd BLAST360

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Protein-protein interaction databases

STRINGi223283.PSPTO_0316

Structurei

3D structure databases

ProteinModelPortaliQ88AS0
SMRiQ88AS0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D43 Bacteria
COG0404 LUCA
HOGENOMiHOG000239381
KOiK00605
OMAiYPLHGQD
OrthoDBiPOG091H04FV
PhylomeDBiQ88AS0

Family and domain databases

Gene3Di3.30.1360.120, 2 hits
HAMAPiMF_00259 GcvT, 1 hit
InterProiView protein in InterPro
IPR006223 GCS_T
IPR022903 GCS_T_bac
IPR028896 GCST/YgfZ/DmdA
IPR013977 GCV_T_C
IPR006222 GCV_T_N
IPR029043 GcvT/YgfZ_C
IPR027266 TrmE/GcvT_dom1
PfamiView protein in Pfam
PF01571 GCV_T, 1 hit
PF08669 GCV_T_C, 1 hit
PIRSFiPIRSF006487 GcvT, 1 hit
SUPFAMiSSF101790 SSF101790, 1 hit
TIGRFAMsiTIGR00528 gcvT, 1 hit

Sequencei

Sequence statusi: Complete.

Q88AS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQRTPLFDL HLALGAKMVD FGGWDMPLHY GSQVEEHHQV RRDCGVFDVS
60 70 80 90 100
HMNVIDVLGR EAKAWLRRLL ANDVDKLKTP GRALYSAMLD EQAGVIDDMI
110 120 130 140 150
VYLTADGYRL VVNAATGAKD LAWMQSQLGD FDVQLLARSE MAMLAIQGPQ
160 170 180 190 200
ARNRIAQLVS SARAELIRQL KPFEGLDDGD WFIARTGYTG EDGLEIMLPA
210 220 230 240 250
DEAQRFFNEL VGAGISPIGL GARDTLRLEA GMNLYGQDIG EHVSPLASNM
260 270 280 290 300
AWSIAWEPAE RDFIGRQALE SERAEGTAFK LVGLVLEERG VLRAHQVVRV
310 320 330 340 350
AEIGEGEITS GSFSPTLSKS IALARVPMAT ADRAEVEIRG KWYPVRVVQP
360
AFVRHGKTLI
Length:360
Mass (Da):39,665
Last modified:May 30, 2003 - v1
Checksum:iB3794951DC3A1E0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA Translation: AAO53861.1
RefSeqiNP_790166.1, NC_004578.1
WP_005763440.1, NC_004578.1

Genome annotation databases

EnsemblBacteriaiAAO53861; AAO53861; PSPTO_0316
GeneIDi1181925
KEGGipst:PSPTO_0316
PATRICifig|223283.9.peg.329

Similar proteinsi

Entry informationi

Entry nameiGCST_PSESM
AccessioniPrimary (citable) accession number: Q88AS0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: May 30, 2003
Last modified: March 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health