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Q88AS0

- GCST_PSESM

UniProt

Q88AS0 - GCST_PSESM

Protein

Aminomethyltransferase

Gene

gcvT

Organism
Pseudomonas syringae pv. tomato (strain DC3000)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (30 May 2003)
      Previous versions | rss
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    Functioni

    The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

    Catalytic activityi

    [Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

    GO - Molecular functioni

    1. aminomethyltransferase activity Source: UniProtKB-EC
    2. transaminase activity Source: UniProtKB-KW

    GO - Biological processi

    1. glycine catabolic process Source: InterPro

    Keywords - Molecular functioni

    Aminotransferase, Transferase

    Enzyme and pathway databases

    BioCyciPSYR223283:GJIX-312-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
    Alternative name(s):
    Glycine cleavage system T proteinUniRule annotation
    Gene namesi
    Name:gcvTUniRule annotation
    Synonyms:gcvT-1
    Ordered Locus Names:PSPTO_0316
    OrganismiPseudomonas syringae pv. tomato (strain DC3000)
    Taxonomic identifieri223283 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002515: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 360360AminomethyltransferasePRO_0000122588Add
    BLAST

    Interactioni

    Subunit structurei

    The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

    Protein-protein interaction databases

    STRINGi223283.PSPTO_0316.

    Structurei

    3D structure databases

    ProteinModelPortaliQ88AS0.
    SMRiQ88AS0. Positions 4-359.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GcvT family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0404.
    HOGENOMiHOG000239381.
    KOiK00605.
    OMAiIAYLHAD.
    OrthoDBiEOG6T1WS5.
    PhylomeDBiQ88AS0.

    Family and domain databases

    Gene3Di2.40.30.110. 1 hit.
    3.30.1360.120. 1 hit.
    HAMAPiMF_00259. GcvT.
    InterProiIPR006223. GCS_T.
    IPR022903. GCS_T_bac.
    IPR028896. GCST/DmdA.
    IPR013977. GCV_T_C.
    IPR006222. GCV_T_N.
    IPR029043. GcvT/YgfZ_C.
    IPR027266. TrmE/GcvT_dom1.
    [Graphical view]
    PANTHERiPTHR13847:SF5. PTHR13847:SF5. 1 hit.
    PfamiPF01571. GCV_T. 1 hit.
    PF08669. GCV_T_C. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006487. GcvT. 1 hit.
    SUPFAMiSSF101790. SSF101790. 1 hit.
    TIGRFAMsiTIGR00528. gcvT. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q88AS0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGQRTPLFDL HLALGAKMVD FGGWDMPLHY GSQVEEHHQV RRDCGVFDVS    50
    HMNVIDVLGR EAKAWLRRLL ANDVDKLKTP GRALYSAMLD EQAGVIDDMI 100
    VYLTADGYRL VVNAATGAKD LAWMQSQLGD FDVQLLARSE MAMLAIQGPQ 150
    ARNRIAQLVS SARAELIRQL KPFEGLDDGD WFIARTGYTG EDGLEIMLPA 200
    DEAQRFFNEL VGAGISPIGL GARDTLRLEA GMNLYGQDIG EHVSPLASNM 250
    AWSIAWEPAE RDFIGRQALE SERAEGTAFK LVGLVLEERG VLRAHQVVRV 300
    AEIGEGEITS GSFSPTLSKS IALARVPMAT ADRAEVEIRG KWYPVRVVQP 350
    AFVRHGKTLI 360
    Length:360
    Mass (Da):39,665
    Last modified:May 30, 2003 - v1
    Checksum:iB3794951DC3A1E0D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016853 Genomic DNA. Translation: AAO53861.1.
    RefSeqiNP_790166.1. NC_004578.1.

    Genome annotation databases

    EnsemblBacteriaiAAO53861; AAO53861; PSPTO_0316.
    GeneIDi1181925.
    KEGGipst:PSPTO_0316.
    PATRICi19991802. VBIPseSyr93040_0329.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016853 Genomic DNA. Translation: AAO53861.1 .
    RefSeqi NP_790166.1. NC_004578.1.

    3D structure databases

    ProteinModelPortali Q88AS0.
    SMRi Q88AS0. Positions 4-359.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 223283.PSPTO_0316.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO53861 ; AAO53861 ; PSPTO_0316 .
    GeneIDi 1181925.
    KEGGi pst:PSPTO_0316.
    PATRICi 19991802. VBIPseSyr93040_0329.

    Phylogenomic databases

    eggNOGi COG0404.
    HOGENOMi HOG000239381.
    KOi K00605.
    OMAi IAYLHAD.
    OrthoDBi EOG6T1WS5.
    PhylomeDBi Q88AS0.

    Enzyme and pathway databases

    BioCyci PSYR223283:GJIX-312-MONOMER.

    Family and domain databases

    Gene3Di 2.40.30.110. 1 hit.
    3.30.1360.120. 1 hit.
    HAMAPi MF_00259. GcvT.
    InterProi IPR006223. GCS_T.
    IPR022903. GCS_T_bac.
    IPR028896. GCST/DmdA.
    IPR013977. GCV_T_C.
    IPR006222. GCV_T_N.
    IPR029043. GcvT/YgfZ_C.
    IPR027266. TrmE/GcvT_dom1.
    [Graphical view ]
    PANTHERi PTHR13847:SF5. PTHR13847:SF5. 1 hit.
    Pfami PF01571. GCV_T. 1 hit.
    PF08669. GCV_T_C. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006487. GcvT. 1 hit.
    SUPFAMi SSF101790. SSF101790. 1 hit.
    TIGRFAMsi TIGR00528. gcvT. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DC3000.

    Entry informationi

    Entry nameiGCST_PSESM
    AccessioniPrimary (citable) accession number: Q88AS0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2003
    Last sequence update: May 30, 2003
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3