Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q887Q9

- ALGA_PSESM

UniProt

Q887Q9 - ALGA_PSESM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alginate biosynthesis protein AlgA

Gene

algA

Organism
Pseudomonas syringae pv. tomato (strain DC3000)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity).By similarity

Catalytic activityi

D-mannose 6-phosphate = D-fructose 6-phosphate.
GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.

Cofactori

Cobalt (for PMI).By similarity

Pathwayi

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-KW
  2. mannose-1-phosphate guanylyltransferase activity Source: UniProtKB-EC
  3. mannose-6-phosphate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. alginic acid biosynthetic process Source: UniProtKB-KW
  2. GDP-mannose biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase, Nucleotidyltransferase, Transferase

Keywords - Biological processi

Alginate biosynthesis

Keywords - Ligandi

Cobalt, GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPSYR223283:GJIX-1257-MONOMER.
UniPathwayiUPA00126; UER00423.
UPA00126; UER00930.

Names & Taxonomyi

Protein namesi
Recommended name:
Alginate biosynthesis protein AlgA
Including the following 2 domains:
Mannose-6-phosphate isomerase (EC:5.3.1.8)
Alternative name(s):
Phosphohexomutase
Phosphomannose isomerase
Short name:
PMI
Mannose-1-phosphate guanylyltransferase (EC:2.7.7.13)
Alternative name(s):
GDP-mannose pyrophosphorylase
Short name:
GMP
Short name:
GMPP
GTP--mannose-1-phosphate guanylyltransferase
Gene namesi
Name:algA
Ordered Locus Names:PSPTO_1232
OrganismiPseudomonas syringae pv. tomato (strain DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002515: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 483483Alginate biosynthesis protein AlgAPRO_0000194251Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi223283.PSPTO_1232.

Structurei

3D structure databases

ProteinModelPortaliQ887Q9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0662.
HOGENOMiHOG000153549.
KOiK16011.
OMAiELKKHDP.
OrthoDBiEOG6X3W6T.
PhylomeDBiQ887Q9.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
3.90.550.10. 1 hit.
InterProiIPR006375. Man1P_GuaTrfase/Man6P_Isoase.
IPR001538. Man6P_isomerase-2_C.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF01050. MannoseP_isomer. 1 hit.
PF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51182. SSF51182. 1 hit.
SSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01479. GMP_PMI. 1 hit.

Sequencei

Sequence statusi: Complete.

Q887Q9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIPVILSGGS GSRLWPLSRK QFPKQFLALT GEHTLFQQTL QRLVFEGMQE
60 70 80 90 100
PIVVCNKDHR FIVNEQLAAL NLETQAILME PFGRNTAPAV ALTAMKLVNE
110 120 130 140 150
GNDGLMLVLP ADHVIEDQKA LQRALALATV TAERGEMVLF GVPANKPETG
160 170 180 190 200
YGYIKSTADA LLPEGVSRVS QFVEKPDEKR AKEFVEAGGY YWNSGMFLFR
210 220 230 240 250
ASRFLEELKK HDPDIYDTCL LTLERSVQDG DALEIDASTF ACCPDNSIDY
260 270 280 290 300
AVMEKTQRAC VVPLSAGWSD VGCWSSLWEV NAKDAHGNVT KGDVVIQDSR
310 320 330 340 350
NCMIHGNGKL VSVIGLDNIV VVETKDAMMI AHKDKVQGVK QMVATLNEQG
360 370 380 390 400
RTETQNHLEV YRPWGSYDSV DMGGRFQVKR ISVKPGACLS LQMHHHRAEH
410 420 430 440 450
WIVVSGTAQV TCDENVFLLT ENQSTYIPIA SVHRLRNPGK IPLEIIEVQS
460 470 480
GSYLGEDDIE RFEDIYGRSN ALEAGVKTQT IAR
Length:483
Mass (Da):53,563
Last modified:June 1, 2003 - v1
Checksum:iB9EFCA39C452FE44
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016853 Genomic DNA. Translation: AAO54757.1.
RefSeqiNP_791062.1. NC_004578.1.

Genome annotation databases

EnsemblBacteriaiAAO54757; AAO54757; PSPTO_1232.
GeneIDi1182868.
KEGGipst:PSPTO_1232.
PATRICi19993704. VBIPseSyr93040_1253.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016853 Genomic DNA. Translation: AAO54757.1 .
RefSeqi NP_791062.1. NC_004578.1.

3D structure databases

ProteinModelPortali Q887Q9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 223283.PSPTO_1232.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO54757 ; AAO54757 ; PSPTO_1232 .
GeneIDi 1182868.
KEGGi pst:PSPTO_1232.
PATRICi 19993704. VBIPseSyr93040_1253.

Phylogenomic databases

eggNOGi COG0662.
HOGENOMi HOG000153549.
KOi K16011.
OMAi ELKKHDP.
OrthoDBi EOG6X3W6T.
PhylomeDBi Q887Q9.

Enzyme and pathway databases

UniPathwayi UPA00126 ; UER00423 .
UPA00126 ; UER00930 .
BioCyci PSYR223283:GJIX-1257-MONOMER.

Family and domain databases

Gene3Di 2.60.120.10. 1 hit.
3.90.550.10. 1 hit.
InterProi IPR006375. Man1P_GuaTrfase/Man6P_Isoase.
IPR001538. Man6P_isomerase-2_C.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view ]
Pfami PF01050. MannoseP_isomer. 1 hit.
PF00483. NTP_transferase. 1 hit.
[Graphical view ]
SUPFAMi SSF51182. SSF51182. 1 hit.
SSF53448. SSF53448. 1 hit.
TIGRFAMsi TIGR01479. GMP_PMI. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DC3000.

Entry informationi

Entry nameiALGA_PSESM
AccessioniPrimary (citable) accession number: Q887Q9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: June 1, 2003
Last modified: October 1, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Multifunctional enzyme, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3