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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Pseudomonas syringae pv. tomato (strain DC3000)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciPSYR223283:GJIX-1473-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:PSPTO_1446
OrganismiPseudomonas syringae pv. tomato (strain DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002515 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 459459Exodeoxyribonuclease 7 large subunitPRO_0000197868Add
BLAST

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi223283.PSPTO_1446.

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229265.
KOiK03601.
OMAiVTYKENT.
OrthoDBiEOG64R65J.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q886X9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKDPFARLG LDREVLTVSQ LNGRARVLLE DVFSSIWVEG EISNLSRPAS
60 70 80 90 100
GHVYFTLKDS GAQVRCALFR QSAARVRQAL KDGLQVKVRG KVSLFEGRGD
110 120 130 140 150
YQLILDTVEP AGDGALRLAF DALKAKLSDE GLFSADRKVA LPLHPQRIGI
160 170 180 190 200
ISSPTGAVIR DIISVFRRRA PRVELTLIPT AVQGREAINQ IVRALKLADA
210 220 230 240 250
RGFDALILAR GGGSLEDLWC FNEEAVARAI DACVTPIVSA VGHETDVSIS
260 270 280 290 300
DFVADVRAPT PSAAAELLAP DSSDLHRRVD NLHRRLVSRM QDRLMRERLR
310 320 330 340 350
LEGISRRLRH PGERLRQQSQ RLDDLDMRLR RAFEQSMHKK QVRLAHMESR
360 370 380 390 400
LTAQHPGRTL AFLRQRLDAL AERLPRAIRE QIKVRKLQLQ SQMQTLNVVS
410 420 430 440 450
PLATLGRGYS ILLDERGHAI RNAAQTQPGQ RLTARLGEGE LQVRVEDNHL

TPVTLSLLD
Length:459
Mass (Da):51,243
Last modified:June 6, 2003 - v1
Checksum:i9F18AD78B909B2B0
GO

Sequence cautioni

The sequence AAO54967.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA. Translation: AAO54967.1. Different initiation.
RefSeqiNP_791272.1. NC_004578.1.

Genome annotation databases

EnsemblBacteriaiAAO54967; AAO54967; PSPTO_1446.
GeneIDi1183083.
KEGGipst:PSPTO_1446.
PATRICi19994132. VBIPseSyr93040_1466.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA. Translation: AAO54967.1. Different initiation.
RefSeqiNP_791272.1. NC_004578.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi223283.PSPTO_1446.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO54967; AAO54967; PSPTO_1446.
GeneIDi1183083.
KEGGipst:PSPTO_1446.
PATRICi19994132. VBIPseSyr93040_1466.

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229265.
KOiK03601.
OMAiVTYKENT.
OrthoDBiEOG64R65J.

Enzyme and pathway databases

BioCyciPSYR223283:GJIX-1473-MONOMER.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DC3000.

Entry informationi

Entry nameiEX7L_PSESM
AccessioniPrimary (citable) accession number: Q886X9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 6, 2003
Last sequence update: June 6, 2003
Last modified: November 11, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.