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Protein

Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon

Gene

cheB3

Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR.UniRule annotation

Catalytic activityi

Protein L-glutamate O5-methyl ester + H2O = protein L-glutamate + methanol.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei159UniRule annotation1
Active sitei186UniRule annotation1
Active sitei279UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processChemotaxis

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis response regulator protein-glutamate methylesterase of group 3 operonUniRule annotation (EC:3.1.1.61UniRule annotation)
Gene namesi
Name:cheB3UniRule annotation
Ordered Locus Names:PSPTO_1498
OrganismiPseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002515 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001580161 – 336Chemotaxis response regulator protein-glutamate methylesterase of group 3 operonAdd BLAST336

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei534-aspartylphosphateUniRule annotation1

Post-translational modificationi

Phosphorylated by CheA. Phosphorylation suppresses the inhibitory activity of the N-terminal domain.UniRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi223283.PSPTO_1498.

Structurei

3D structure databases

ProteinModelPortaliQ886S8.
SMRiQ886S8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 119Response regulatoryPROSITE-ProRule annotationAdd BLAST118
Domaini147 – 336CheB-type methylesteraseUniRule annotationAdd BLAST190

Domaini

The N-terminal regulatory domain inhibits the activity of the C-terminal effector domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMP. Bacteria.
COG2201. LUCA.
HOGENOMiHOG000151424.
KOiK13491.
OMAiAMVKIRQ.
OrthoDBiPOG091H045J.
PhylomeDBiQ886S8.

Family and domain databases

CDDicd16432. CheB_Rec. 1 hit.
cd00156. REC. 1 hit.
Gene3Di3.40.50.180. 1 hit.
HAMAPiMF_00099. CheB_methylest. 1 hit.
InterProiView protein in InterPro
IPR035909. CheB_C.
IPR011006. CheY-like_superfamily.
IPR008248. Sig_transdc_resp-reg_CheB.
IPR000673. Sig_transdc_resp-reg_Me-estase.
IPR001789. Sig_transdc_resp-reg_receiver.
PfamiView protein in Pfam
PF01339. CheB_methylest. 1 hit.
PF00072. Response_reg. 1 hit.
PIRSFiPIRSF000876. RR_chemtxs_CheB. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SUPFAMiSSF52172. SSF52172. 1 hit.
SSF52738. SSF52738. 1 hit.
PROSITEiView protein in PROSITE
PS50122. CHEB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q886S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIAIVNDMP MAIEALRRAL AFEPAHQVIW VAANGADAVQ RSIEQTPDLI
60 70 80 90 100
LMDLIMPVMD GVEATRRIMA ETPCAIVIVT VDREQNMRRV FEAMGHGALD
110 120 130 140 150
VVDTPAIGGP NPREAAAPLL RKILNIDWLM GQRVGRERVV TTSRSEVSRR
160 170 180 190 200
DRLVAIGSSA GGPAALEILL KGLPENFPAA IVLVQHVDQV FAAGMAEWLC
210 220 230 240 250
SASGMPVRLA KEGETPQVGV VLLAGTNHHI RLLKDGTLAY TAEPVNEVYR
260 270 280 290 300
PSIDVFFESV TRYWTGEAVG VLLTGMGRDG AQGLKAMRER GFLTIAQDQA
310 320 330
SSAVYGMPKA AAAIDAAVEI RPLHTIAPRL MEVFTQ
Length:336
Mass (Da):36,315
Last modified:June 1, 2003 - v1
Checksum:i9AC6962B34734D9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA. Translation: AAO55019.1.
RefSeqiNP_791324.1. NC_004578.1.
WP_005765912.1. NC_004578.1.

Genome annotation databases

EnsemblBacteriaiAAO55019; AAO55019; PSPTO_1498.
GeneIDi1183135.
KEGGipst:PSPTO_1498.
PATRICifig|223283.9.peg.1519.

Similar proteinsi

Entry informationi

Entry nameiCHEB3_PSESM
AccessioniPrimary (citable) accession number: Q886S8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: June 1, 2003
Last modified: November 22, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome