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Q886N0

- LPXB_PSESM

UniProt

Q886N0 - LPXB_PSESM

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Protein

Lipid-A-disaccharide synthase

Gene
lpxB, PSPTO_1547
Organism
Pseudomonas syringae pv. tomato (strain DC3000)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciPSYR223283:GJIX-1575-MONOMER.
UniPathwayiUPA00359; UER00481.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthase (EC:2.4.1.182)
Gene namesi
Name:lpxB
Ordered Locus Names:PSPTO_1547
OrganismiPseudomonas syringae pv. tomato (strain DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002515: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 380380Lipid-A-disaccharide synthaseUniRule annotationPRO_0000190179Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi223283.PSPTO_1547.

Structurei

3D structure databases

ProteinModelPortaliQ886N0.

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.

Phylogenomic databases

eggNOGiCOG0763.
HOGENOMiHOG000018004.
KOiK00748.
OMAiVSPITYR.
OrthoDBiEOG6FBWZR.
PhylomeDBiQ886N0.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q886N0-1 [UniParc]FASTAAdd to Basket

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MTSPLRIALV AGEASGDILG SGLMRALKAR HPDVRFIGVG GPLMEAEGMQ    50
SYFPMERLSV MGLVEVLGRL RELLARRKLL VQTLIDEKPD VFIGIDAPDF 100
TLNIELQLRR AGIKTVHYVS PSVWAWRQKR VLKIREGCDL MLTLLPFEAR 150
FYEEKGVPVR FVGHPLADTI PLESDRGATR AELGLSVDGP VVALMPGSRG 200
GEVGRLGALF FDAAERLLVE RPGLRFVLPC ASPQRRAQVE QLLQGRDLPI 250
TLLDGRSHVA LAACDAVLIA SGTATLEALL YKRPMVVAYR MAPLTFWVLK 300
RLVKSPYVSL PNLLAQRLLV PELLQDDATP EALARTLLPL IEDGHAQTEG 350
FDAIHRILRR DASNQAADAV LSLLGLPLSL 380
Length:380
Mass (Da):41,686
Last modified:June 1, 2003 - v1
Checksum:iD78706BD0A6E3FF0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016853 Genomic DNA. Translation: AAO55067.1.
RefSeqiNP_791372.1. NC_004578.1.

Genome annotation databases

EnsemblBacteriaiAAO55067; AAO55067; PSPTO_1547.
GeneIDi1183184.
KEGGipst:PSPTO_1547.
PATRICi19994346. VBIPseSyr93040_1573.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016853 Genomic DNA. Translation: AAO55067.1 .
RefSeqi NP_791372.1. NC_004578.1.

3D structure databases

ProteinModelPortali Q886N0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 223283.PSPTO_1547.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO55067 ; AAO55067 ; PSPTO_1547 .
GeneIDi 1183184.
KEGGi pst:PSPTO_1547.
PATRICi 19994346. VBIPseSyr93040_1573.

Phylogenomic databases

eggNOGi COG0763.
HOGENOMi HOG000018004.
KOi K00748.
OMAi VSPITYR.
OrthoDBi EOG6FBWZR.
PhylomeDBi Q886N0.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci PSYR223283:GJIX-1575-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DC3000.

Entry informationi

Entry nameiLPXB_PSESM
AccessioniPrimary (citable) accession number: Q886N0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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