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Q885J4

- ASTE_PSESM

UniProt

Q885J4 - ASTE_PSESM

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Protein

Succinylglutamate desuccinylase

Gene

astE

Organism
Pseudomonas syringae pv. tomato (strain DC3000)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Transforms N(2)-succinylglutamate into succinate and glutamate.UniRule annotation

Catalytic activityi

N-succinyl-L-glutamate + H2O = succinate + L-glutamate.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi59 – 591ZincUniRule annotation
Metal bindingi62 – 621ZincUniRule annotation
Metal bindingi151 – 1511ZincUniRule annotation
Active sitei215 – 2151UniRule annotation

GO - Molecular functioni

  1. hydrolase activity, acting on ester bonds Source: UniProtKB-HAMAP
  2. succinylglutamate desuccinylase activity Source: UniProtKB-EC
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine catabolic process to glutamate Source: UniProtKB-HAMAP
  2. arginine catabolic process to succinate Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Arginine metabolism

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciPSYR223283:GJIX-1873-MONOMER.
UniPathwayiUPA00185; UER00283.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinylglutamate desuccinylaseUniRule annotation (EC:3.5.1.96UniRule annotation)
Gene namesi
Name:astEUniRule annotation
Ordered Locus Names:PSPTO_1838
OrganismiPseudomonas syringae pv. tomato (strain DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002515: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 335335Succinylglutamate desuccinylasePRO_0000174645Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi223283.PSPTO_1838.

Structurei

3D structure databases

ProteinModelPortaliQ885J4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG2988.
HOGENOMiHOG000280300.
KOiK05526.
OMAiTAPIEIC.
OrthoDBiEOG613070.
PhylomeDBiQ885J4.

Family and domain databases

HAMAPiMF_00767. Arg_catab_AstE.
InterProiIPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view]
PfamiPF04952. AstE_AspA. 1 hit.
[Graphical view]
PIRSFiPIRSF017020. AstE. 1 hit.
TIGRFAMsiTIGR03242. arg_catab_astE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q885J4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLALGKLLEL TLAGREPAEK TQLTVEGVRM RWLAEGALEV RPPQARDNGT
60 70 80 90 100
DLLLSAGIHG NETAPIELLD ELIRSIARGD LKPRARILFL FGNPAAMRLG
110 120 130 140 150
ARYVEQDVNR LFNGRHEQSG GAEALRACEL ERLAASFFSL PDRYRLHYDL
160 170 180 190 200
HTAIRGSKIE QFALYPWKEG RQHSRFELAR LRAAGISAVL LQNKPSIVFS
210 220 230 240 250
AYTYEQLGAE AFTLELGKAR PFGQNRHVNL APLRLRLEQI IEGSEPQPDE
260 270 280 290 300
RLEGLQLFSV AREVIKRSDA FTFNLADDVE NFSELEKGYV LAEDVSDSRW
310 320 330
VVKEEGARII FPNPKVKNGL RAGIVIVPAD ADGLG
Length:335
Mass (Da):37,375
Last modified:June 1, 2003 - v1
Checksum:iE43CFD5829B97F3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA. Translation: AAO55357.1.
RefSeqiNP_791662.1. NC_004578.1.

Genome annotation databases

EnsemblBacteriaiAAO55357; AAO55357; PSPTO_1838.
GeneIDi1183479.
KEGGipst:PSPTO_1838.
PATRICi19994942. VBIPseSyr93040_1868.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA. Translation: AAO55357.1 .
RefSeqi NP_791662.1. NC_004578.1.

3D structure databases

ProteinModelPortali Q885J4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 223283.PSPTO_1838.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO55357 ; AAO55357 ; PSPTO_1838 .
GeneIDi 1183479.
KEGGi pst:PSPTO_1838.
PATRICi 19994942. VBIPseSyr93040_1868.

Phylogenomic databases

eggNOGi COG2988.
HOGENOMi HOG000280300.
KOi K05526.
OMAi TAPIEIC.
OrthoDBi EOG613070.
PhylomeDBi Q885J4.

Enzyme and pathway databases

UniPathwayi UPA00185 ; UER00283 .
BioCyci PSYR223283:GJIX-1873-MONOMER.

Family and domain databases

HAMAPi MF_00767. Arg_catab_AstE.
InterProi IPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view ]
Pfami PF04952. AstE_AspA. 1 hit.
[Graphical view ]
PIRSFi PIRSF017020. AstE. 1 hit.
TIGRFAMsi TIGR03242. arg_catab_astE. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DC3000.

Entry informationi

Entry nameiASTE_PSESM
AccessioniPrimary (citable) accession number: Q885J4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: June 1, 2003
Last modified: November 26, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3