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Protein

Replication enhancer

Gene

C3

Organism
Tomato leaf curl Bangalore virus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enhances infectivity and symptom expression.UniRule annotation
Increases viral DNA accumulation.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Host-virus interactionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Replication enhancerUniRule annotation
Short name:
REnUniRule annotation
Gene namesi
Name:C3Imported
OrganismiTomato leaf curl Bangalore virusImported
Taxonomic identifieri220608 [NCBI]
Taxonomic lineageiVirusesssDNA virusesGeminiviridaeBegomovirus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid proteinImported, Virion

Interactioni

Subunit structurei

Homooligomer. Interacts with the replication-associated protein (REP). Interacts with host proliferating cell nuclear antigen (PCNA). Interacts with host retinoblastoma-related protein 1 (RBR1), and may thereby deregulate the host cell cycle. Oligomerization and interaction with PCNA are necessary for optimal replication enhancement.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the geminiviridae replication enhancer protein family.UniRule annotation

Family and domain databases

InterProiIPR000657. Gemini_AL3.
[Graphical view]
PfamiPF01407. Gemini_AL3. 1 hit.
[Graphical view]
PRINTSiPR00231. GEMCOATAL3.
ProDomiPD001172. Gemini_AL3. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Q88559-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSRTGEPIT AAQTENGVFI WEIQNPLYFK ITEHHNRPFL SERDIITVQI
60 70 80 90 100
QFNHNLRKAL GIHKCFLAYR IWTTSQPLTG HFLRVFKSQV HIFLNNLGVI
110 120 130
SINNVNRAVD HVLWNVLHHV VYVEQSYSIK FNIY
Length:134
Mass (Da):15,772
Last modified:November 1, 1996 - v1
Checksum:i6F4762A2CE4271DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KP164857 Genomic DNA. Translation: AJW80849.1.
KP164858 Genomic DNA. Translation: AJW80855.1.
Z48182 Genomic DNA. Translation: CAA88231.1.
PIRiS59887.
RefSeqiNP_631953.1. NC_003891.1.

Genome annotation databases

GeneIDi944495.
KEGGivg:944495.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KP164857 Genomic DNA. Translation: AJW80849.1.
KP164858 Genomic DNA. Translation: AJW80855.1.
Z48182 Genomic DNA. Translation: CAA88231.1.
PIRiS59887.
RefSeqiNP_631953.1. NC_003891.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi944495.
KEGGivg:944495.

Family and domain databases

InterProiIPR000657. Gemini_AL3.
[Graphical view]
PfamiPF01407. Gemini_AL3. 1 hit.
[Graphical view]
PRINTSiPR00231. GEMCOATAL3.
ProDomiPD001172. Gemini_AL3. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

  1. "Nucleotide sequences from tomato leaf curl viruses from different countries: evidence for three geographically separate branches in evolution of the coat protein of whitefly-transmitted geminiviruses."
    Hong Y., Harrison B.D.
    J. Gen. Virol. 76:2043-2049(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Indian tomato leaf curl virusImported.
  2. "Molecular characterization of Tomato leaf curl Bangalore virus infecting tomato in India."
    Swarnalatha P., Venkatravanappa V., Jalali S., Krishna Reddy M.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: TC177Imported.
  3. "Molecular characterization of Tomato leaf curl Bangalore virus infecting tomato in India."
    Swarnalatha P., Jalali S., Venkatravanappa V., Krishna Reddy M.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: TC18Imported.

Entry informationi

Entry nameiQ88559_9GEMI
AccessioniPrimary (citable) accession number: Q88559
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.