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Q884Q3

- GCH12_PSESM

UniProt

Q884Q3 - GCH12_PSESM

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Protein
GTP cyclohydrolase 1 2
Gene
folE2, PSPTO_2035
Organism
Pseudomonas syringae pv. tomato (strain DC3000)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-KW
  2. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway
  2. one-carbon metabolic process Source: UniProtKB-HAMAP
  3. tetrahydrofolate biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

One-carbon metabolism

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPSYR223283:GJIX-2075-MONOMER.
UniPathwayiUPA00848; UER00151.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP cyclohydrolase 1 2 (EC:3.5.4.16)
Alternative name(s):
GTP cyclohydrolase I 2
Short name:
GTP-CH-I 2
Gene namesi
Name:folE2
Ordered Locus Names:PSPTO_2035
OrganismiPseudomonas syringae pv. tomato (strain DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002515: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 181181GTP cyclohydrolase 1 2UniRule annotation
PRO_0000119433Add
BLAST

Interactioni

Subunit structurei

Homopolymer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi223283.PSPTO_2035.

Structurei

3D structure databases

ProteinModelPortaliQ884Q3.
SMRiQ884Q3. Positions 14-181.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0302.
HOGENOMiHOG000221222.
KOiK01495.
OMAiKRTYDEE.
OrthoDBiEOG6XHC8G.
PhylomeDBiQ884Q3.

Family and domain databases

HAMAPiMF_00223. FolE.
InterProiIPR001474. GTP_CycHdrlase_I.
IPR018234. GTP_CycHdrlase_I_CS.
IPR020602. GTP_CycHdrlase_I_dom.
[Graphical view]
PANTHERiPTHR11109. PTHR11109. 1 hit.
PfamiPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00063. folE. 1 hit.
PROSITEiPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q884Q3-1 [UniParc]FASTAAdd to Basket

« Hide

MTLEQNYTAI LGQLGEDVSR EGLLDTPKRA AKAMQYLCRG YAQTLEEVTN    50
GALFSSDASE MVMVKDIELY SLCEHHLLPF IGKAHVAYIP NGKVLGLSKV 100
ARIVDMYARR LQIQENLSRQ IAEAIQQVTG AQGVAVVIEA KHMCMMMRGV 150
EKQNSAMITS VMLGEFRENA ATRSEFLSLI K 181
Length:181
Mass (Da):20,084
Last modified:June 1, 2003 - v1
Checksum:i4D07BABCC9C16743
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016853 Genomic DNA. Translation: AAO55553.1.
RefSeqiNP_791858.1. NC_004578.1.

Genome annotation databases

EnsemblBacteriaiAAO55553; AAO55553; PSPTO_2035.
GeneIDi1183680.
KEGGipst:PSPTO_2035.
PATRICi19995344. VBIPseSyr93040_2065.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016853 Genomic DNA. Translation: AAO55553.1 .
RefSeqi NP_791858.1. NC_004578.1.

3D structure databases

ProteinModelPortali Q884Q3.
SMRi Q884Q3. Positions 14-181.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 223283.PSPTO_2035.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO55553 ; AAO55553 ; PSPTO_2035 .
GeneIDi 1183680.
KEGGi pst:PSPTO_2035.
PATRICi 19995344. VBIPseSyr93040_2065.

Phylogenomic databases

eggNOGi COG0302.
HOGENOMi HOG000221222.
KOi K01495.
OMAi KRTYDEE.
OrthoDBi EOG6XHC8G.
PhylomeDBi Q884Q3.

Enzyme and pathway databases

UniPathwayi UPA00848 ; UER00151 .
BioCyci PSYR223283:GJIX-2075-MONOMER.

Family and domain databases

HAMAPi MF_00223. FolE.
InterProi IPR001474. GTP_CycHdrlase_I.
IPR018234. GTP_CycHdrlase_I_CS.
IPR020602. GTP_CycHdrlase_I_dom.
[Graphical view ]
PANTHERi PTHR11109. PTHR11109. 1 hit.
Pfami PF01227. GTP_cyclohydroI. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00063. folE. 1 hit.
PROSITEi PS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DC3000.

Entry informationi

Entry nameiGCH12_PSESM
AccessioniPrimary (citable) accession number: Q884Q3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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