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Q884Q3 (GCH12_PSESM) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 2

EC=3.5.4.16
Alternative name(s):
GTP cyclohydrolase I 2
Short name=GTP-CH-I 2
Gene names
Name:folE2
Ordered Locus Names:PSPTO_2035
OrganismPseudomonas syringae pv. tomato (strain DC3000) [Complete proteome] [HAMAP]
Taxonomic identifier223283 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length181 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP-Rule MF_00223

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP-Rule MF_00223

Subunit structure

Homopolymer By similarity. HAMAP-Rule MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 181181GTP cyclohydrolase 1 2 HAMAP-Rule MF_00223
PRO_0000119433

Sequences

Sequence LengthMass (Da)Tools
Q884Q3 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 4D07BABCC9C16743

FASTA18120,084
        10         20         30         40         50         60 
MTLEQNYTAI LGQLGEDVSR EGLLDTPKRA AKAMQYLCRG YAQTLEEVTN GALFSSDASE 

        70         80         90        100        110        120 
MVMVKDIELY SLCEHHLLPF IGKAHVAYIP NGKVLGLSKV ARIVDMYARR LQIQENLSRQ 

       130        140        150        160        170        180 
IAEAIQQVTG AQGVAVVIEA KHMCMMMRGV EKQNSAMITS VMLGEFRENA ATRSEFLSLI 


K 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016853 Genomic DNA. Translation: AAO55553.1.
RefSeqNP_791858.1. NC_004578.1.

3D structure databases

ProteinModelPortalQ884Q3.
SMRQ884Q3. Positions 14-181.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING223283.PSPTO_2035.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO55553; AAO55553; PSPTO_2035.
GeneID1183680.
KEGGpst:PSPTO_2035.
PATRIC19995344. VBIPseSyr93040_2065.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
HOGENOMHOG000221222.
KOK01495.
OMAKRTYDEE.
OrthoDBEOG6XHC8G.
PhylomeDBQ884Q3.

Enzyme and pathway databases

BioCycPSYR223283:GJIX-2075-MONOMER.
UniPathwayUPA00848; UER00151.

Family and domain databases

HAMAPMF_00223. FolE.
InterProIPR001474. GTP_CycHdrlase_I.
IPR018234. GTP_CycHdrlase_I_CS.
IPR020602. GTP_CycHdrlase_I_dom.
[Graphical view]
PANTHERPTHR11109. PTHR11109. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. folE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGCH12_PSESM
AccessionPrimary (citable) accession number: Q884Q3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways