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Q884Q3

- GCH12_PSESM

UniProt

Q884Q3 - GCH12_PSESM

Protein

GTP cyclohydrolase 1 2

Gene

folE2

Organism
Pseudomonas syringae pv. tomato (strain DC3000)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. GTP binding Source: UniProtKB-KW
    2. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP
    3. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway
    2. one-carbon metabolic process Source: UniProtKB-HAMAP
    3. tetrahydrofolate biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    One-carbon metabolism

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciPSYR223283:GJIX-2075-MONOMER.
    UniPathwayiUPA00848; UER00151.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTP cyclohydrolase 1 2UniRule annotation (EC:3.5.4.16UniRule annotation)
    Alternative name(s):
    GTP cyclohydrolase I 2UniRule annotation
    Short name:
    GTP-CH-I 2UniRule annotation
    Gene namesi
    Name:folE2UniRule annotation
    Ordered Locus Names:PSPTO_2035
    OrganismiPseudomonas syringae pv. tomato (strain DC3000)
    Taxonomic identifieri223283 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002515: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 181181GTP cyclohydrolase 1 2PRO_0000119433Add
    BLAST

    Interactioni

    Subunit structurei

    Homopolymer.UniRule annotation

    Protein-protein interaction databases

    STRINGi223283.PSPTO_2035.

    Structurei

    3D structure databases

    ProteinModelPortaliQ884Q3.
    SMRiQ884Q3. Positions 14-181.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP cyclohydrolase I family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0302.
    HOGENOMiHOG000221222.
    KOiK01495.
    OMAiKRTYDEE.
    OrthoDBiEOG6XHC8G.
    PhylomeDBiQ884Q3.

    Family and domain databases

    HAMAPiMF_00223. FolE.
    InterProiIPR001474. GTP_CycHdrlase_I.
    IPR018234. GTP_CycHdrlase_I_CS.
    IPR020602. GTP_CycHdrlase_I_dom.
    [Graphical view]
    PANTHERiPTHR11109. PTHR11109. 1 hit.
    PfamiPF01227. GTP_cyclohydroI. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00063. folE. 1 hit.
    PROSITEiPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
    PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q884Q3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTLEQNYTAI LGQLGEDVSR EGLLDTPKRA AKAMQYLCRG YAQTLEEVTN    50
    GALFSSDASE MVMVKDIELY SLCEHHLLPF IGKAHVAYIP NGKVLGLSKV 100
    ARIVDMYARR LQIQENLSRQ IAEAIQQVTG AQGVAVVIEA KHMCMMMRGV 150
    EKQNSAMITS VMLGEFRENA ATRSEFLSLI K 181
    Length:181
    Mass (Da):20,084
    Last modified:June 1, 2003 - v1
    Checksum:i4D07BABCC9C16743
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016853 Genomic DNA. Translation: AAO55553.1.
    RefSeqiNP_791858.1. NC_004578.1.

    Genome annotation databases

    EnsemblBacteriaiAAO55553; AAO55553; PSPTO_2035.
    GeneIDi1183680.
    KEGGipst:PSPTO_2035.
    PATRICi19995344. VBIPseSyr93040_2065.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016853 Genomic DNA. Translation: AAO55553.1 .
    RefSeqi NP_791858.1. NC_004578.1.

    3D structure databases

    ProteinModelPortali Q884Q3.
    SMRi Q884Q3. Positions 14-181.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 223283.PSPTO_2035.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO55553 ; AAO55553 ; PSPTO_2035 .
    GeneIDi 1183680.
    KEGGi pst:PSPTO_2035.
    PATRICi 19995344. VBIPseSyr93040_2065.

    Phylogenomic databases

    eggNOGi COG0302.
    HOGENOMi HOG000221222.
    KOi K01495.
    OMAi KRTYDEE.
    OrthoDBi EOG6XHC8G.
    PhylomeDBi Q884Q3.

    Enzyme and pathway databases

    UniPathwayi UPA00848 ; UER00151 .
    BioCyci PSYR223283:GJIX-2075-MONOMER.

    Family and domain databases

    HAMAPi MF_00223. FolE.
    InterProi IPR001474. GTP_CycHdrlase_I.
    IPR018234. GTP_CycHdrlase_I_CS.
    IPR020602. GTP_CycHdrlase_I_dom.
    [Graphical view ]
    PANTHERi PTHR11109. PTHR11109. 1 hit.
    Pfami PF01227. GTP_cyclohydroI. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00063. folE. 1 hit.
    PROSITEi PS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
    PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DC3000.

    Entry informationi

    Entry nameiGCH12_PSESM
    AccessioniPrimary (citable) accession number: Q884Q3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 16, 2004
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3