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Q87WW4

- SYW_PSESM

UniProt

Q87WW4 - SYW_PSESM

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Protein
Tryptophan--tRNA ligase
Gene
trpS, PSPTO_4429
Organism
Pseudomonas syringae pv. tomato (strain DC3000)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei207 – 2071ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. tryptophan-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tryptophanyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPSYR223283:GJIX-4495-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Tryptophan--tRNA ligase (EC:6.1.1.2)
Alternative name(s):
Tryptophanyl-tRNA synthetase
Short name:
TrpRS
Gene namesi
Name:trpS
Ordered Locus Names:PSPTO_4429
OrganismiPseudomonas syringae pv. tomato (strain DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002515: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 449449Tryptophan--tRNA ligaseUniRule annotation
PRO_0000136664Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi223283.PSPTO_4429.

Structurei

3D structure databases

ProteinModelPortaliQ87WW4.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi11 – 199"HIGH" regionUniRule annotation
Motifi204 – 2085"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0180.
HOGENOMiHOG000059939.
KOiK01867.
OMAiLELYWIL.
OrthoDBiEOG686NJQ.
PhylomeDBiQ87WW4.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00140_B. Trp_tRNA_synth_B.
InterProiIPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view]
PANTHERiPTHR10055. PTHR10055. 1 hit.
PfamiPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSiPR01039. TRNASYNTHTRP.
TIGRFAMsiTIGR00233. trpS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q87WW4-1 [UniParc]FASTAAdd to Basket

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MTTRILTGIT TTGTPHLGNY AGAIRPAIVA SRQSDVDSFY FLADYHALIK    50
CDDPLRIQRS RLEIAATWLA AGLDVDRVTF YRQSDIPEIP ELTWLLTCVA 100
AKGLLNRAHA YKASVDKNVE SCEDPDAGIT MGLYSYPVLM AADILMFNAH 150
QVPVGRDQIQ HVEMARDIGQ RFNHLFGKGR EFFVMPEALI EESVATLPGL 200
DGRKMSKSYD NTIPLFSSAK DMKSAISRIV TDSLAPGEAK DPDNSHLFTL 250
YQAFSTPEQC AQFRSELLQG LGWGEAKTRM FTLLDEQLGE AREQYLSLIE 300
RPADLEDILL AGAQKARRVA TPFLEELREA VGLRSFRTAV QNADTGKKKT 350
TKGARFVSFR EDDGSFRFRL LAADGEQLLL SRTFADGKAA GIVSKQLQQG 400
GELDLRSEAD RFTLWLNGEC VADSPVFADA TARDNAVETL KLALAPQQD 449
Length:449
Mass (Da):49,635
Last modified:June 1, 2003 - v1
Checksum:i7697DB7C99120F85
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016853 Genomic DNA. Translation: AAO57878.1.
RefSeqiNP_794183.1. NC_004578.1.

Genome annotation databases

EnsemblBacteriaiAAO57878; AAO57878; PSPTO_4429.
GeneIDi1186110.
KEGGipst:PSPTO_4429.
PATRICi20000368. VBIPseSyr93040_4544.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016853 Genomic DNA. Translation: AAO57878.1 .
RefSeqi NP_794183.1. NC_004578.1.

3D structure databases

ProteinModelPortali Q87WW4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 223283.PSPTO_4429.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO57878 ; AAO57878 ; PSPTO_4429 .
GeneIDi 1186110.
KEGGi pst:PSPTO_4429.
PATRICi 20000368. VBIPseSyr93040_4544.

Phylogenomic databases

eggNOGi COG0180.
HOGENOMi HOG000059939.
KOi K01867.
OMAi LELYWIL.
OrthoDBi EOG686NJQ.
PhylomeDBi Q87WW4.

Enzyme and pathway databases

BioCyci PSYR223283:GJIX-4495-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
HAMAPi MF_00140_B. Trp_tRNA_synth_B.
InterProi IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view ]
PANTHERi PTHR10055. PTHR10055. 1 hit.
Pfami PF00579. tRNA-synt_1b. 1 hit.
[Graphical view ]
PRINTSi PR01039. TRNASYNTHTRP.
TIGRFAMsi TIGR00233. trpS. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DC3000.

Entry informationi

Entry nameiSYW_PSESM
AccessioniPrimary (citable) accession number: Q87WW4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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