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Protein

ATP synthase subunit alpha

Gene

atpA

Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.UniRule annotation

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei374Required for activityUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi170 – 177ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processATP synthesis, Hydrogen ion transport, Ion transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPSYR223283:G1G0D-5678-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alphaUniRule annotation (EC:3.6.3.14UniRule annotation)
Alternative name(s):
ATP synthase F1 sector subunit alphaUniRule annotation
F-ATPase subunit alphaUniRule annotation
Gene namesi
Name:atpAUniRule annotation
Ordered Locus Names:PSPTO_5601
OrganismiPseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Taxonomic identifieri223283 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002515 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, CF(1), Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002383331 – 514ATP synthase subunit alphaAdd BLAST514

2D gel databases

World-2DPAGEi0008:Q87TT2

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.UniRule annotation

Protein-protein interaction databases

STRINGi223283.PSPTO_5601

Structurei

3D structure databases

ProteinModelPortaliQ87TT2
SMRiQ87TT2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDG Bacteria
COG0056 LUCA
HOGENOMiHOG000130111
KOiK02111
OMAiGNAQIKS
OrthoDBiPOG091H01QH
PhylomeDBiQ87TT2

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
PIRSFiPIRSF039088 F_ATPase_subunit_alpha, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

Q87TT2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQLNPSEIS EIIKGRIDKL DVTSQARNEG TVVSVSDGIV RIHGLADVMY
60 70 80 90 100
GEMIEFPGGV YGMALNLEQD SVGAVVLGAY TTLAEGMSAK CTGRILEVPV
110 120 130 140 150
GKELLGRVVD ALGNPVDGKG PLNNTETDAV EKVAPGVIWR KSVDQPVQTG
160 170 180 190 200
YKAVDAMIPV GRGQRELIIG DRQIGKTALA IDAIINQKNS GIFCVYVAIG
210 220 230 240 250
QKQSTIANVV RKLEENGALA NTIVVAASAS ESAALQFLAP YSGCTMGEFF
260 270 280 290 300
RDRGEDALIV YDDLSKQAVA YRQISLLLRR PPGREAYPGD VFYLHSRLLE
310 320 330 340 350
RASRVSEEYV EKFTNGAVTG KTGSLTALPI IETQAGDVSA FVPTNVISIT
360 370 380 390 400
DGQIFLESAM FNSGIRPAVN AGVSVSRVGG AAQTKIIKKL SGGIRTALAQ
410 420 430 440 450
YRELAAFAQF ASDLDEATRK QLEHGQRVTE LMKQKQYAPM SIADMALSLY
460 470 480 490 500
AAERGFLTDV EIAKIGSFEQ ALIAYFNRDH ADLMAKINVK GDFNDEIDAG
510
MKAGIEKFKA TQTW
Length:514
Mass (Da):55,324
Last modified:June 1, 2003 - v1
Checksum:i27ABFFBB60FEF48E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016853 Genomic DNA Translation: AAO59014.1
RefSeqiNP_795319.1, NC_004578.1
WP_003377895.1, NC_004578.1

Genome annotation databases

EnsemblBacteriaiAAO59014; AAO59014; PSPTO_5601
GeneIDi1187293
KEGGipst:PSPTO_5601
PATRICifig|223283.9.peg.5738

Similar proteinsi

Entry informationi

Entry nameiATPA_PSESM
AccessioniPrimary (citable) accession number: Q87TT2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: June 1, 2003
Last modified: March 28, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health