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Protein

Glutamate-ammonia-ligase adenylyltransferase

Gene

glnE

Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Adenylation and deadenylation of glutamate--ammonia ligase.UniRule annotation

Catalytic activityi

ATP + [L-glutamate:ammonia ligase (ADP-forming)]-L-tyrosine = diphosphate + [L-glutamate:ammonia ligase (ADP-forming)]-O(4)-(5'-adenylyl)-L-tyrosine.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Magnesium, Nucleotide-binding

Enzyme and pathway databases

BioCyciVPAR223926:GHK4-435-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-ammonia-ligase adenylyltransferaseUniRule annotation (EC:2.7.7.42UniRule annotation)
Alternative name(s):
Glutamine-synthetase adenylyltransferase
Short name:
ATaseUniRule annotation
[Glutamate--ammonia-ligase] adenylyltransferaseUniRule annotation
Gene namesi
Name:glnEUniRule annotation
Ordered Locus Names:VP0423
OrganismiVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Taxonomic identifieri223926 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002493 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 947947Glutamate-ammonia-ligase adenylyltransferasePRO_0000209282Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi223926.VP0423.

Structurei

3D structure databases

ProteinModelPortaliQ87SK0.
SMRiQ87SK0. Positions 1-440.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni94 – 305212GlnE 1Add
BLAST
Regioni612 – 833222GlnE 2Add
BLAST

Sequence similaritiesi

Belongs to the GlnE family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105CE6. Bacteria.
COG1391. LUCA.
HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q87SK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLPSSLVSV AESAVQNAQE AGYLQSWPNE VVEQFHYVSA LSQFITETIH
60 70 80 90 100
RDEALAQQLP TMLSELSRHQ AYRTRLAALL AECPDEMSGH RVLRQFRNRE
110 120 130 140 150
MVYIAWKDFL HAWTLEESLR HLSQLAEAMI FETYQWQYKI CCAEWGTPTN
160 170 180 190 200
AEGEAQPMLI IGMGKLGGGE LNFSSDIDLI FTYPENGETQ GARRSIANAQ
210 220 230 240 250
FFTRLGQRII KALDQQTFDG FCYRVDMRLR PFGESGPLVM SYAALEDYYQ
260 270 280 290 300
EQGRDWERYA MIKARVMGCE MYPQYQELRK MLRPFVFRRY IDFSAIQSLR
310 320 330 340 350
RMKSMISSEV RRRGLTNNIK LGAGGIREIE FIAQVFQLIR GGREPSLRNR
360 370 380 390 400
GLLETLSGIE ELALLTPQEV SNLEAAYKYL RQLENLLQAM ADKQTQTLPD
410 420 430 440 450
CDIERLKLAT AMQLESWDLL IEQTQQHMNK VHQVFETLIG DDEEDEGSTI
460 470 480 490 500
ARHFHELWDM ANKQDVLELI LEQDIQVEEP AIFSKAIINF KADLAKKTLG
510 520 530 540 550
PRGREVLNRL MPKVFDAVFA HPDAQFGLPR VLHLLHNICT RTTYLELLDE
560 570 580 590 600
HPAALVQLVR LCTASPMISE QLSRYPILLD ELIDPQQLYN PIPLDSYRTE
610 620 630 640 650
LRDFLARIPE DDMEQQMEAL RQFKQICILR IAAADIAGVL PVMKVSDHLT
660 670 680 690 700
YLAEAIVEAV VSQAWLQVSE KYGEPTHVKD REGKGFAVIG YGKVGGWELG
710 720 730 740 750
YNSDLDIVFM HDCPVNVYTD GKKEIDGRQF YLRLAQRIIH IFSTRTASGI
760 770 780 790 800
LYEVDTRLRP SGASGLLVSP TDAFDDYQHQ DAWTWEHQAL VRARMIYGDE
810 820 830 840 850
PLAIAFHNTR HDVLCKPRDE QTLKKEVVEM REKMRDHLGG KKSGRFMIKQ
860 870 880 890 900
DVGGITDIEF LAQYLVLNYS HEKPKLTRWC DNVRIYETLI AQGVMEEDQA
910 920 930 940
MQLIRAYTAM RNEIHHRNLL NLDADVVEDK FVAEREWVKQ AWNQWFA
Length:947
Mass (Da):109,195
Last modified:June 1, 2003 - v1
Checksum:i4854E2D668AC5DE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA. Translation: BAC58686.1.
RefSeqiNP_796802.1. NC_004603.1.
WP_005455447.1. NC_004603.1.

Genome annotation databases

EnsemblBacteriaiBAC58686; BAC58686; BAC58686.
GeneIDi1187891.
KEGGivpa:VP0423.
PATRICi20139056. VBIVibPar50997_0402.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA. Translation: BAC58686.1.
RefSeqiNP_796802.1. NC_004603.1.
WP_005455447.1. NC_004603.1.

3D structure databases

ProteinModelPortaliQ87SK0.
SMRiQ87SK0. Positions 1-440.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi223926.VP0423.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC58686; BAC58686; BAC58686.
GeneIDi1187891.
KEGGivpa:VP0423.
PATRICi20139056. VBIVibPar50997_0402.

Phylogenomic databases

eggNOGiENOG4105CE6. Bacteria.
COG1391. LUCA.
HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.

Enzyme and pathway databases

BioCyciVPAR223926:GHK4-435-MONOMER.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLNE_VIBPA
AccessioniPrimary (citable) accession number: Q87SK0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.