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Q87S65 (RLUD_VIBPA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal large subunit pseudouridine synthase D

EC=5.4.99.23
Alternative name(s):
23S rRNA pseudouridine(1911/1915/1917) synthase
rRNA pseudouridylate synthase D
rRNA-uridine isomerase D
Gene names
Name:rluD
Ordered Locus Names:VP0559
OrganismVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) [Complete proteome] [HAMAP]
Taxonomic identifier223926 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length325 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA By similarity.

Catalytic activity

23S rRNA uridine(1911)/uridine(1915)/uridine(1917) = 23S rRNA pseudouridine(1911)/pseudouridine(1915)/pseudouridine(1917).

Sequence similarities

Belongs to the pseudouridine synthase RluA family.

Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
   Biological processrRNA processing
   LigandRNA-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpseudouridine synthesis

Inferred from electronic annotation. Source: InterPro

rRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

pseudouridine synthase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 325325Ribosomal large subunit pseudouridine synthase D
PRO_0000162703

Regions

Domain18 – 9174S4 RNA-binding

Sites

Active site1391 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q87S65 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: D3359215265F1156

FASTA32536,604
        10         20         30         40         50         60 
MAQQIVLTNT VKDSQLGQRL DQAIAELFAD FSRSRLKEWL LDGKVQVNGE VVTKPRTKVM 

        70         80         90        100        110        120 
GGEEITLQAE LEDEERWEAQ DIPLDIVYED DDIIVINKPR DFVVHPGAGT PDGTVLNALL 

       130        140        150        160        170        180 
HHYPDIAEVP RAGIVHRLDK DTTGLMVVAK TVPAQTRLVR ALQKRNITRE YEAIAIGRMT 

       190        200        210        220        230        240 
AGGKVDQPIG RHSTKRTLMA VAPLGKPAVT HYRVAEHFRE HTRIRLRLET GRTHQIRVHM 

       250        260        270        280        290        300 
SYLQHPLLGD TAYGGRARIP TGASQELTDM IRGFDRQALH AVMLRFEHPI TGEELEFHAP 

       310        320 
VPDDMVAMTE ALRKDTEEYG LPDEF 

« Hide

References

[1]"Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae."
Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K., Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S., Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.
Lancet 361:743-749(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RIMD 2210633.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000031 Genomic DNA. Translation: BAC58822.1.
RefSeqNP_796938.1. NC_004603.1.

3D structure databases

ProteinModelPortalQ87S65.
SMRQ87S65. Positions 2-319.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING223926.VP0559.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC58822; BAC58822; BAC58822.
GeneID1188027.
KEGGvpa:VP0559.
PATRIC20139314. VBIVibPar50997_0531.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0564.
HOGENOMHOG000275919.
KOK06180.
OMANALLHHV.
OrthoDBEOG6P070X.
ProtClustDBPRK11180.

Enzyme and pathway databases

BioCycVPAR223926:GHK4-571-MONOMER.

Family and domain databases

Gene3D3.10.290.10. 1 hit.
InterProIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTSM00363. S4. 1 hit.
[Graphical view]
SUPFAMSSF55120. SSF55120. 1 hit.
TIGRFAMsTIGR00005. rluA_subfam. 1 hit.
PROSITEPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRLUD_VIBPA
AccessionPrimary (citable) accession number: Q87S65
Entry history
Integrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: June 1, 2003
Last modified: November 13, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families