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Protein

Methionine import ATP-binding protein MetN

Gene

metN

Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi38 – 45ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
Biological processAmino-acid transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciVPAR223926:G1GTB-725-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Methionine import ATP-binding protein MetNUniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
Name:metNUniRule annotation
Ordered Locus Names:VP0706
OrganismiVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Taxonomic identifieri223926 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002493 Componenti: Chromosome 1

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002704351 – 344Methionine import ATP-binding protein MetNAdd BLAST344

Proteomic databases

PRIDEiQ87RS1

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).UniRule annotation

Protein-protein interaction databases

STRINGi223926.VP0706

Structurei

Secondary structure

1344
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi251 – 256Combined sources6
Beta strandi257 – 260Combined sources4
Beta strandi266 – 273Combined sources8
Helixi282 – 289Combined sources8
Beta strandi293 – 304Combined sources12
Beta strandi307 – 318Combined sources12
Helixi320 – 332Combined sources13
Beta strandi336 – 343Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2QRRX-ray1.71A/B247-344[»]
ProteinModelPortaliQ87RS1
SMRiQ87RS1
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ87RS1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 241ABC transporterUniRule annotationAdd BLAST240

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. [View classification]UniRule annotation

Phylogenomic databases

eggNOGiENOG4108JEI Bacteria
COG1135 LUCA
KOiK02071
OMAiLIRLINC

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR026253 ABC_MetN
IPR012692 ABC_MetN_proteobac
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR017908 ABC_transprt_methionine_MetN_C
IPR018449 NIL_domain
IPR027417 P-loop_NTPase
PANTHERiPTHR43166:SF5 PTHR43166:SF5, 1 hit
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
PF09383 NIL, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00930 NIL, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR02314 ABC_MetN, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
PS51264 METN, 1 hit

Sequencei

Sequence statusi: Complete.

Q87RS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEIKNVNKV FYQGSKEILA LKDINLHIAK GTIFGVIGSS GAGKSTLIRC
60 70 80 90 100
VNMLEAPSSG SIIVDGVDLT TLSKKQLVET RRNIGMIFQH FNLLSSRTVF
110 120 130 140 150
DNVALPLELA GKDKSQITTK VTELLKLVGL ADKHESYPSN LSGGQKQRVA
160 170 180 190 200
IARALASDPS VLLCDEATSA LDPATTQSIL ELLKEINRKL NITILLITHE
210 220 230 240 250
MEVVKSICHE VAIIGGGELV EKGTVGDIFA HPKTELAHEF IRSTLDLSIP
260 270 280 290 300
EDYQARLQPN RVEGSYPLVR MEFTGATVDA PLMSQISRKY NIDVSILSSD
310 320 330 340
LDYAGGVKFG MMVAELFGNE QDDSAAIEYL REHNVKVEVL GYVL
Length:344
Mass (Da):37,567
Last modified:June 1, 2003 - v1
Checksum:i315DB9DF298B40D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA Translation: BAC58969.1
RefSeqiNP_797085.1, NC_004603.1
WP_005459161.1, NC_004603.1

Genome annotation databases

EnsemblBacteriaiBAC58969; BAC58969; BAC58969
GeneIDi1188181
KEGGivpa:VP0706
PATRICifig|223926.6.peg.675

Similar proteinsi

Entry informationi

Entry nameiMETN_VIBPA
AccessioniPrimary (citable) accession number: Q87RS1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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