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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei67L-glutamineUniRule annotation1
Binding sitei212L-glutamineUniRule annotation1
Binding sitei231ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi35 – 37ATPUniRule annotation3
Nucleotide bindingi41 – 47ATPUniRule annotation7
Nucleotide bindingi261 – 262ATPUniRule annotation2
Nucleotide bindingi269 – 271ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:VP0832
OrganismiVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Taxonomic identifieri223926 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002493 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001958531 – 556Glutamine--tRNA ligaseAdd BLAST556

Proteomic databases

PRIDEiQ87RG4.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi223926.VP0832.

Structurei

3D structure databases

ProteinModelPortaliQ87RG4.
SMRiQ87RG4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi34 – 44"HIGH" regionUniRule annotationAdd BLAST11
Motifi268 – 272"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 3 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q87RG4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEADARPSN FIRQIIDKDL ADGKHTSVHT RFPPEPNGYL HIGHAKSICL
60 70 80 90 100
NFGIAQDYQG QCNLRFDDTN PEKEDIEYVE SIKKDVNWLG FEWDGEVCYS
110 120 130 140 150
SNYFDKLYEY AIELINKGLA YVDELSPEQI REYRGTLKEP GKPSPYRDRS
160 170 180 190 200
VEENLALFEK MRAGEFEEGK ACLRAKIDMG SSFMVMRDPV LYRVRFATHH
210 220 230 240 250
QTGDKWCIYP MYDFTHCISD ALEGITHSIC TLEFMDNRRL YDWVLDNITI
260 270 280 290 300
DCRPHQYEFS RLNLEYTVMS KRKLNQLVTE KLVNGWDDPR MPTVSGLRRR
310 320 330 340 350
GFTPASIREF CKRIGVTKQE NMIEFSSLES CIRDDLNENA PRAMAVLDPV
360 370 380 390 400
KVVIENFEVG AVENLTLANH PNKPEMGERE VPFTREVWIE REDFREEANK
410 420 430 440 450
KYKRLVLGKE VRLRGAYVIK AERVEKDAEG NITTIYCTYD PETLGKNPAD
460 470 480 490 500
GRKVKGVIHW VSADKALPAE IRLYDRLFTV PNPAAAEDFA STINTDSLVV
510 520 530 540 550
INGFVEPSLA SAEAEQGYQF ERMGYFCADS KDSTADNLVF NRTVGLRDTW

AKIENQ
Length:556
Mass (Da):63,969
Last modified:May 23, 2003 - v1
Checksum:i355B526332146B44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA. Translation: BAC59095.1.
RefSeqiNP_797211.1. NC_004603.1.
WP_005454579.1. NC_004603.1.

Genome annotation databases

EnsemblBacteriaiBAC59095; BAC59095; BAC59095.
GeneIDi1188329.
KEGGivpa:VP0832.
PATRICifig|223926.6.peg.788.

Similar proteinsi

Entry informationi

Entry nameiSYQ_VIBPA
AccessioniPrimary (citable) accession number: Q87RG4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: May 23, 2003
Last modified: August 30, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families