Q87QI7 (TORA_VIBPA) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 69.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Trimethylamine-N-oxide reductase Short name=TMAO reductase Short name=Trimethylamine oxidase EC=1.7.2.3 | ||||
| Gene names |
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| Organism | Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 223926 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio › ![]() |
Protein attributes
| Sequence length | 820 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions By similarity. |
| Catalytic activity | Trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+. |
| Cofactor | Molybdenum (molybdopterin) By similarity. |
| Subcellular location | Periplasm By similarity. |
| Post-translational modification | Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. |
| Sequence similarities | Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Periplasm |
| Domain | Signal |
| Ligand | Molybdenum |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Cellular_component | periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | electron carrier activity Inferred from electronic annotation. Source: InterPro molybdenum ion bindingInferred from electronic annotation. Source: InterPro trimethylamine-N-oxide reductase (cytochrome c) activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae." Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K., Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S., Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T. Lancet 361:743-749(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RIMD 2210633. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000031 Genomic DNA. Translation: BAC59425.1. |
| RefSeq | NP_797541.1. NC_004603.1. |
3D structure databases | |
| ProteinModelPortal | Q87QI7. |
| SMR | Q87QI7. Positions 40-819. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 223926.VP1162. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | BAC59425; BAC59425; BAC59425. |
| GeneID | 1188667. |
| KEGG | vpa:VP1162. |
| PATRIC | 20140532. VBIVibPar50997_1103. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0243. |
| HOGENOM | HOG000284391. |
| KO | K07811. |
| OMA | HASFRED. |
| ProtClustDB | PRK15102. |
Family and domain databases | |
| Gene3D | 2.40.40.20. 1 hit. |
| InterPro | IPR009010. Asp_de-COase-like_dom. IPR006657. MoPterin_dinucl-bd_dom. IPR006656. Mopterin_OxRdtase. IPR006655. Mopterin_OxRdtase_prok_CS. IPR006311. TAT_signal. IPR019546. TAT_signal_bac_arc. [Graphical view] |
| Pfam | PF00384. Molybdopterin. 1 hit. PF01568. Molydop_binding. 1 hit. [Graphical view] |
| SUPFAM | SSF50692. Asp_decarb_fold. 1 hit. |
| TIGRFAMs | TIGR01409. TAT_signal_seq. 1 hit. |
| PROSITE | PS00551. MOLYBDOPTERIN_PROK_1. False negative. PS00490. MOLYBDOPTERIN_PROK_2. 1 hit. PS00932. MOLYBDOPTERIN_PROK_3. 1 hit. PS51318. TAT. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | TORA_VIBPA | ||||||||
| Accession | Primary (citable) accession number: Q87QI7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with
