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Q87NB7

- RLUB_VIBPA

UniProt

Q87NB7 - RLUB_VIBPA

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Protein

Ribosomal large subunit pseudouridine synthase B

Gene
rluB, VP1951
Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA By similarity.

Catalytic activityi

23S rRNA uridine(2605) = 23S rRNA pseudouridine(2605).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei109 – 1091Nucleophile By similarity

GO - Molecular functioni

  1. pseudouridine synthase activity Source: InterPro
  2. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
  2. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciVPAR223926:GHK4-2006-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal large subunit pseudouridine synthase B (EC:5.4.99.22)
Alternative name(s):
23S rRNA pseudouridine(2605) synthase
rRNA pseudouridylate synthase B
rRNA-uridine isomerase B
Gene namesi
Name:rluB
Ordered Locus Names:VP1951
OrganismiVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Taxonomic identifieri223926 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000002493: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 312312Ribosomal large subunit pseudouridine synthase BPRO_0000099993Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi223926.VP1951.

Structurei

3D structure databases

ProteinModelPortaliQ87NB7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 7472S4 RNA-bindingAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1187.
HOGENOMiHOG000044954.
KOiK06178.
OMAiARSQKIR.
OrthoDBiEOG6130DV.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
IPR018496. PsdUridine_synth_RsuA/RluB_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00093. TIGR00093. 1 hit.
PROSITEiPS01149. PSI_RSU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q87NB7-1 [UniParc]FASTAAdd to Basket

« Hide

MSEKLQKVLA RAGHGSRREI ESLIKSGRVS VNGVVAKLGE RLEDESSVVR    50
IDGHIVSAKV QEEVICRVLA YYKPEGELCT RHDPEGRRTV FDRLPKIRGS 100
RWISVGRLDA NTSGLLLFTT DGELANRLMH PSRQVEREYL VRVFGEVTEQ 150
KVRNLVKGVE LEDGLARFED VVYAGGEGMN HTFYVVINEG RNREVRRLWE 200
SQECTVSRLK RVRYGDIFLD KKLPRGGWME LDLKEVNYLR ELVELRPEKE 250
TMLDLSKDNT SRKRERARSQ KIRRAVKRHE ERVSTSKGRS NNPARRKPKK 300
NAGEQGARNK HR 312
Length:312
Mass (Da):35,996
Last modified:June 1, 2003 - v1
Checksum:i6440A74C58CC2893
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000031 Genomic DNA. Translation: BAC60214.1.
RefSeqiNP_798330.1. NC_004603.1.

Genome annotation databases

EnsemblBacteriaiBAC60214; BAC60214; BAC60214.
GeneIDi1189462.
KEGGivpa:VP1951.
PATRICi20142070. VBIVibPar50997_1866.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000031 Genomic DNA. Translation: BAC60214.1 .
RefSeqi NP_798330.1. NC_004603.1.

3D structure databases

ProteinModelPortali Q87NB7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 223926.VP1951.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC60214 ; BAC60214 ; BAC60214 .
GeneIDi 1189462.
KEGGi vpa:VP1951.
PATRICi 20142070. VBIVibPar50997_1866.

Phylogenomic databases

eggNOGi COG1187.
HOGENOMi HOG000044954.
KOi K06178.
OMAi ARSQKIR.
OrthoDBi EOG6130DV.

Enzyme and pathway databases

BioCyci VPAR223926:GHK4-2006-MONOMER.

Family and domain databases

Gene3Di 3.10.290.10. 1 hit.
InterProi IPR020103. PsdUridine_synth_cat_dom.
IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
IPR018496. PsdUridine_synth_RsuA/RluB_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view ]
Pfami PF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view ]
SMARTi SM00363. S4. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
TIGRFAMsi TIGR00093. TIGR00093. 1 hit.
PROSITEi PS01149. PSI_RSU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae."
    Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K., Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S., Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.
    Lancet 361:743-749(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RIMD 2210633.

Entry informationi

Entry nameiRLUB_VIBPA
AccessioniPrimary (citable) accession number: Q87NB7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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