ID   LUXU_VIBPA              Reviewed;         112 AA.
AC   Q87MX8;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   RecName: Full=Phosphorelay protein LuxU;
GN   Name=luxU; OrderedLocusNames=VP2098;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
CC   -!- FUNCTION: Phosphorelay protein which receives a sensory signal from a
CC       sensor kinase and transmit it to LuxO. At low cell density, a
CC       phosphoryl group is transferred from the sensor kinase, probably on
CC       His-56 and this phosphoryl group is further transferred to LuxO.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
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DR   EMBL; BA000031; BAC60361.1; -; Genomic_DNA.
DR   RefSeq; NP_798477.1; NC_004603.1.
DR   RefSeq; WP_005482417.1; NC_004603.1.
DR   AlphaFoldDB; Q87MX8; -.
DR   SMR; Q87MX8; -.
DR   GeneID; 1189609; -.
DR   KEGG; vpa:VP2098; -.
DR   PATRIC; fig|223926.6.peg.2009; -.
DR   eggNOG; COG2198; Bacteria.
DR   HOGENOM; CLU_168256_0_0_6; -.
DR   Proteomes; UP000002493; Chromosome 1.
DR   GO; GO:0004672; F:protein kinase activity; IEA:UniProt.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.160; HPT domain; 1.
DR   InterPro; IPR036641; HPT_dom_sf.
DR   InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR   NCBIfam; NF041948; Phrelay_LuxU_Vib; 1.
DR   Pfam; PF01627; Hpt; 1.
DR   SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR   PROSITE; PS50894; HPT; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Reference proteome; Two-component regulatory system.
FT   CHAIN           1..112
FT                   /note="Phosphorelay protein LuxU"
FT                   /id="PRO_0000220142"
FT   DOMAIN          17..112
FT                   /note="HPt"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00110"
FT   MOD_RES         56
FT                   /note="Phosphohistidine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00110"
SQ   SEQUENCE   112 AA;  12519 MW;  D841F42526907F9C CRC64;
     MTILNQQKID ELSIEIGSDN VPVLLDIFLG EMDTYIDNLS QLEGSERLMY LKEISHALKS
     SAASFGADSL CELAMSIDKK AKSGELVEQG SEVNTMLDRL NETRDAYRSW TQ
//