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Protein

tRNA pseudouridine synthase C

Gene

truC

Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs.By similarity

Catalytic activityi

tRNA uridine(65) = tRNA pseudouridine(65).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei58 – 581By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciVPAR223926:GHK4-2379-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase C (EC:5.4.99.26)
Alternative name(s):
tRNA pseudouridine(65) synthase
tRNA pseudouridylate synthase C
tRNA-uridine isomerase C
Gene namesi
Name:truC
Ordered Locus Names:VP2322
OrganismiVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Taxonomic identifieri223926 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002493 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 246246tRNA pseudouridine synthase CPRO_0000162721Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi223926.VP2322.

Structurei

3D structure databases

ProteinModelPortaliQ87MD4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase RluA family.Curated

Phylogenomic databases

eggNOGiENOG4105DR9. Bacteria.
COG0564. LUCA.
HOGENOMiHOG000275920.
KOiK06175.
OMAiQHVFPIH.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q87MD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPVELEIVY QDEYFVAVNK PAGMLVHRSW LDKHETQFVM QTLRDQIGQH
60 70 80 90 100
VFPLHRLDRP TSGVLVFALS SEVASQVMPM FAEHKMEKTY HAIVRGWIEE
110 120 130 140 150
EGVLDYALKV ELDKIADKFA SQEKEAQEAV TAYKPLAKVE VPYSTGKFPT
160 170 180 190 200
TRYCLMEMKP KTGRKHQLRR HMAHLRHPIV GDTSHGDGKH NKLFRNEFDS
210 220 230 240
HRLLLHASEL RFVHPFTNEE LVMKASIDDT WQQLFTRFEW DEELVK
Length:246
Mass (Da):28,712
Last modified:June 1, 2003 - v1
Checksum:i89AF262B22FD4E26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA. Translation: BAC60585.1.
RefSeqiNP_798701.1. NC_004603.1.
WP_011106043.1. NC_004603.1.

Genome annotation databases

EnsemblBacteriaiBAC60585; BAC60585; BAC60585.
GeneIDi1189835.
KEGGivpa:VP2322.
PATRICi20142790. VBIVibPar50997_2224.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA. Translation: BAC60585.1.
RefSeqiNP_798701.1. NC_004603.1.
WP_011106043.1. NC_004603.1.

3D structure databases

ProteinModelPortaliQ87MD4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi223926.VP2322.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC60585; BAC60585; BAC60585.
GeneIDi1189835.
KEGGivpa:VP2322.
PATRICi20142790. VBIVibPar50997_2224.

Phylogenomic databases

eggNOGiENOG4105DR9. Bacteria.
COG0564. LUCA.
HOGENOMiHOG000275920.
KOiK06175.
OMAiQHVFPIH.

Enzyme and pathway databases

BioCyciVPAR223926:GHK4-2379-MONOMER.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTRUC_VIBPA
AccessioniPrimary (citable) accession number: Q87MD4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 9, 2003
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.