Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Purine nucleoside phosphorylase DeoD-type 1

Gene

deoD1

Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.UniRule annotation
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei5Purine nucleoside; shared with dimeric partnerBy similarity1
Binding sitei21Phosphate; via amide nitrogenBy similarity1
Binding sitei25PhosphateBy similarity1
Binding sitei44Phosphate; shared with dimeric partnerBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Purine nucleoside phosphorylase DeoD-type 1UniRule annotation (EC:2.4.2.1UniRule annotation)
Short name:
PNP 1UniRule annotation
Gene namesi
Name:deoD1UniRule annotation
Ordered Locus Names:VP2433
OrganismiVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Taxonomic identifieri223926 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002493 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000631741 – 239Purine nucleoside phosphorylase DeoD-type 1Add BLAST239

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Protein-protein interaction databases

STRINGi223926.VP2433.

Structurei

3D structure databases

ProteinModelPortaliQ87M25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni88 – 91Phosphate bindingBy similarity4
Regioni180 – 182Purine nucleoside bindingBy similarity3
Regioni204 – 205Purine nucleoside bindingBy similarity2

Sequence similaritiesi

Belongs to the PNP/UDP phosphorylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D3A. Bacteria.
COG0813. LUCA.
HOGENOMiHOG000274896.
KOiK03784.
OMAiKDHDFSA.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
HAMAPiMF_01627. Pur_nucleosid_phosp. 1 hit.
InterProiIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
PROSITEiPS01232. PNP_UDP_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q87M25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPHINAEM GAFADVVLMP GDPLRAKYIA ETFLEDVVQV CDVRNMFGYT
60 70 80 90 100
GTYKGRKISV MGHGMGIPSC SIYATELIKD FGVKKIIRVG SCGAVNEDIK
110 120 130 140 150
VRDVVIGMGA CTDSKVNRIR FKGHDFAAIA DYKMVRAAED AAKARGIDVK
160 170 180 190 200
VGNLFSAELF YTPDPEMFDV MDKYGIVGVE MEAAGIYGVA AEYGAKALTI
210 220 230
CTVSDHIKTG EQTTSDERQT TFNDMMLIAL DSVLLGDAE
Length:239
Mass (Da):25,895
Last modified:June 1, 2003 - v1
Checksum:i3AE8420A63ECE829
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA. Translation: BAC60696.1.
RefSeqiNP_798812.1. NC_004603.1.
WP_005456104.1. NC_004603.1.

Genome annotation databases

EnsemblBacteriaiBAC60696; BAC60696; BAC60696.
GeneIDi1189946.
KEGGivpa:VP2433.
PATRICi20143010. VBIVibPar50997_2334.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA. Translation: BAC60696.1.
RefSeqiNP_798812.1. NC_004603.1.
WP_005456104.1. NC_004603.1.

3D structure databases

ProteinModelPortaliQ87M25.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi223926.VP2433.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC60696; BAC60696; BAC60696.
GeneIDi1189946.
KEGGivpa:VP2433.
PATRICi20143010. VBIVibPar50997_2334.

Phylogenomic databases

eggNOGiENOG4105D3A. Bacteria.
COG0813. LUCA.
HOGENOMiHOG000274896.
KOiK03784.
OMAiKDHDFSA.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
HAMAPiMF_01627. Pur_nucleosid_phosp. 1 hit.
InterProiIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
PROSITEiPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDEOD1_VIBPA
AccessioniPrimary (citable) accession number: Q87M25
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: June 1, 2003
Last modified: November 2, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.