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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei544 – 5441UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciVPAR223926:GHK4-2855-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:VP2761
OrganismiVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Taxonomic identifieri223926 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000002493 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 877877Phosphoenolpyruvate carboxylasePRO_0000166648Add
BLAST

Proteomic databases

PRIDEiQ87L54.

Interactioni

Protein-protein interaction databases

STRINGi223926.VP2761.

Structurei

3D structure databases

ProteinModelPortaliQ87L54.
SMRiQ87L54. Positions 4-877.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiWGFAVIE.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q87L54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEKYAALKS NVRMLGHLLG NTIRDAHGEE IFEKVETIRK LSKSAQAGNQ
60 70 80 90 100
ADRESLIEEI KHLPDEQLTP VTRAFNQFLN LTNIAEQYHT ISRHCEEHIC
110 120 130 140 150
EPDAINSLFS KLVQNDVSKL DTAQAVRDLN IELVLTAHPT EITRRTMINK
160 170 180 190 200
LVKINECLSK LELSDLSSKE RKKTERRLEQ LIAQSWHSDV IRQQRPTPLD
210 220 230 240 250
EAKWGFAVVE NSLWEAVPDF LREMNDRLKS YLGEGLPIDA RPVHFSSWMG
260 270 280 290 300
GDRDGNPFVT HSVTREVLLL SRWKAADLYL NDINELISEL SMTVSNDQVR
310 320 330 340 350
ELAGEDQHEP YRAILKQLRA LLNETKDILD AKIHGQKLAV KAPLQKVEQL
360 370 380 390 400
WDPLYACYQS LHECGMGVIA DGSLLDTLRR VKAFGVHLVR LDIRQESTRH
410 420 430 440 450
ADVLSELTRY LGIGDYEQWS EQDKIAFLTN ELASKRPLLP RDWEPSEPVK
460 470 480 490 500
EVLDTCKIIA LQPREAFGAY VISMARTASD VLAVHLLLQE AGCPYRMDVC
510 520 530 540 550
PLFETLDDLN NAESVIKQLM SIDLYRGFIQ NHQMVMIGYS DSAKDAGVMS
560 570 580 590 600
AGWAQYHAME SLVKVAEDEG VELTLFHGRG GTVGRGGAPA HAALLSQPPK
610 620 630 640 650
SLKGGLRVTE QGEMIRFKLG LPDVAVNSFN LYASAILEAN LLPPPEPKQE
660 670 680 690 700
WRDLMEVLSE VSCEAYRGVV RGEPDFVPYF RQATPELELG KLPLGSRPAK
710 720 730 740 750
RNPNGGVESL RAIPWIFSWS QNRLVLPAWL GAGEAIQYSV DKGHQALLEE
760 770 780 790 800
MCREWPFFST RLGMLEMVYT KCNMEISRYY DQRLVEPQLQ PLGDRLREQL
810 820 830 840 850
QRDIKSVLNV ENNENLMQSD PWGQESIRLR NIYVEPLNML QAELLYRTRQ
860 870
TEEASANLEE ALMVTIAGIA AGMRNTG
Length:877
Mass (Da):99,273
Last modified:July 25, 2003 - v2
Checksum:i3A61D009D5493105
GO

Sequence cautioni

The sequence BAC61024.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA. Translation: BAC61024.1. Different initiation.
RefSeqiNP_799140.2. NC_004603.1.
WP_005465143.1. NC_004603.1.

Genome annotation databases

EnsemblBacteriaiBAC61024; BAC61024; BAC61024.
GeneIDi1190311.
KEGGivpa:VP2761.
PATRICi20143730. VBIVibPar50997_2657.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000031 Genomic DNA. Translation: BAC61024.1. Different initiation.
RefSeqiNP_799140.2. NC_004603.1.
WP_005465143.1. NC_004603.1.

3D structure databases

ProteinModelPortaliQ87L54.
SMRiQ87L54. Positions 4-877.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi223926.VP2761.

Proteomic databases

PRIDEiQ87L54.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC61024; BAC61024; BAC61024.
GeneIDi1190311.
KEGGivpa:VP2761.
PATRICi20143730. VBIVibPar50997_2657.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiWGFAVIE.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciVPAR223926:GHK4-2855-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae."
    Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K., Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S., Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.
    Lancet 361:743-749(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RIMD 2210633.

Entry informationi

Entry nameiCAPP_VIBPA
AccessioniPrimary (citable) accession number: Q87L54
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: July 25, 2003
Last modified: July 22, 2015
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.