Reviewed, UniProtKB/Swiss-Prot Q87KY6 (SYK3_VIBPA)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Ordered Locus Names:	VP2838

Organism

Vibrio parahaemolyticus [Complete proteome] [HAMAP]

Taxonomic identifier

670 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	323 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 323	323	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_0000152731

Sequences

	Sequence		Length	Mass (Da)
	Q87KY6-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 3EEA38F58FC85B1E	FASTA	323	36,294
	10 20 30 40 50 60 MQTNWQPTAS IEQLRQRATL IAAIRQFFAE RQVMEVDTPA MSHATVTDIH LHTFQTEFVG 70 80 90 100 110 120 PGYADGSKLF FMTSPEFHMK RLLAAGSGCI YQINKAFRNE ENGRYHNPEF TMLEWYRVGF 130 140 150 160 170 180 DHHKLMDEMD DLLQLVLKCG AAQRMTYQQA FIDVLGVCPL EGSMTELKAA ASKLGLSDIA 190 200 210 220 230 240 EPEEDRDTLL QLLFSVGVEN KIGQDVPAFV YDFPASQAAL AKINPQDHRV ADRFEVYFKG 250 260 270 280 290 300 IELANGFHEL DNPKEQLARF EQDNAKRIEM GLKPQPIDYH LISALEAGLP DCAGVALGID 310 320 RLIMLALGCD HIDQVTAFPF PIA

References

[1]

"Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae." Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K., Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S., Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T. Lancet 361:743-749(2003) [PubMed: 12620739] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RIMD 2210633 / Serotype O3:K6.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000031 Genomic DNA. Translation: BAC61101.1.
RefSeq	NP_799217.1.
3D structure databases
HSSP	HSSP built from PDB template 1BBW based on UniProtKB P13030.
ModBase	Search...
Genome annotation databases
GeneID	1190401.
GenomeReviews	Gene locus VP2838 in contig BA000031_GR.
KEGG	vpa:VP2838.
NMPDR	fig|223926.1.peg.2838.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q87KY6.
OMA	VFRNEEA.
Enzyme and pathway databases
BioCyc	VPAR223926:VP2838-MON.
BRENDA	6.1.1.6. 3063.
Family and domain databases
HAMAP	MF_00174. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004525. Lys-tRNA-synth-rel. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR00462. genX. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_VIBPA

Accession

Primary (citable) accession number: Q87KY6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2003
Last sequence update:	June 1, 2003
Last modified:	November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)