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Q87IJ5 (ACKA2_VIBPA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase 2
EC=2.7.2.1
Alternative name(s):
Acetokinase 2
Gene names
Name:ackA2
Ordered Locus Names:VPA0611
OrganismVibrio parahaemolyticus [Complete proteome] [HAMAP]
Taxonomic identifier670 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Acetate kinase 2 HAMAP MF_00020
PRO_0000107640

Sequences

Sequence LengthMass (Da)Tools
Q87IJ5 [UniParc].

Last modified May 23, 2003. Version 1.
Checksum: 6F783ECFF560BE81

FASTA39742,648
        10         20         30         40         50         60 
MSNSFVLVIN SGSSSLKFAV IDSVSGDAVL SGLGECFGLS DARMSWKFNG EKKEISIEGD 

        70         80         90        100        110        120 
DSHHKIAIGK LVGLTEELGL AQDIVAVGHR IVHGGEKFTK TVRITEEVTQ EIEKLADLAP 

       130        140        150        160        170        180 
LHNPAGAIGI RAAVEAFPSL PQFAVFDTAF HQTMPQRAFT GAIAKELYTD FGIRRYGFHG 

       190        200        210        220        230        240 
TSHYFVSREA AKMINKPIEE SSFISVHLGN GASVCAINNG ESVDTSMGFT PLSGLMMGTR 

       250        260        270        280        290        300 
CGDLDPGIIE YLLKKGWSQE KVFNSLNKAS GFLGVSGLTS DARGILEAME EGHEGAALAF 

       310        320        330        340        350        360 
QVFTYRVSKY IASYLAALDS FDGIIFTGGI GENSMPIRRE ILKNLKLLGF VEDVKGNEDA 

       370        380        390 
RFGNAGVIAT SELLGAKALV IPTNEEWVIA QQSVELL

« Hide

References

[1]"Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae."
Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K., Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S., Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.
Lancet 361:743-749(2003) [PubMed: 12620739] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RIMD 2210633 / Serotype O3:K6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000032 Genomic DNA. Translation: BAC61954.1.
RefSeqNP_800121.1. NC_004605.1.

3D structure databases

ProteinModelPortalQ87IJ5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1191300.
GenomeReviewsGene locus VPA0611 in contig BA000032_GR.
KEGGvpa:VPA0611.
NMPDRfig|223926.1.peg.3691.
PATRIC20145635. VBIVibPar50997_3550.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG285863.
OMAAMEEGHE.
ProtClustDBPRK12440.

Enzyme and pathway databases

BioCycVPAR223926:VPA0611-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA2_VIBPA
AccessionPrimary (citable) accession number: Q87IJ5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: May 23, 2003
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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