Reviewed, UniProtKB/Swiss-Prot Q87IJ5 (ACKA2_VIBPA)

Names and origin

Protein names

Recommended name:
    Acetate kinase 2
    EC=2.7.2.1
Alternative name(s):
    Acetokinase 2

Gene names

Name:	ackA2
Ordered Locus Names:	VPA0611

Organism

Vibrio parahaemolyticus [Complete proteome] [HAMAP]

Taxonomic identifier

670 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase 2 HAMAP MF_00020		PRO_0000107640

Sequences

	Sequence		Length	Mass (Da)
	Q87IJ5-1 [UniParc]. Last modified May 23, 2003. Version 1. Checksum: 6F783ECFF560BE81	FASTA	397	42,648
	10 20 30 40 50 60 MSNSFVLVIN SGSSSLKFAV IDSVSGDAVL SGLGECFGLS DARMSWKFNG EKKEISIEGD 70 80 90 100 110 120 DSHHKIAIGK LVGLTEELGL AQDIVAVGHR IVHGGEKFTK TVRITEEVTQ EIEKLADLAP 130 140 150 160 170 180 LHNPAGAIGI RAAVEAFPSL PQFAVFDTAF HQTMPQRAFT GAIAKELYTD FGIRRYGFHG 190 200 210 220 230 240 TSHYFVSREA AKMINKPIEE SSFISVHLGN GASVCAINNG ESVDTSMGFT PLSGLMMGTR 250 260 270 280 290 300 CGDLDPGIIE YLLKKGWSQE KVFNSLNKAS GFLGVSGLTS DARGILEAME EGHEGAALAF 310 320 330 340 350 360 QVFTYRVSKY IASYLAALDS FDGIIFTGGI GENSMPIRRE ILKNLKLLGF VEDVKGNEDA 370 380 390 RFGNAGVIAT SELLGAKALV IPTNEEWVIA QQSVELL

References

[1]

"Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae." Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K., Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S., Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T. Lancet 361:743-749(2003) [PubMed: 12620739] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RIMD 2210633 / Serotype O3:K6.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000032 Genomic DNA. Translation: BAC61954.1.
RefSeq	NP_800121.1.
3D structure databases
HSSP	HSSP built from PDB template 1G99 based on UniProtKB P38502.
ModBase	Search...
Genome annotation databases
GeneID	1191300.
GenomeReviews	Gene locus VPA0611 in contig BA000032_GR.
KEGG	vpa:VPA0611.
NMPDR	fig|223926.1.peg.3691.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q87IJ5.
OMA	HESVLID.
Enzyme and pathway databases
BioCyc	VPAR223926:VPA0611-MON.
BRENDA	2.7.2.1. 3063.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA2_VIBPA

Accession

Primary (citable) accession number: Q87IJ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 23, 2003
Last sequence update:	May 23, 2003
Last modified:	November 3, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)