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Protein

Histidine kinase

Gene

VPA0675

Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotation

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • identical protein binding Source: IntAct
  • phosphorelay sensor kinase activity Source: InterPro

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
Biological processTwo-component regulatory systemSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciVPAR223926:GHK4-3907-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:VPA0675Imported
OrganismiVibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)Imported
Taxonomic identifieri223926 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002493 Componenti: Chromosome 2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 37HelicalSequence analysisAdd BLAST26
Transmembranei334 – 355HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei7624-aspartylphosphatePROSITE-ProRule annotation1
Modified residuei933PhosphohistidinePROSITE-ProRule annotation1

Interactioni

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

DIPiDIP-48299N.
IntActiQ87ID1. 1 interactor.
STRINGi223926.VPA0675.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3I9YX-ray2.16A51-322[»]
3O1HX-ray3.10A51-322[»]
3O1IX-ray2.80A/B51-323[»]
3O1JX-ray2.95A/B51-322[»]
ProteinModelPortaliQ87ID1.
SMRiQ87ID1.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ87ID1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini360 – 412HAMPInterPro annotationAdd BLAST53
Domaini476 – 694Histidine kinaseInterPro annotationAdd BLAST219
Domaini713 – 836Response regulatoryInterPro annotationAdd BLAST124
Domaini894 – 988HPtInterPro annotationAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili140 – 163Sequence analysisAdd BLAST24
Coiled coili413 – 469Sequence analysisAdd BLAST57

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
HOGENOMiHOG000217952.
KOiK07647.
OMAiIAVSAHV.

Family and domain databases

CDDicd06225. HAMP. 1 hit.
cd00075. HATPase_c. 1 hit.
cd00082. HisKA. 1 hit.
cd00088. HPT. 1 hit.
cd00156. REC. 1 hit.
Gene3Di1.20.120.160. 1 hit.
3.30.565.10. 1 hit.
InterProiView protein in InterPro
IPR011006. CheY-like_superfamily.
IPR003660. HAMP_dom.
IPR003594. HATPase_C.
IPR036890. HATPase_C_sf.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR036097. HisK_dim/P_sf.
IPR036641. HPT_dom_sf.
IPR004358. Sig_transdc_His_kin-like_C.
IPR008207. Sig_transdc_His_kin_Hpt_dom.
IPR014302. Sig_transdc_His_kinase_TorS.
IPR001789. Sig_transdc_resp-reg_receiver.
PANTHERiPTHR43719:SF22. PTHR43719:SF22. 1 hit.
PfamiView protein in Pfam
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF01627. Hpt. 1 hit.
PF00072. Response_reg. 1 hit.
PIRSFiPIRSF036437. HK_TorS. 1 hit.
PRINTSiPR00344. BCTRLSENSOR.
SMARTiView protein in SMART
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00448. REC. 1 hit.
SUPFAMiSSF47226. SSF47226. 1 hit.
SSF47384. SSF47384. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR02956. TMAO_torS. 1 hit.
PROSITEiView protein in PROSITE
PS50885. HAMP. 1 hit.
PS50109. HIS_KIN. 1 hit.
PS50894. HPT. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q87ID1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLATASIGR KLLLSFIAMA MLVMLSALIG VSGFSLVAKT ERNVVDAAIP
60 70 80 90 100
AMIEARQVSE LSTRIISSVQ MLSNAQNEQE RKEAGRVLFE QLESLLTHIK
110 120 130 140 150
ELGGESFDSK LLDALESNVQ NVINNLAELG VTVERKLWLA KEIDTRVEEM
160 170 180 190 200
RLLSEELEQL TRTQVQNTST IAVANVTHIY DLLEANKKDQ VYQALDALVE
210 220 230 240 250
VDLDLTERLH ELHLLAFKML NQIEEARTLT NVDRIQQIQT AFENNLKIMK
260 270 280 290 300
RRVLAVEDPT RSKQMSQLLT ELGKRQVVFT ILLQQYENNE QSQQLMQKTL
310 320 330 340 350
ELFSELNSTV NKLVDDSNKT TTFAVDQLTN TLKFAQWSLT VISIVGLIVV
360 370 380 390 400
VLILWRVVYV SVVKRLAEYS AALLSVAQGN LAVELEVKGK DELAHMGQAI
410 420 430 440 450
ITARNTAQAL KVVAEGEAKA KRELEEHKEH LEELIEQRTS QLRQANLRLN
460 470 480 490 500
EEVVNHAQAR NEAEQASRAK SAFLATMSHE IRTPMNGVLG TARLLMDSGL
510 520 530 540 550
NPIQKRYAEI INRSGKTLLA ILNDVLDYSK IEAGHLEIRR LGFDLHQMVE
560 570 580 590 600
DTFQLMNSRA QEKQLLFSYH IESDVSRYWK GDVTRISQVL NNLVGNAIKF
610 620 630 640 650
TEDGEIDIYV SLNPEDESQV LFEVSDTGIG ISKKDQKTLF DAFTQAEGGL
660 670 680 690 700
NQIGGTGLGL AISKRIVEAM GGVLEVDSEE GEGSRFWFSI PLEESEPVEI
710 720 730 740 750
GVVASARCKV KAKVLLVEDN EVNRVVAEGF LQSMGHQVVM AEDGLQAERI
760 770 780 790 800
IDKQDFDIAL VDINLPDCDG TDLIQRLKRI ERNKPGDKAL SPTPMIAVSA
810 820 830 840 850
HVFAEEVERY LAAGFDGYLP KPVEKEALAT LIQDVLDGKQ LLLPQSGECL
860 870 880 890 900
PLSETSDTNL TIENQVEQDH QQREEPEMVI INPSVIQSDM KILGREKMLH
910 920 930 940 950
IIDLFRNTSA DVLGQLVESA EKNDSLAVKN LAHKLKGSAG SLGLTALMNT
960 970 980
CQSIEIAAEP LDTYNAQQGL LDEQVATSVN ALDELMAE
Length:988
Mass (Da):109,883
Last modified:June 1, 2003 - v1
Checksum:i962F67DF6A44BC72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000032 Genomic DNA. Translation: BAC62018.1.
RefSeqiNP_800185.1. NC_004605.1.
WP_005477577.1. NC_004605.1.

Genome annotation databases

EnsemblBacteriaiBAC62018; BAC62018; BAC62018.
GeneIDi1191364.
KEGGivpa:VPA0675.
PATRICifig|223926.6.peg.3611.

Similar proteinsi

Entry informationi

Entry nameiQ87ID1_VIBPA
AccessioniPrimary (citable) accession number: Q87ID1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 22, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported