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Q87CN8 (UPPP_XYLFT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:PD_1027
OrganismXylella fastidiosa (strain Temecula1 / ATCC 700964) [Complete proteome] [HAMAP]
Taxonomic identifier183190 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella

Protein attributes

Sequence length261 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 261261Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151245

Regions

Transmembrane38 – 5821Helical; Potential
Transmembrane75 – 9521Helical; Potential
Transmembrane106 – 12621Helical; Potential
Transmembrane136 – 15621Helical; Potential
Transmembrane181 – 20121Helical; Potential
Transmembrane217 – 23721Helical; Potential
Transmembrane241 – 26121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q87CN8 [UniParc].

Last modified June 16, 2003. Version 1.
Checksum: 07BC374F7B31375A

FASTA26128,695
        10         20         30         40         50         60 
MFELFTALML GILEGITEFL PVSSTGHLLI AEHWLGSRSD FFNIVIQAGA ILAITFVFRK 

        70         80         90        100        110        120 
KVWSLATGLD KYSNRDYVMK LATAFLITAV VGLAVRKANW QLPETIQPIA WALIIGGIWI 

       130        140        150        160        170        180 
LIAESVAKHL PERENVTWSV AIAVGLAQVV AGVFPGTSRS ASTIFLAMLL GLSKRSAAAE 

       190        200        210        220        230        240 
FSFLVGIPTM FSASSYACFE LFKRGELLHE NWLEVSVAFV AAMLTGFAVV KWLLGYIKNH 

       250        260 
SFAPFAYYRI ALGLVLLTWL T 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE009442 Genomic DNA. Translation: AAO28887.1.
RefSeqNP_779238.1. NC_004556.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING183190.PD1027.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO28887; AAO28887; PD_1027.
GeneID1143749.
KEGGxft:PD1027.
PATRIC24150022. VBIXylFas71109_1323.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
KOK06153.
OMAFNDAHAK.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycXFAS183190:GIX4-1027-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_XYLFT
AccessionPrimary (citable) accession number: Q87CN8
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: June 16, 2003
Last modified: May 14, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families