Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tryptophan--tRNA ligase

Gene

trpS

Organism
Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the attachment of tryptophan to tRNA(Trp).UniRule annotation

Catalytic activityi

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei143L-tryptophanUniRule annotation1
Binding sitei195ATP; via amide nitrogen and carbonyl oxygenUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 12ATPUniRule annotation3
Nucleotide bindingi18 – 19ATPUniRule annotation2
Nucleotide bindingi155 – 157ATPUniRule annotation3
Nucleotide bindingi202 – 206ATPUniRule annotation5

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tryptophan--tRNA ligaseUniRule annotation (EC:6.1.1.2UniRule annotation)
Alternative name(s):
Tryptophanyl-tRNA synthetaseUniRule annotation
Short name:
TrpRSUniRule annotation
Gene namesi
Name:trpSUniRule annotation
Ordered Locus Names:PD_1650
OrganismiXylella fastidiosa (strain Temecula1 / ATCC 700964)
Taxonomic identifieri183190 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
Proteomesi
  • UP000002516 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001367151 – 435Tryptophan--tRNA ligaseAdd BLAST435

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ87B10
SMRiQ87B10
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi11 – 19"HIGH" regionUniRule annotation9
Motifi202 – 206"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

KOiK01867
OMAiQRMTQFK

Family and domain databases

CDDicd00806 TrpRS_core, 1 hit
Gene3Di3.40.50.620, 2 hits
HAMAPiMF_00140_B Trp_tRNA_synth_B, 1 hit
InterProiView protein in InterPro
IPR002305 aa-tRNA-synth_Ic
IPR014729 Rossmann-like_a/b/a_fold
IPR002306 Trp-tRNA-ligase
IPR024109 Trp-tRNA-ligase_bac-type
IPR036913 YegP-like_sf
PfamiView protein in Pfam
PF00579 tRNA-synt_1b, 1 hit
PRINTSiPR01039 TRNASYNTHTRP
SUPFAMiSSF160113 SSF160113, 1 hit
TIGRFAMsiTIGR00233 trpS, 1 hit

Sequencei

Sequence statusi: Complete.

Q87B10-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIRVLTGIT TSGTPHLGNY VGAIRPAIRA AGAPGTESFY FLADLHSLIK
60 70 80 90 100
VQDPERTQRS TLEIAATWLA CGLDPEKVWL YRQSDVPEIT ELMWLLTCVA
110 120 130 140 150
GKGILNRAHA YKAVVDKNRS HGDDDDAGIT AGLFMYPVLM AADILLFNAH
160 170 180 190 200
QVPVGRDQIQ HIEMARDFAQ RFNHIYGGEY LVLPEAAIDE QVATLPGLDG
210 220 230 240 250
RKMSKSYGNT MPLFCTREEL KKYVFSIVTD SRAPGEPKEA VGSAVFQLYQ
260 270 280 290 300
AFAGVEECSM FAQALVEGLG WGEAKVRLFE RIDAEVAPLR ERYEDFMRRP
310 320 330 340 350
ADIEAMLRDS AGRLRERDAI PLLARLREAV GLRSLSLCMV SAVPVPQEKV
360 370 380 390 400
ALPVLKQYRE QDGRFYFKLI DGQGAVLVQS RGFASPRDAG QWIALFKQVV
410 420 430
SAEALVSPML EPVADPVVVL AALRRLREAG LDLYT
Length:435
Mass (Da):48,154
Last modified:June 16, 2003 - v1
Checksum:i09DA1282A16206EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009442 Genomic DNA Translation: AAO29490.1
RefSeqiWP_004089825.1, NC_004556.1

Genome annotation databases

EnsemblBacteriaiAAO29490; AAO29490; PD_1650
KEGGixft:PD_1650

Similar proteinsi

Entry informationi

Entry nameiSYW_XYLFT
AccessioniPrimary (citable) accession number: Q87B10
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: June 16, 2003
Last modified: March 28, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health