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Q87B10 (SYW_XYLFT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tryptophan--tRNA ligase

EC=6.1.1.2
Alternative name(s):
Tryptophanyl-tRNA synthetase
Short name=TrpRS
Gene names
Name:trpS
Ordered Locus Names:PD_1650
OrganismXylella fastidiosa (strain Temecula1 / ATCC 700964) [Complete proteome] [HAMAP]
Taxonomic identifier183190 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella

Protein attributes

Sequence length435 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp). HAMAP-Rule MF_00140

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00140

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00140.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtryptophanyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tryptophan-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 435435Tryptophan--tRNA ligase HAMAP-Rule MF_00140
PRO_0000136715

Regions

Motif11 – 199"HIGH" region HAMAP-Rule MF_00140
Motif202 – 2065"KMSKS" region HAMAP-Rule MF_00140

Sites

Binding site2051ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q87B10 [UniParc].

Last modified June 16, 2003. Version 1.
Checksum: 09DA1282A16206EC

FASTA43548,154
        10         20         30         40         50         60 
MSIRVLTGIT TSGTPHLGNY VGAIRPAIRA AGAPGTESFY FLADLHSLIK VQDPERTQRS 

        70         80         90        100        110        120 
TLEIAATWLA CGLDPEKVWL YRQSDVPEIT ELMWLLTCVA GKGILNRAHA YKAVVDKNRS 

       130        140        150        160        170        180 
HGDDDDAGIT AGLFMYPVLM AADILLFNAH QVPVGRDQIQ HIEMARDFAQ RFNHIYGGEY 

       190        200        210        220        230        240 
LVLPEAAIDE QVATLPGLDG RKMSKSYGNT MPLFCTREEL KKYVFSIVTD SRAPGEPKEA 

       250        260        270        280        290        300 
VGSAVFQLYQ AFAGVEECSM FAQALVEGLG WGEAKVRLFE RIDAEVAPLR ERYEDFMRRP 

       310        320        330        340        350        360 
ADIEAMLRDS AGRLRERDAI PLLARLREAV GLRSLSLCMV SAVPVPQEKV ALPVLKQYRE 

       370        380        390        400        410        420 
QDGRFYFKLI DGQGAVLVQS RGFASPRDAG QWIALFKQVV SAEALVSPML EPVADPVVVL 

       430 
AALRRLREAG LDLYT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE009442 Genomic DNA. Translation: AAO29490.1.
RefSeqNP_779841.1. NC_004556.1.

3D structure databases

ProteinModelPortalQ87B10.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING183190.PD1650.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO29490; AAO29490; PD_1650.
GeneID1142992.
KEGGxft:PD1650.
PATRIC24151640. VBIXylFas71109_2123.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0180.
KOK01867.
OMAWEMLIDW.
OrthoDBEOG686NJQ.

Enzyme and pathway databases

BioCycXFAS183190:GIX4-1650-MONOMER.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_00140_B. Trp_tRNA_synth_B.
InterProIPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view]
PANTHERPTHR10055. PTHR10055. 1 hit.
PfamPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSPR01039. TRNASYNTHTRP.
TIGRFAMsTIGR00233. trpS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYW_XYLFT
AccessionPrimary (citable) accession number: Q87B10
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: June 16, 2003
Last modified: May 14, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries