Q87AK0 (DADA_XYLFT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-amino acid dehydrogenase small subunit
EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	PD_1824

Organism

Xylella fastidiosa (strain Temecula1 / ATCC 700964) [Complete proteome] [HAMAP]

Taxonomic identifier

183190 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xylella

Protein attributes

Sequence length	435 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202
Cofactor	FAD By similarity. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 435	435	D-amino acid dehydrogenase small subunit HAMAP MF_01202		PRO_0000166158
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	Q87AK0 [UniParc]. Last modified June 16, 2003. Version 1. Checksum: F30FC0AD17106A5E	FASTA	435	47,540
	10 20 30 40 50 60 MRVLILGSGV IGTTSAWYLS KAGCEVVVVD RQSGAGLETS YANGGQLSFG YTSPWAAPGV 70 80 90 100 110 120 PLKAVRWLFE RHAPLSIRPT TDWNQYVWLA RMLRHCSAER YAVNKSRMLR LSEYSREALE 130 140 150 160 170 180 ALSAETGITF EGRRLGTIQL FRTQQQLDGA VRDIELLTQY GIPYEVLSPH QLAKFEPGLA 190 200 210 220 230 240 DGSVRFVGAL RLPHDQTGDC CLFTQRLAAL AAKRGVEFRY GCTVQRLEVD GPRVTGAWIN 250 260 270 280 290 300 GALERADCCV VALGSYSPLL LAPLGLRLPV YPLKGFSLTL PMIDASRAPV STVLDESYKV 310 320 330 340 350 360 AVTRFDERIR VAGMAEVSGY DVSLNPRRRS TLEMVVQDVY PGCGDLGRGE FWTGLRPATP 370 380 390 400 410 420 DGTPVIGATP YQGLFLNTGH GTLGWTMSSG SGRYLADLIC CRPCEISSEG LDMFRYLVST 430 IPCPQECAPC VPPTP

References

[1]

"Comparative analyses of the complete genome sequences of Pierce's disease and citrus variegated chlorosis strains of Xylella fastidiosa." Van Sluys M.A., de Oliveira M.C., Monteiro-Vitorello C.B., Miyaki C.Y., Furlan L.R., Camargo L.E.A., da Silva A.C.R., Moon D.H., Takita M.A., Lemos E.G.M., Machado M.A., Ferro M.I.T., da Silva F.R., Goldman M.H.S., Goldman G.H., Lemos M.V.F., El-Dorry H., Tsai S.M. , Carrer H., Carraro D.M., de Oliveira R.C., Nunes L.R., Siqueira W.J., Coutinho L.L., Kimura E.T., Ferro E.S., Harakava R., Kuramae E.E., Marino C.L., Giglioti E., Abreu I.L., Alves L.M.C., do Amaral A.M., Baia G.S., Blanco S.R., Brito M.S., Cannavan F.S., Celestino A.V., da Cunha A.F., Fenille R.C., Ferro J.A., Formighieri E.F., Kishi L.T., Leoni S.G., Oliveira A.R., Rosa V.E. Jr., Sassaki F.T., Sena J.A.D., de Souza A.A., Truffi D., Tsukumo F., Yanai G.M., Zaros L.G., Civerolo E.L., Simpson A.J.G., Almeida N.F. Jr., Setubal J.C., Kitajima J.P. J. Bacteriol. 185:1018-1026(2003) [PubMed: 12533478] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Temecula1 / ATCC 700964.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009442 Genomic DNA. Translation: AAO29657.1.
RefSeq	NP_780008.1. NC_004556.1.
3D structure databases
ProteinModelPortal	Q87AK0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q87AK0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1143166.
GenomeReviews	Gene locus PD_1824 in contig AE009442_GR.
KEGG	xft:PD1824.
PATRIC	24152120. VBIXylFas71109_2358.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0665.
HOGENOM	HBG729204.
OMA	LEHAGGQ.
ProtClustDB	PRK00711.
Enzyme and pathway databases
BioCyc	XFAS183190:PD_1824-MONOMER.
Family and domain databases
HAMAP	MF_01202. DadA. [Tree]
InterPro	IPR023080. D-aa_DH_ssu_DadA. IPR006076. FAD-dep_OxRdtase. [Graphical view]
KO	K00285.
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DADA_XYLFT

Accession

Primary (citable) accession number: Q87AK0

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2003
Last sequence update:	June 16, 2003
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program