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Q874T6 (GLNA_KLULA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine synthetase

Short name=GS
EC=6.3.1.2
Alternative name(s):
Glutamate--ammonia ligase
Gene names
Name:GLN1
Ordered Locus Names:KLLA0E06259g
OrganismKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) [Complete proteome]
Taxonomic identifier284590 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces

Protein attributes

Sequence length372 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Subunit structure

Homooctamer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the glutamine synthetase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 372372Glutamine synthetase
PRO_0000153160

Sequences

Sequence LengthMass (Da)Tools
Q874T6 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 70023A50041D1E65

FASTA37241,677
        10         20         30         40         50         60 
MAATSDIVEK THILQKYLEL DQRGAIIAEY VWIDSEGGLR SKGRTLNKKV TSVDSLPEWN 

        70         80         90        100        110        120 
FDGSSTGQAP GHDSDIYLKP VAFYPDPFRR GDNIVVLAEC WNNDGTPNKF NHRHEAAKLF 

       130        140        150        160        170        180 
EAHKDAEMWF GLEQEYTLFD QYDQVYGWPK GGFPAPQGPY YCGVGAGKVF ARDVIEAHYR 

       190        200        210        220        230        240 
ACLYAGVNIS GINAEVMPSQ WEFQVGPCEG IAMADQLWIA RYFLHRVAEE FGVKVSLHPK 

       250        260        270        280        290        300 
PLKGDWNGAG CHTNVSTKLM RAPGGMKYIE DAIEKLSKRH NEHIKLYGAD NEQRLTGRHE 

       310        320        330        340        350        360 
TASMSTFSSG VANRGASIRI PRSVNKEGYG YFEDRRPASN IDPYLVTGIM CETVCGAIEN 

       370 
ANMTKEYERE SL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ547613 Genomic DNA. Translation: CAD67983.1.
CR382125 Genomic DNA. Translation: CAG99318.1.
RefSeqXP_454231.1. XM_454231.1.

3D structure databases

ProteinModelPortalQ874T6.
SMRQ874T6. Positions 21-355.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING28985.Q874T6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2894685.
KEGGkla:KLLA0E06293g.

Phylogenomic databases

eggNOGCOG0174.
HOGENOMHOG000061500.
KOK01915.
OMAGTPYGWP.
OrthoDBEOG7GTTD8.

Family and domain databases

Gene3D3.30.590.10. 1 hit.
InterProIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMSSF54368. SSF54368. 1 hit.
PROSITEPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLNA_KLULA
AccessionPrimary (citable) accession number: Q874T6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: June 1, 2003
Last modified: November 13, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families