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Protein

Endo-1,4-beta-xylanase

Gene

B8G12.010

Organism
Neurospora crassa
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.UniRule annotation

Pathwayi: xylan degradation

This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei120NucleophilePROSITE-ProRule annotation1
Active sitei211Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidasePROSITE-ProRule annotation, Hydrolase
Biological processCarbohydrate metabolism, Polysaccharide degradation, Xylan degradationPROSITE-ProRule annotationImported

Enzyme and pathway databases

UniPathwayiUPA00114.

Protein family/group databases

CAZyiCBM1. Carbohydrate-Binding Module Family 1.
GH11. Glycoside Hydrolase Family 11.

Names & Taxonomyi

Protein namesi
Recommended name:
Endo-1,4-beta-xylanasePROSITE-ProRule annotation (EC:3.2.1.8PROSITE-ProRule annotation)
Gene namesi
Name:B8G12.010Imported
ORF Names:GE21DRAFT_8457Imported
OrganismiNeurospora crassaImported
Taxonomic identifieri5141 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
Proteomesi
  • UP000053122 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500771273721 – 293Endo-1,4-beta-xylanaseSequence analysisAdd BLAST273

Interactioni

Protein-protein interaction databases

STRINGi5141.EFNCRP00000007212.

Structurei

3D structure databases

ProteinModelPortaliQ871E8.
SMRiQ871E8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 224GH11 (glycosyl hydrolase family 11)InterPro annotationAdd BLAST189
Domaini257 – 293CBM1 (fungal-type carbohydrate-binding)InterPro annotationAdd BLAST37

Sequence similaritiesi

Belongs to the glycosyl hydrolase 11 (cellulase G) family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IGA5. Eukaryota.
ENOG410YH6C. LUCA.

Family and domain databases

Gene3Di2.60.120.180. 1 hit.
InterProiView protein in InterPro
IPR000254. Cellulose-bd_dom_fun.
IPR013320. ConA-like_dom.
IPR013319. GH11/12.
IPR018208. GH11_AS_1.
IPR033119. GH11_AS_2.
IPR033123. GH11_dom.
IPR001137. Glyco_hydro_11.
PfamiView protein in Pfam
PF00734. CBM_1. 1 hit.
PF00457. Glyco_hydro_11. 1 hit.
PRINTSiPR00911. GLHYDRLASE11.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001821. CBD_fun. 1 hit.
SMARTiView protein in SMART
SM00236. fCBD. 1 hit.
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF57180. SSF57180. 1 hit.
PROSITEiView protein in PROSITE
PS00562. CBM1_1. 1 hit.
PS51164. CBM1_2. 1 hit.
PS00776. GH11_1. 1 hit.
PS00777. GH11_2. 1 hit.
PS51761. GH11_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q871E8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAFSSILLA ASTAISGVFA LPGELPGQGS LFKRQTYTSS ATGTHNGYYF
60 70 80 90 100
SFWTDGQGSV RYTNEAGGQY TATWSGNGNW VGGKGWMPGT DRTINYTGTY
110 120 130 140 150
SPNGNSYLAV YGWTRNPLIE YYVVENFGTY NPSTGATRLG SVTSDGGVYD
160 170 180 190 200
IYRTQRVNQP SIDGTATFYQ YWSVRQQKRT GGSVNMKNHF DAWTRSGLTL
210 220 230 240 250
GTHNYQIVAT EGYFSSGSST INVGASGGSG GGGGGTTPEN PGTTTTPTNP
260 270 280 290
GNGGGGSCAA KWGQCGGQGW SGATCCQSGS TCQAANQWYS QCV
Length:293
Mass (Da):30,776
Last modified:June 1, 2003 - v1
Checksum:iD67A81CE65930F26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX294027 Genomic DNA. Translation: CAD71059.1.
KN389658 Genomic DNA. Translation: KHE85744.1.

Genome annotation databases

EnsemblFungiiKHE85744; KHE85744; GE21DRAFT_8457.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ871E8_NEUCS
AccessioniPrimary (citable) accession number: Q871E8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 5, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported