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Protein

Gag polyprotein

Gene
N/A
Organism
Simian immunodeficiency virus - agm.sab-1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Host-virus interaction, Viral budding, Viral budding via the host ESCRT complexesSAAS annotation, Virus exit from host cell

Keywords - Ligandi

Metal-binding, RNA-bindingUniRule annotationSAAS annotation, Viral nucleoproteinUniRule annotation, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Gag polyproteinUniRule annotationSAAS annotation
OrganismiSimian immunodeficiency virus - agm.sab-1Imported
Taxonomic identifieri349974 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group

Subcellular locationi

  • Host cytoplasm SAAS annotation
  • Host nucleus SAAS annotation
  • Virion UniRule annotation
  • Host nucleus UniRule annotation
  • Host cytoplasm UniRule annotation
  • Virion UniRule annotation
  • Host cytoplasm UniRule annotation
  • Host nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid proteinUniRule annotationSAAS annotation, Host cytoplasmUniRule annotationSAAS annotation, Host nucleusUniRule annotationSAAS annotation, Virion

PTM / Processingi

Post-translational modificationi

Gag-Pol polyprotein: Specific enzymatic cleavages by the viral protease yield mature proteins.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ87107.
SMRiQ87107. Positions 6-117, 156-365, 415-457.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini417 – 43216CCHC-typeInterPro annotationAdd
BLAST
Domaini439 – 45416CCHC-typeInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the primate lentivirus group gag polyprotein family.SAAS annotation
Contains CCHC-type zinc fingers.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerUniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.1200.30. 1 hit.
1.10.150.90. 1 hit.
1.10.375.10. 1 hit.
4.10.60.10. 1 hit.
InterProiIPR000721. Gag_p24.
IPR000071. Lentvrl_matrix_N.
IPR012344. Matrix_HIV/RSV.
IPR008916. Retrov_capsid_C.
IPR008919. Retrov_capsid_N.
IPR010999. Retrovr_matrix.
IPR001878. Znf_CCHC.
[Graphical view]
PfamiPF00540. Gag_p17. 1 hit.
PF00607. Gag_p24. 1 hit.
PF00098. zf-CCHC. 2 hits.
[Graphical view]
PRINTSiPR00234. HIV1MATRIX.
SMARTiSM00343. ZnF_C2HC. 2 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
SSF47836. SSF47836. 1 hit.
SSF47943. SSF47943. 1 hit.
SSF57756. SSF57756. 1 hit.
PROSITEiPS50158. ZF_CCHC. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q87107-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGASNSVLSG RKLDAFESVR LRPNGKKKYK LRHLVWASKE LDRFSLSANL
60 70 80 90 100
LETKEGVVKI LSVLLPLVPT GSENLIALFN LCCVLACIHA EIKVKDTEEA
110 120 130 140 150
KAKVKEEVPA EMTESATATS SGQTKELQAK KKNEPTVTPS GGSRNYPIVS
160 170 180 190 200
VNNQWVHQPL SPRTLNAWVK VIEEKKFSAE VVPMFSALAE GAIPYDINQM
210 220 230 240 250
LNAVGEHQGA LQIVKDVINE EAADWDLRHP PPQQPPAQGV LRDPQGSDIA
260 270 280 290 300
GTTSTIQEQI EWTTRAQNAV NVGNIYKGWI ILGLQKCVKM YNPVNILDIK
310 320 330 340 350
QGPKEPFKDY VDRFYKALRA EQTDPAVKNW MTQSLLIQNA NPDCKTVLKG
360 370 380 390 400
LGMNPTLEEM LTACQGIGGA QHKARLMAEA MTAAFQQQTV GNIFVQQGAR
410 420 430 440 450
PRGPLGGRGR PLNPNIKCYN CGKPGHLARF CKAPRRQGCW KCGSPDHQMK
460 470 480 490 500
DCQKQVNFLG FGPWGRGKPR NFPLTSIRPT APPMERDYSR PEENWYADRP
510 520 530 540 550
PTRGPGPDDP ATALLKQYAV QGKRQKQQWQ NHSPQQSPYE EAYSSLRSLF

GEDQ
Length:554
Mass (Da):61,535
Last modified:November 1, 1996 - v1
Checksum:i7258653BA58C1D36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U04005 Genomic DNA. Translation: AAA21504.1.

Keywords - Coding sequence diversityi

Ribosomal frameshiftingSAAS annotation

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U04005 Genomic DNA. Translation: AAA21504.1.

3D structure databases

ProteinModelPortaliQ87107.
SMRiQ87107. Positions 6-117, 156-365, 415-457.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.1200.30. 1 hit.
1.10.150.90. 1 hit.
1.10.375.10. 1 hit.
4.10.60.10. 1 hit.
InterProiIPR000721. Gag_p24.
IPR000071. Lentvrl_matrix_N.
IPR012344. Matrix_HIV/RSV.
IPR008916. Retrov_capsid_C.
IPR008919. Retrov_capsid_N.
IPR010999. Retrovr_matrix.
IPR001878. Znf_CCHC.
[Graphical view]
PfamiPF00540. Gag_p17. 1 hit.
PF00607. Gag_p24. 1 hit.
PF00098. zf-CCHC. 2 hits.
[Graphical view]
PRINTSiPR00234. HIV1MATRIX.
SMARTiSM00343. ZnF_C2HC. 2 hits.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
SSF47836. SSF47836. 1 hit.
SSF47943. SSF47943. 1 hit.
SSF57756. SSF57756. 1 hit.
PROSITEiPS50158. ZF_CCHC. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ87107_SIVSA
AccessioniPrimary (citable) accession number: Q87107
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.